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State · North America

Pennsylvania

State · United States · Pop. 13.1M · #23 region by EV

A public taster of the full Pennsylvania ecosystem on Dealroom — request a demo for live deal flow, founder pedigrees, AI-talent maps, and the full cap table for every company below.

$263B+37%
Combined startup EV
$2.9B
VC invested (last 12mo)
2,518
Tracked startups
#26/ 69
Unicorns per 1M people · regions rank
🦄 Unicorns
32
32 live · +3 new in 2025 (incl. 1 new decacorns)
💎 Decacorns
4
$10B+ tier
🐎 Thoroughbreds
27
Top 1% growth · $500M+

Enterprise value · 2015–2025

Pennsylvania grew 7.0× since 2015

Combined enterprise value of every tracked startup headquartered in Pennsylvania that's still operating today — public and private companies combined, totalled by founding-year cohort.

0 $75B $150B $225B $300B Pennsylvania · $271B 2015 2018 2021 2024 2025

Adjacent regions by EV

Startup funnel

Pennsylvania's power-law funnel

From the first cheque written to a $10B+ outcome. Each arrow shows what fraction of companies at one stage graduate to the next, tracked by founding cohort.

Pre-Seed
574
Seed
432
Series A
358
Series B
186
Series C
140
Unicorn
27
Decacorn
5

* C→Unicorn and Unicorn→Decacorn rates are derived from current counts (no founding-cohort data); the four mid-funnel rates use Dealroom's cohort tracking.

Notable companies

Top private companies in Pennsylvania

Up to 20 names per tier from Dealroom's tracked dataset. Decacorns are valued $10B+, unicorns $1B+, thoroughbreds have crossed $100M in revenue.

Decacorns $10B+ valuation 5
GopuffAuroraSkildGlobus MedicalMadrigal Pharmaceuticals
Unicorns $1B+ valuation 27
3m M*ModalGreenphireAmicus TherapeuticsHyliionPalvella TherapeuticsProvention BioPhenom PeopleAbridgedbt LabsDuolingoBioTelemetryIkariaEnvestnetStack AVQlikSignant HealthShift4 | Lighthouse NetworkAgility RoboticsSpark TherapeuticsEPAM Systems+7 more
Thoroughbreds+ $100M+ revenue 25
EPAM SystemsShift4 | Lighthouse NetworkAdaptHealthGlobus MedicalEnvestnetDuolingoHarmony BiosciencesAmicus TherapeuticsAtriCureKrystal BiotechMadrigal PharmaceuticalsGoviniAbridgeBeyondTabula Rasa Healthcare (formerly CareKinesis)AccoladeSimpleTire.comGecko RoboticsDuckDuckGodbt Labs

Academia

Pennsylvania's academic flywheel

Companies founded by university alumni or spun out of research, plus the institutions producing the most founders tied to Pennsylvania.

University-linked startup formation
290
University spinouts
6,335
Total alumni-founded companies
3,560
Of which startups (<$15M raised)
1,936
Breakouts ($15M-100M)
839
Scaleups ($100M+)
Top universities producing founders tied to Pennsylvania
  • 🇺🇸 University of Pennsylvania Philadelphia, PA · 165 alumni unicorns
    Notable alumni-founded: Warby ParkerCompassBetterCloudOutschool
  • 🇺🇸 Carnegie Mellon University Pittsburgh, PA · 88 alumni unicorns
    Notable alumni-founded: DuolingoAuroraArgo AIASAPP

Vs. similarly-sized ecosystems

How Pennsylvania stacks up

Peers chosen from the same country (United States), sized closest to Pennsylvania by combined EV. The scatter plots growth × current size — outliers in the upper-right are ecosystems compounding fastest.

Combined enterprise value
$729B
$264B
Pennsylvania
$263B
$215B
$188B
$170B
EV growth (5-yr ×) vs current EV
peer median 4.4× 1.6× 16.1× 30.6× $5.2B $337B $21.7T EV growth (5yr ×) Combined enterprise value (log) California Western United States (Pacific, excl. Bay Area) Northeastern United States Washington (State) Texas New York State Southeastern United States Massachusetts Florida Midwestern United States Western United States (Mountain) Illinois New Jersey Colorado Pennsylvania

Top overview

United States — top regions

Top regions in United States ranked by combined EV. Pennsylvania's row is highlighted.

# Ecosystem Combined EV 5-yr EV growth Unicorns VC invested Tracked startups
1 California $21.7T 7.7× 976 $180B 36.4K
2 Western United States (Pacific, excl. Bay Area) $4.8T 8.1× 279 $29.9B 16.3K
3 Northeastern United States $3.5T 4.9× 571 $52.8B 30.2K
4 Washington (State) $3.1T 10.6× 72 $7.3B 3,203
5 Texas $2.3T 10.0× 107 $11.2B 6,215
6 New York State $1.5T 5.4× 270 $29.9B 15.3K
7 Southeastern United States $1.3T 5.3× 145 $11.4B 13.6K
8 Massachusetts $1.2T 4.5× 184 $13.5B 5,968
9 Florida $729B 9.7× 49 $3.9B 4,511
10 Midwestern United States $654B 3.6× 104 $9.2B 10.8K
11 Western United States (Mountain) $346B 4.0× 86 $9.1B 5,151
13 Pennsylvania $263B 4.8× 32 $2.9B 2,518

Premium analytics

What we don't show on this page (yet)

Sector breakdowns, founder origins, AI-talent leaderboards and live deal flow are gated to logged-in Dealroom users. Book a demo to access the full Pennsylvania dataset — or see a sample on the Dealroom app.

Sector breakdown
Where Pennsylvania's unicorns concentrate
Fintech
AI / Enterprise SW
Health Tech
Biotech
Cybersecurity
Consumer
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Capital autonomy
Pennsylvania's domestic vs foreign capital mix
% domestic VC by stage
Cross-border lead investors
Sovereign-fund participation
Foreign-LP exposure
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Recent momentum
Pennsylvania's VC investment trajectory by stage
2024 vs 2025 by stage
Round-size trends
Stage-conversion deltas
Quarterly velocity
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Founder origins
Where Pennsylvania's startup founders come from
By country of origin
Per capita
Top universities
Top alumni-factory companies
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AI talent
Top employers of AI talent in Pennsylvania
Core AI roles
Frontier AI roles
YoY hiring growth
Senior + lead engineers
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Deal flow
Live deal flow & funding rounds in Pennsylvania
New rounds last 30 days
Stage breakdown
Active investors
Round-size trends
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