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St. Louis

Metro area · United States · Pop. 2.8M

A public taster of the full St. Louis ecosystem on Dealroom — request a demo for live deal flow, founder pedigrees, AI-talent maps, and the full cap table for every company below.

386 Pool of Funded Startups
88 Annual Startups FoundedAll new ventures
33 Annual Startups FundedReceived investment
get funded 37%
129 Pre-Seed Startups$100K–1M
92 Seed Startups$1–4M
80 Series A Startups$4–15M
Seed to Series A 28%
50 Series B Breakouts$15–40M
A to Series B 41%
19 Series C Breakouts$40–100M
11 Mega Scaleups$100–250M
reach Mega 2.8%
5 Mega+ Scaleups$250M+
reach Mega+ 1.3%
4 Unicorns($1–10B valuation)
reach Unicorn 1.0%
Pre-Seed
129
Seed
92
Series A
80
Series B
50
Series C
19
Unicorn
4

* C→Unicorn and Unicorn→Decacorn rates are derived from current counts (no founding-cohort data); the four mid-funnel rates use Dealroom's cohort tracking.

Quarterly report

St. Louis's latest quarter in venture capital

VC raised by St. Louis-headquartered companies in the quarter shown, against the quarter before and the same quarter a year earlier.

Latest complete quarter

 

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Largest rounds

Largest funding rounds in St. Louis

A live treemap of the largest VC rounds. Each cell is one round into St. Louis-headquartered companies, grouped by Dealroom sector.

Largest rounds in St. Louis - 2026

Every $15M+ VC round into St. Louis-headquartered companies in 2026, grouped by Dealroom sector.
- rounds · - raised
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VC investment

How much venture capital flows into St. Louis

VC investment into St. Louis-headquartered, VC-backed companies, broken down by round size, company location, sector and funding stage.

Academia

St. Louis's academic flywheel

Companies founded by university alumni or spun out of research, plus the institutions producing the most founders tied to St. Louis.

University-linked startup formation
57
University spinouts
631
Total alumni-founded companies
361
Of which startups (<$15M raised)
189
Breakouts ($15M-100M)
81
Scaleups ($100M+)

Location comparison

How St. Louis stacks up

Compare St. Louis with peers from the same country (United States) — switch between combined EV, EV growth, and a growth × size view. Expand the table for the full ranking.

$60B
$59.4B
$54.3B
$43.4B
$41.6B
$39B
$37.2B
St. Louis
$18.1B

Combined enterprise value of each ecosystem.

Get the full St. Louis ecosystem on Dealroom

Live company-by-company deal flow, full cap tables, founder pedigrees, hiring signals and revenue trajectories.