St. Louis
Metro area · United States · Pop. 2.8M
* C→Unicorn and Unicorn→Decacorn rates are derived from current counts (no founding-cohort data); the four mid-funnel rates use Dealroom's cohort tracking.
Largest rounds
Largest funding rounds in St. Louis
A live treemap of the largest VC rounds. Each cell is one round into St. Louis-headquartered companies, grouped by Dealroom sector.
Largest rounds in St. Louis - 2026
VC investment
How much venture capital flows into St. Louis
VC investment into St. Louis-headquartered, VC-backed companies, broken down by round size, company location, sector and funding stage.
Academia
St. Louis's academic flywheel
Companies founded by university alumni or spun out of research, plus the institutions producing the most founders tied to St. Louis.
Location comparison
How St. Louis stacks up
Compare St. Louis with peers from the same country (United States) — switch between combined EV, EV growth, and a growth × size view. Expand the table for the full ranking.
Combined enterprise value of each ecosystem.
Top cities in United States ranked by combined EV. St. Louis's row is highlighted (#12).
| # | Ecosystem | Combined EV | EV growth | Unicorns | VC invested | Tracked startups |
|---|---|---|---|---|---|---|
| 1 | Bay Area | $20T | 8.0× | 866 | $156B | 24.5K |
| 2 | Seattle | $2.9T | 4.4× | 68 | $6.6B | 2,966 |
| 3 | Austin | $2T | 13.9× | 62 | $8.1B | 2,649 |
| 4 | New York City | $1.6T | 5.1× | 329 | $32.3B | 16.6K |
| 5 | Boston | $1.2T | 4.5× | 211 | $13.4B | 6,323 |
| 6 | Los Angeles | $1.2T | 5.7× | 158 | $16.3B | 8,592 |
| 7 | Miami | $673B | 12.8× | 40 | $2.6B | 2,865 |
| 8 | San Diego | $330B | 5.1× | 64 | $3.4B | 2,224 |
| 9 | Chicago | $266B | 3.7× | 52 | $2.2B | 2,833 |
| 10 | Washington DC | $265B | 3.3× | 55 | $3.5B | 2,343 |
| 11 | Dallas | $203B | 3.8× | 35 | $1.6B | 2,033 |
| 42 | St. Louis | $19B | 3.5× | 4 | $316.8M | 542 |
More data
Explore Dealroom data →Get the full St. Louis ecosystem on Dealroom
Live company-by-company deal flow, full cap tables, founder pedigrees, hiring signals and revenue trajectories.