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Metro area · North America

San Diego

Metro area · United States · Pop. 3.2M · #17 city by EV

A public taster of the full San Diego ecosystem on Dealroom — request a demo for live deal flow, founder pedigrees, AI-talent maps, and the full cap table for every company below.

$399B+44%
Combined startup EV
$3.3B
VC invested (last 12mo)
2,230
Tracked startups
#8/ 199
Unicorns per 1M people · cities rank
🦄 Unicorns
52
52 live $1B+ companies
💎 Decacorns
3
$10B+ tier
🐎 Thoroughbreds
34
Top 1% growth · $500M+

Enterprise value · 2015–2025

San Diego grew 8.0× since 2015

Combined enterprise value of every tracked startup headquartered in San Diego that's still operating today — public and private companies combined, totalled by founding-year cohort.

0 $100B $200B $300B $400B San Diego · $400B 2015 2018 2021 2024 2025

Adjacent cities by EV

Startup funnel

San Diego's power-law funnel

From the first cheque written to a $10B+ outcome. Each arrow shows what fraction of companies at one stage graduate to the next, tracked by founding cohort.

Pre-Seed
382
Seed
352
Series A
388
Series B
253
Series C
187
Unicorn
48
Decacorn
4

* C→Unicorn and Unicorn→Decacorn rates are derived from current counts (no founding-cohort data); the four mid-funnel rates use Dealroom's cohort tracking.

Notable companies

Top private companies in San Diego

Up to 20 names per tier from Dealroom's tracked dataset. Decacorns are valued $10B+, unicorns $1B+, thoroughbreds have crossed $100M in revenue.

Decacorns $10B+ valuation 4
DexcomIlluminaShield AIBiosplice Therapeutics
Unicorns $1B+ valuation 48
Mirati TherapeuticsAmbrxUnconventional AIErascaVividion TherapeuticsPrometheus BiosciencesBelite BioLivsmedGenMark DiagnosticsNetraDyneAuspex PharmaceuticalsTuSimpleAnaptysBioVentyx BiosciencesAragon PharmaceuticalsClickUpNerio TherapeuticsSantarusVuoriRayzeBio+28 more
Thoroughbreds+ $100M+ revenue 27
Arkeia SoftwareDexcomIlluminaACADIA PharmaceuticalsTandem Diabetes CareVuoriMedia DoMirum PharmaceuticalsMaxLinearSeismicClickUpShield AIAnaptysBioMaravai Life SciencesInseegoCueDrataARS PharmaceuticalsArcturus TherapeuticsGossamer Bio

Academia

San Diego's academic flywheel

Companies founded by university alumni or spun out of research, plus the institutions producing the most founders tied to San Diego.

University-linked startup formation
56
University spinouts
1,050
Total alumni-founded companies
598
Of which startups (<$15M raised)
312
Breakouts ($15M-100M)
140
Scaleups ($100M+)

Vs. similarly-sized ecosystems

How San Diego stacks up

Peers chosen from the same country (United States), sized closest to San Diego by combined EV. The scatter plots growth × current size — outliers in the upper-right are ecosystems compounding fastest.

Combined enterprise value
$1.2T
$1.2T
$619B
San Diego
$399B
$256B
$195B
$143B
EV growth (5-yr ×) vs current EV
peer median 4.0× 1.1× 74.1× 147.0× $5.1B $321B $20.1T EV growth (5yr ×) Combined enterprise value (log) Bay Area Seattle Austin New York City Boston Los Angeles Miami Washington DC Chicago Dallas Philadelphia Research Triangle Phoenix Atlanta Salt Lake City Denver Minneapolis–Saint Paul Houston San Diego

Top overview

United States — top cities

Top cities in United States ranked by combined EV. San Diego's row is highlighted.

# Ecosystem Combined EV 5-yr EV growth Unicorns VC invested Tracked startups
1 Bay Area $20.1T 7.9× 777 $157B 24.3K
2 Seattle $3.1T 10.6× 68 $6.6B 2,935
3 Austin $2T 14.0× 56 $8.1B 2,481
4 New York City $1.7T 5.3× 296 $31.2B 16.4K
5 Boston $1.2T 4.7× 185 $13.6B 6,194
6 Los Angeles $1.2T 5.8× 133 $18.3B 8,432
7 Miami $619B 12.9× 33 $2.9B 2,736
8 San Diego $399B 6.2× 52 $3.3B 2,230
9 Washington DC $317B 4.2× 45 $3.5B 2,318
10 Chicago $256B 3.5× 50 $2.1B 2,924
11 Dallas $195B 3.9× 31 $1.5B 1,866
12 Philadelphia $143B 6.8× 13 $2.1B 2,109

Premium analytics

What we don't show on this page (yet)

Sector breakdowns, founder origins, AI-talent leaderboards and live deal flow are gated to logged-in Dealroom users. Book a demo to access the full San Diego dataset — or see a sample on the Dealroom app.

Sector breakdown
Where San Diego's unicorns concentrate
Fintech
AI / Enterprise SW
Health Tech
Biotech
Cybersecurity
Consumer
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Capital autonomy
San Diego's domestic vs foreign capital mix
% domestic VC by stage
Cross-border lead investors
Sovereign-fund participation
Foreign-LP exposure
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Recent momentum
San Diego's VC investment trajectory by stage
2024 vs 2025 by stage
Round-size trends
Stage-conversion deltas
Quarterly velocity
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Founder origins
Where San Diego's startup founders come from
By country of origin
Per capita
Top universities
Top alumni-factory companies
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AI talent
Top employers of AI talent in San Diego
Core AI roles
Frontier AI roles
YoY hiring growth
Senior + lead engineers
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Deal flow
Live deal flow & funding rounds in San Diego
New rounds last 30 days
Stage breakdown
Active investors
Round-size trends
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