Product Reports Resources Pricing Login Book a demo
Investor profile

Polaris Partners

Private Equity, Venture Capital · Founded 1996 · Boston, United States

Website ↗LinkedIn ↗X / Twitter ↗Dealroom ↗

Building relationships with technology and healthcare industry visionaries across all stages

354 portfolio companies Private Equity, Venture Capital · $19B invested · 666 investments · Investor rank #129 · Last investment 6/2026
Portfolio companies 354 ↑ 10% 5y
Decacorns 3
Thoroughbreds 25
Power Law #181Investor Ranking · Global · 2026 · Top 1%
Featured in
News Cirrus Therapeutics raises $14.7M seed for eye gene therapy Aug 4, 2026 News UpDoc debuts first FDA-cleared clinical AI platform, closes $18M seed round Jun 25, 2026 News Tavo Biotherapeutics raises $17M Series A for glaucoma and retinal disease therapies Jun 2, 2026
Estimated holdings

Polaris Partners’ biggest current holdings.

An estimate of Polaris Partners’ largest live positions — disclosed shareholding × Dealroom’s latest valuation — across 3 companies where Polaris Partners is a named shareholder, worth about $597M in estimated equity value.

#CompanyEst. stakeValuationEst. value
  1. 1 AutomatticTelecom · Unicorn 6.5% $7.5B $488M
  2. 2 FloQastFintech · Unicorn 4% $1.6B $64M
  3. 3 FreenomeHealth · Unicorn 3% $1.5B $45M

Estimated value = Polaris Partners’ disclosed ownership % × Dealroom’s latest company valuation; direct named stakes only, exited positions excluded. Figures are indicative, not reported marks. See the underlying cap tables on Dealroom →

Exits

Polaris Partners’ biggest exits.

Portfolio companies that IPO’d or were acquired at $1B+, with the valuation recorded at exit and — for those still public — their value today. Exit events come from each company’s funding-round history; entry stage from Polaris Partners’ transaction record.

Alnylam Pharmaceuticals
$114M IPO · 2004
Entered Series B+Now $25BHealth
Akamai
IPO · 1999
Entered Series ANow $21BSecurity
Acceleron Pharma
$385M IPO · 2013
Entered Series B+Now $12BHealth
Momenta Pharmaceuticals
$35M IPO · 2004
Entered Series ANow $6.5BHealth
Scholar Rock
$350M IPO · 2018
Entered SeedNow $5.6BHealth
Impinj
IPO · 2016
Entered Series B+Now $4.6BSemiconductors
GoTo | LogMeIn
$342M IPO · 2009
Entered Series B+Now $4.3BSecurity
One Medical
$1.7B IPO · 2020
Entered Series B+Now $3.7BHealth
Morphic Therapeutic
$429M IPO · 2019
Entered Series ANow $2.2BHealth
Iora Health
$2.1B acquisition · 2021
Entered Series B+Health
Capstan Therapeutics
$2.1B acquisition · 2025
Entered Series AHealth
Candid Therapeutics
$2.0B acquisition · 2026
Entered Series B+Health
Portfolio analysis

Where Polaris Partners’ portfolio is concentrated.

Distribution of portfolio companies by headquarters country, sector, entry stage and current growth stage. Across all 354 portfolio companies. "Stage entered" is the first priced round the investor joined, derived from the investor’s transaction history.

By countryCount
  1. USA325
  2. Ireland6
  3. UK5
  4. Singapore4
  5. Netherlands3
  6. Belgium2
  7. Israel2
  8. Canada1
  9. Denmark1
  10. France1
  11. Lithuania1
  12. Rwanda1
By sectorCount
  1. Health183
  2. Enterprise Software47
  3. Marketing28
  4. Media21
  5. Security17
  6. Fintech16
  7. Telecom11
  8. Energy9
  9. Food9
  10. Wellness Beauty9
  11. Transportation8
  12. Legal6
By stage enteredCount
  1. Series A159
  2. Series B+126
  3. Seed52
By growth stageCount
  1. Breakout Stage150
  2. Late Growth121
  3. Early Growth76
  4. Mature7
Portfolio market map

Inside Polaris Partners’ portfolio.

The 60 highest-funded portfolio companies, of 354 tracked.

Johnson & Johnson Innovative Medicine
Health
Freenome
Health · Unicorn
$1.1B
Automattic
Telecom · Unicorn
$7.5B
Gossamer Bio
Health
$205M
Neumora Therapeutics
Health
$212M
Cardurion Pharmaceuticals
Health · Unicorn
$1.0B
One Medical
Health · Unicorn
$3.7B
Kallyope
Health · Unicorn
$1.2B
Invivyd
Health · Unicorn
$1.8B
EGenesis
Health
$764M
Genuity Science
Health
$100M
Tectonic Therapeutic
Health
$305M
Ocular Therapeutix
Health · Unicorn
$1.3B
Candid Therapeutics
Health · Unicorn
$2.0B
Iora Health
Health · Unicorn
$2.1B
Capstan Therapeutics
Health · Unicorn
$2.1B
Leyden Labs
Health
$176M
Editas Medicine
Health
$306M
ByHeart
Food
$475M
Ironwood Pharmaceuticals
Health
$990M
Tome Biosciences
Health
$512M
FloQast
Fintech · Unicorn
$1.6B
Ajax Health
Health
$340M
Internet Brands | CarsDirect.com
Health · Unicorn
$1.1B
Vets First Choice
Health
$892M
Lyndra Therapeutics (Formerly Lyndra)
Health
$404M
Triveni Bio
Health
$575M
Dewpoint Therapeutics
Health
$600M
Kronos Bio
Health
PathAI
Health
$750M
Tessa Therapeutics
Health
$504M
Syros Pharmaceuticals
Health
$1.9M
AgBiome
Food
$464M
XANT.ai
Enterprise Software · Unicorn
$1.6B
InsideSales
Marketing · Unicorn
$1.5B
Akili
Gaming
$31M
SQZ Biotech
Health
Cardiac Dimensions
Health
$212M
Proof
Legal
$760M
Seismic Therapeutic
Health
$484M
e-Rewards
Marketing
$60M
Tropic
Food
$420M
Quartet Health
Health
$240M
TRex Bio
Health
$420M
Selecta Biosciences
Health
$84M
Thirty Madison
Health
$500M
Nanosys
Semiconductors
$100M
Nomad Health
Health
$525M
Jnana
Health
$428M
Fire1 | Norm.
Health
$480M
Soufflé Therapeutics
Health
$800M
Cohere Health
Health
$360M
Alector
Health
$7.9M
Cardlytics
Fintech
$172M
Amunix
Health · Unicorn
$1.0B
Camp4 Therapeutics
Health
$400M
EpiBiologics
Health
$428M
T2 Biosystems
Health
$23M
Neuronetics
Health
$209M
OM1
Health
$340M
Portfolio founders

Where Polaris Partners’ portfolio founders come from.

146 founders across the 100 highest-funded portfolio companies — by current location, university attended, and the companies they worked at before founding. Sourced from the founder records the API links to each portfolio company.

LocationCount
  1. United States113
  2. Netherlands8
  3. United Kingdom4
  4. Singapore3
  5. Australia1
  6. China1
  7. France1
  8. Germany1
  9. Peru1
  10. Sweden1
UniversityCount
  1. Harvard University15
  2. Massachusetts Institute of Technology9
  3. Harvard Medical School8
  4. University of California, Berkeley5
  5. Yale University5
  6. Cornell University4
  7. Harvard Business School4
  8. Stanford University4
  9. Caltech, California Institute of Technology3
  10. Dartmouth College3
Previous companyCount
  1. Biogen4
  2. Harvard Medical School4
  3. McKinsey & Company4
  4. Novartis4
  5. Harvard University3
  6. Janssen Vaccines3
  7. Massachusetts General Hospital3
  8. Massachusetts Institute of Technology3
  9. Alphabet | Google2
  10. Arsomedi2
How Polaris Partners stacks up

Similar investors.

Peers the API surfaces as most similar by portfolio shape, with Dealroom investor rank and portfolio scale.

NEA
Venture Capital · Menlo Park
#36 rank 1,186 companies $2.5T portfolio
Sequoia
Venture Capital · Menlo Park
#3 rank 1,919 companies $22T portfolio
Bpifrance
Sovereign Wealth Fund · Maisons-Alfort
#92 rank 1,363 companies $165B portfolio
Y Combinator
Accelerator · San Francisco
#64 rank 7,094 companies $1.9T portfolio
Khosla Ventures
Venture Capital · Menlo Park
#53 rank 854 companies $1.9T portfolio
Plug and Play
Venture Capital · Sunnyvale
#366 rank 1,576 companies $294B portfolio
Intel Capital
Corporate · Santa Clara
#76 rank 983 companies $1.1T portfolio
Techstars
Accelerator · New York City
#847 rank 2,278 companies $250B portfolio
Key people

Key people at Polaris Partners.

Terrance McGuire
Terrance McGuire
Founder
 John Gannon
John Gannon
CFO
 Brian Chee
Brian Chee
Managing Partner
 Dave Barrett
Dave Barrett
General Partner
 Eileen McGuire
Eileen McGuire
Partner
 Leah Gilmore-Paquette
Leah Gilmore-Paquette
Director
 Gary Swart
Gary Swart
General Partner
 Pat Kinsel
Pat Kinsel
Entrepreneur In Residence
 Brendan Hannigan
Brendan Hannigan
Entrepreneur
 Alexandra Cantley
Alexandra Cantley
Partner
 David Barrett
David Barrett
Managing Partner
 Steve Arnold
Steve Arnold
Co-Founder and Partner Emeritus
Source: Dealroom next-gen API — investor team endpoint.
Figures on this page are sourced live from the Dealroom next-gen API, joined with Dealroom’s cap-table dataset (estimated holdings) and the Power Law Investor Ranking. News in “Featured in” is drawn from Dealroom’s own coverage — the stories that name this investor, not only those it is the subject of. Market sentiment is omitted until the API exposes it.