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Polaris Partners

Private Equity, Venture Capital · Founded 1996 · Boston, United States

#181 Investor Ranking 2026 Top 1% of investors worldwide

Building relationships with technology and healthcare industry visionaries across all stages

354 Portfolio companies+10% in 5 years
26 Unicorns
3 Decacorns
666 Investments
Aug 2026 Last investment
02 · Biggest holdings

Polaris Partners’ biggest current holdings.

Polaris Partners is a named shareholder in 3 companies. Dealroom estimates those stakes are worth about $597M in total — the disclosed percentage × each company’s latest valuation. The 3 biggest are listed below.

#CompanyEst. stakeValuationEst. value
  1. 1 AutomatticTelecom · Unicorn 6.5% $7.5B $488M
  2. 2 FloQastFintech · Unicorn 4% $1.6B $64M
  3. 3 FreenomeHealth · Unicorn 3% $1.5B $45M

Estimated value = Polaris Partners’ disclosed ownership % × Dealroom’s latest company valuation; direct named stakes only, exited positions excluded. Figures are indicative, not reported marks. See the underlying shareholder registers on Dealroom →

03 · Exits

Polaris Partners’ biggest exits.

Portfolio companies that IPO’d or were acquired at $1B+, with the valuation recorded at exit and — for those still public — their value today. Exit events come from each company’s funding-round history; entry stage from Polaris Partners’ transaction record.

$114M IPO · 2004
Entered Series B+Now $27BHealth
IPO · 1999
Entered Series ANow $22BSecurity
$385M IPO · 2013
Entered Series B+Now $12BHealth
$35M IPO · 2004
Entered Series ANow $6.5BHealth
Scholar Rock
$350M IPO · 2018
Entered SeedNow $6.2BHealth
IPO · 2016
Entered Series B+Now $5.7BSemiconductors
$342M IPO · 2009
Entered Series B+Now $4.3BSecurity
$1.7B IPO · 2020
Entered Series B+Now $3.7BHealth
Morphic Therapeutic
$429M IPO · 2019
Entered Series ANow $2.2BHealth
$2.1B acquisition · 2021
Entered Series B+Health
$2.1B acquisition · 2025
Entered Series AHealth
Candid Therapeutics
$2.0B acquisition · 2026
Entered Series B+Health
04 · Portfolio analysis

Where Polaris Partners’ portfolio is concentrated.

Distribution of portfolio companies by headquarters country, sector, entry stage and current growth stage. Across all 354 portfolio companies. "Stage entered" is the first priced round the investor joined, derived from the investor’s transaction history.

By countryCount
  1. USA332
  2. Ireland8
  3. UK5
  4. Singapore4
  5. Netherlands3
  6. Belgium2
  7. Israel2
  8. Canada1
  9. Denmark1
  10. France1
  11. Lithuania1
  12. Rwanda1
By sectorCount
  1. Health185
  2. Enterprise Software48
  3. Marketing29
  4. Media24
  5. Security17
  6. Fintech16
  7. Food11
  8. Telecom11
  9. Energy10
  10. Wellness Beauty9
  11. Transportation8
  12. Legal6
By stage enteredCount
  1. Series A159
  2. Series B+127
  3. Seed52
By growth stageCount
  1. Breakout Stage152
  2. Late Growth123
  3. Early Growth81
  4. Mature7
05 · Portfolio market map

Inside Polaris Partners’ portfolio.

The 60 highest-funded portfolio companies, of 354 tracked.

Johnson & Johnson Innovative Medicine
Health
Freenome
Health · Unicorn
$1.3B
Automattic
Telecom · Unicorn
$7.5B
Gossamer Bio
Health
$191M
Neumora Therapeutics
Health
$206M
Cardurion Pharmaceuticals
Health · Unicorn
$1.0B
One Medical
Health · Unicorn
$3.7B
Kallyope
Health · Unicorn
$1.2B
Invivyd
Health · Unicorn
$1.8B
EGenesis
Health
$764M
Genuity Science
Health
$100M
Tectonic Therapeutic
Health
$383M
Ocular Therapeutix
Health · Unicorn
$1.5B
Candid Therapeutics
Health · Unicorn
$2.0B
Iora Health
Health · Unicorn
$2.1B
Capstan Therapeutics
Health · Unicorn
$2.1B
Leyden Labs
Health
$176M
Editas Medicine
Health
$246M
ByHeart
Food
$475M
Ironwood Pharmaceuticals
Health · Unicorn
$1.0B
Tome Biosciences
Health
$512M
FloQast
Fintech · Unicorn
$1.6B
Ajax Health
Health
$340M
Internet Brands | CarsDirect.com
Health · Unicorn
$1.1B
Vets First Choice
Health
$892M
Lyndra Therapeutics (Formerly Lyndra)
Health
$404M
Triveni Bio
Health
$575M
Dewpoint Therapeutics
Health
$600M
Tropic
Food
$420M
Kronos Bio
Health
PathAI
Health
$750M
Tessa Therapeutics
Health
$504M
Syros Pharmaceuticals
Health
$1.9M
AgBiome
Food
$464M
InsideSales
Marketing · Unicorn
$1.5B
XANT.ai
Enterprise Software · Unicorn
$1.6B
Akili
Gaming
$31M
SQZ Biotech
Health
Cardiac Dimensions
Health
$212M
Proof
Legal
$760M
Seismic Therapeutic
Health
$484M
e-Rewards
Marketing
$60M
Quartet Health
Health
$240M
TRex Bio
Health
$420M
Selecta Biosciences
Health
$127M
Thirty Madison
Health
$500M
Nanosys
Semiconductors
$100M
Nomad Health
Health
$525M
Jnana
Health
$428M
Fire1 | Norm.
Health
$480M
Soufflé Therapeutics
Health
$800M
Cohere Health
Health
$360M
Alector
Health
$59M
Cardlytics
Fintech
$183M
Amunix
Health · Unicorn
$1.0B
Camp4 Therapeutics
Health
$400M
EpiBiologics
Health
$428M
T2 Biosystems
Health
$23M
Neuronetics
Health
$238M
Cyclerion Therapeutics
Health
$15M
06 · Portfolio founders

Where Polaris Partners’ portfolio founders come from.

144 founders across the 100 highest-funded portfolio companies — by current location, university attended, and the companies they worked at before founding. Sourced from the founder records the API links to each portfolio company.

LocationCount
  1. United States114
  2. Netherlands8
  3. United Kingdom4
  4. Australia1
  5. China1
  6. Germany1
  7. Peru1
  8. Singapore1
  9. Sweden1
  10. Switzerland1
UniversityCount
  1. Harvard University14
  2. Harvard Medical School8
  3. Massachusetts Institute of Technology8
  4. University of California, Berkeley6
  5. Yale University5
  6. Cornell University4
  7. Harvard Business School4
  8. Stanford University4
  9. Caltech, California Institute of Technology3
  10. Leiden University3
Previous companyCount
  1. Biogen4
  2. Harvard Medical School4
  3. McKinsey & Company4
  4. Novartis4
  5. Harvard University3
  6. Janssen Vaccines3
  7. Massachusetts General Hospital3
  8. Massachusetts Institute of Technology3
  9. Alphabet | Google2
  10. Arsomedi2