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Investor profile

Casdin Capital

Venture Capital · Founded 2012 · New York City, United States

Casdin CapitalCasdin Capital | Financing Next Generation Life Science Innovation

138 portfolio companies Venture Capital · $21B invested · 216 investments · Investor rank #120 · Last investment 6/2026
Portfolio companies 138 ↑ 20% 5y
Decacorns 4
Thoroughbreds 20
01 · Biggest holdings

Casdin Capital’s biggest current holdings.

The most valuable companies Casdin Capital still holds — unicorns and thoroughbreds it has backed, ordered by Dealroom’s latest valuation. Companies that have been acquired or gone public are in Exits instead. Where a cap table names Casdin Capital directly, the stake and its estimated value are shown too.

#CompanyEst. stakeValuationEst. value
  1. 1 Lyra HealthUnicorn · Health · USA $5.8B
  2. 2 Treeline BiosciencesUnicorn · Health · USA $2.1B
  3. 3 InsitroUnicorn · Health · USA $1.6B
  4. 4 Formation BioUnicorn · Health · USA $1.5B
  5. 5 KallyopeUnicorn · Health · USA $1.2B
  6. 6 Umoja BiopharmaUnicorn · Health · USA $1.1B
  7. 7 LetsGetCheckedUnicorn · Health · USA 10.5% $1.0B $105M
  8. 8 Thyme CareUnicorn · Health · USA $1.0B
  9. 9 Komodo HealthHealth · USA $800M

Estimated value = Casdin Capital’s disclosed ownership % × Dealroom’s latest company valuation; direct named stakes only, exited positions excluded. Figures are indicative, not reported marks. Casdin Capital also appears inside investor groups in Lyra Health, where a standalone stake isn’t disclosed. See the underlying cap tables on Dealroom →

02 · Exits

Casdin Capital’s biggest exits.

Portfolio companies that IPO’d or were acquired at $1B+, with the valuation recorded at exit and — for those still public — their value today. Exit events come from each company’s funding-round history; entry stage from Casdin Capital’s transaction record.

$1.4B IPO · 2020
Entered Series B+Now $41BHealth
$2.0B IPO · 2019
Now $18BHealth
IPO · 2015
Entered Series ANow $13BHealth
IPO · 2020
Entered Series B+Now $12BHealth
$398M IPO · 2015
Entered Series B+Now $8.3BHealth
$500M IPO · 2013
Entered Series B+Now $5.3BHealth
Parabilis Medicines
$2.4B IPO · 2026
Entered Series B+Now $4.8BHealth
$167M IPO · 2021
Entered Series B+Now $4.1BHealth
$3.7B IPO · 2021
Entered Series B+Now $2.2BHealth
$3.6B IPO · 2021
Entered Series ANow Health
$3.5B IPO · 2021
Entered Series B+Now $150MHealth
$1.7B IPO · 2020
Entered Series B+Now $3.5BHealth
03 · Portfolio analysis

Where Casdin Capital’s portfolio is concentrated.

Distribution of portfolio companies by headquarters country, sector, entry stage and current growth stage. Across all 138 portfolio companies. "Stage entered" is the first priced round the investor joined, derived from the investor’s transaction history.

By countryCount
  1. USA130
  2. France5
  3. Canada4
  4. China3
  5. UK3
  6. Netherlands2
  7. Switzerland2
  8. South Korea1
By sectorCount
  1. Health143
  2. Enterprise Software4
  3. Security2
  4. Chemicals1
  5. Education1
  6. Engineering and Manufacturing Equipment1
  7. Fashion1
  8. Fintech1
  9. Food1
  10. Media1
  11. Robotics1
  12. Transportation1
By stage enteredCount
  1. Series B+79
  2. Series A48
  3. Seed6
By growth stageCount
  1. Late Growth112
  2. Breakout Stage25
  3. Early Growth12
  4. Mature1
04 · Portfolio market map

Inside Casdin Capital’s portfolio.

The 60 highest-funded portfolio companies, of 138 tracked.

EQRx
Health
Clover Health
Health · Unicorn
$2.2B
Treeline Biosciences
Health · Unicorn
$2.1B
23andMe
Health
$150M
SomaLogic
Health
Parabilis Medicines
Health · Unicorn
$4.8B
BridgeBio
Health · Decacorn
$18B
Lyra Health
Health · Unicorn
$5.8B
Exscientia
Health
$688M
Maze Therapeutics
Health
$140M
Insitro
Health · Unicorn
$1.6B
Century Therapeutics
Health
$272M
LetsGetChecked
Health · Unicorn
$1.0B
Recursion Pharma
Health · Unicorn
$1.3B
Sema4
Health · Unicorn
$2.0B
Relay Therapeutics
Health · Unicorn
$3.5B
Avidity Biosciences
Health · Decacorn
$12B
Formation Bio
Health · Unicorn
$1.5B
Komodo Health
Health
$800M
Kallyope
Health · Unicorn
$1.2B
Neurogene
Health
$429M
Enjoy
Transportation · Unicorn
$1.2B
Scorpion Therapeutics
Health · Unicorn
$2.5B
Constellation Pharmaceuticals
Health · Unicorn
$1.7B
Helix
Health · Unicorn
$1.0B
Vividion Therapeutics
Health · Unicorn
$1.5B
Ventus Therapeutics
Health
$280M
Thrive Earlier Detection
Health · Unicorn
$2.2B
Verve Therapeutics
Health
$566M
Umoja Biopharma
Health · Unicorn
$1.1B
Genomatica
Wellness Beauty
$472M
Tango Therapeutics
Health · Unicorn
$4.1B
A2biotherapeutics
Health
$320M
Prime Medicine
Health
$615M
DNA Script
Health
$825M
Sonoma Biotherapeutics
Health · Unicorn
$1.1B
Leyden Labs
Health
$176M
Editas Medicine
Health
$246M
LianBio
Health
Orchard Therapeutics
Health
$303M
Nautilus
Health
$59M
ORIC Pharmaceuticals
Health · Unicorn
$1.1B
Adlai Nortye
Health
$874M
Flare Therapeutics
Health
$340M
Verana Health
Health
$600M
Amplifybio
Health
$200M
Taysha Gene Therapies
Health · Unicorn
$1.7B
Kronos Bio
Health
Orbital Therapeutics
Health · Unicorn
$1.5B
NiKang Therapeutics
Health
$382M
Gritstone Oncology
Health
$1.6M
Chroma Medicine
Health
$540M
Generation Bio
Health
Septerna
Health · Unicorn
$1.4B
Tenaya Therapeutics
Health
$89M
IDRx
Health · Unicorn
$1.0B
Paige.AI
Health
$81M
Moma Therapeutics
Health
$600M
City Therapeutics
Health
$675M
Thyme Care
Health · Unicorn
$1.0B
05 · Portfolio founders

Where Casdin Capital’s portfolio founders come from.

197 founders across the 100 highest-funded portfolio companies — by current location, university attended, and the companies they worked at before founding. Sourced from the founder records the API links to each portfolio company.

LocationCount
  1. United States159
  2. United Kingdom9
  3. France4
  4. Netherlands4
  5. South Korea4
  6. Germany2
  7. Ireland1
  8. Israel1
UniversityCount
  1. Massachusetts Institute of Technology12
  2. Stanford University11
  3. Harvard University10
  4. Harvard Medical School8
  5. Harvard Business School5
  6. University of California, Berkeley5
  7. University of Cambridge5
  8. Brown University4
  9. Columbia University3
  10. Leiden University3
Previous companyCount
  1. Dana-Farber Cancer Institute6
  2. Harvard University5
  3. Massachusetts General Hospital5
  4. Broad Institute4
  5. McKinsey & Company4
  6. Merck & Co.4
  7. Stanford University4
  8. Stanford University School of Medicine4
  9. Third Rock Ventures4
  10. Biogen3