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Zafgen

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A biopharmaceutical company that develops obesity therapeutics.

Cambridge, United StatesFounded 2005Biotech & Life Sciences
Valuation $250–500M Last recorded · 2026
Revenue $1–10M Latest reported FY
Headcount <100 Current team size
Total funding $100–500M Disclosed equity funding
Unlock exact values This page shows ranges. Dealroom has the exact numbers for Zafgen and the history behind them.

About Zafgen

Zafgen, now part of Larimar Therapeutics, is a biopharmaceutical company dedicated to developing innovative therapies for rare metabolic diseases. The company primarily targets conditions such as Prader-Willi syndrome and other genetic disorders that result in severe metabolic dysfunction. Operating in the highly specialized field of rare disease treatment, Zafgen serves a niche market of patients with limited therapeutic options. The business model revolves around the research, development, and commercialization of novel drug candidates. Revenue is generated through the successful development and subsequent licensing or sale of these therapies to larger pharmaceutical companies or directly to healthcare providers. Zafgen's strategic focus on rare diseases allows it to benefit from orphan drug designations, which can provide market exclusivity and financial incentives.

Source: Dealroom company data

At a glance

Status
Operational
Founded
2005
Headquarters
Cambridge, United States
Employees
81
Open positions
45
Dealroom signal
62.6/100
Industry
Health
Sub-industry
Pharmaceutical, BioTechnology
Sector
Biotech & Life Sciences, Biotechnology, Weight Management, Nutrition, Spinout, Metabolism, Biotech and Pharma, DT and LS, science-based
Business model
Manufacturing
Client focus
b2b

Funding history

9 recorded events

Company financing events and reported valuations.

Deal typeDateAmountValuationInvestorsSource
IPOOther financing Jun 2014 $0 — Undisclosed —
DEBTDebt Apr 2014 $20M — Midcap Financial —
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Financials

Revenue, earnings and profit over time

Revenue, earnings and other financial measures where available. Years marked “E” are estimates.

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Growth signals

Zafgen website traffic

Latest recorded traffic for Zafgen is 250 monthly website visits, down 80.8% over the last three months. Zafgen's team grew 1.3% over the past year.

Latest monthly visits250 3-month web change-80.8% 1-year team growth+1.3%
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Similar companies

Closest operating peers by Dealroom taxonomy

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Showing 8 of the closest matchesCompare every metric →

Investments and acquisitions

Capital deployed

Recent portfolio relationships for companies that also act as investors or acquirers.

Investors

10 investors on the cap table

From Dealroom's funding and investor records, grouped by the round each investor first entered.

Series A3 investors entered at this stage

Series B and later5 investors entered at this stage

Other known investors2 additional known investors

  • Children’s Hospital Boston
  • Massachusetts Institute of Technology
Team profiled 10 named & role-tagged
Founders Hidden — book a demo/100 quality score
Key operators 6 quality Hidden — book a demo/100
Potential founders Hidden — book a demo likely future founders
Startup mafia Hidden — book a demo alumni-founded startups
Talent movements Hidden — book a demo in · Hidden — book a demo out past 12 months

Source: Dealroom Talent Intelligence.

Global footprint

Workforce and web traffic by country
Workforce by country
2 countries with
team presence
🇺🇸 United States96.9%
🇧🇪 Belgium3.1%
2 countries shown

Market sentiment

Posts on X, past 7 days

An AI-synthesised read of the highest-engagement posts about Zafgen on X, ranked by likes and reposts, corporate channels excluded.

Reading the room on X — pulling top posts and synthesizing themes…

Source: X recent search ranked by engagement (likes + retweets) · Synthesis by Claude · Cached for 1 hour

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