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Investor profile

Third Rock Ventures

Venture Capital · Founded 2007 · Boston, United States

Discover, launch and build great companies based on bold ideas that meet at the intersection of science, strategy, business and medicine

72 portfolio companies Venture Capital · $8.6B invested · 138 investments · Investor rank #326 · Last investment 6/2026
Portfolio companies 72 ↑ 29% 5y
Decacorns 2
Thoroughbreds 10
01 · Exits

Third Rock Ventures’ biggest exits.

Portfolio companies that IPO’d or were acquired at $1B+, with the valuation recorded at exit and — for those still public — their value today. Exit events come from each company’s funding-round history; entry stage from Third Rock Ventures’ transaction record.

$1.4B IPO · 2020
Entered Series B+Now $41BHealth
IPO · 2015
Entered Series ANow $13BHealth
$398M IPO · 2015
Entered Series ANow $8.3BHealth
$443M IPO · 2017
Entered Series ANow $7.8BHealth
Global Blood Therapeutics
$350M IPO · 2015
Entered Series ANow $5.4BHealth
$500M IPO · 2013
Entered Series ANow $5.3BHealth
$167M IPO · 2021
Entered Series ANow $4.1BHealth
$1.7B IPO · 2020
Entered Series ANow $3.5BHealth
IPO · 2018
Entered Series ANow $2.7BHealth
$2.1B acquisition · 2020
Entered Series AHealth
IPO · 2020
Entered SeedNow $2.0BHealth
Candid Therapeutics
$2.0B acquisition · 2026
Entered Series B+Health
02 · Portfolio analysis

Where Third Rock Ventures’ portfolio is concentrated.

Distribution of portfolio companies by headquarters country, sector, entry stage and current growth stage. Across all 72 portfolio companies. "Stage entered" is the first priced round the investor joined, derived from the investor’s transaction history.

By countryCount
  1. USA70
  2. Belgium1
  3. Germany1
  4. Singapore1
By sectorCount
  1. Health71
  2. Enterprise Software1
  3. Fintech1
  4. Media1
By stage enteredCount
  1. Series A59
  2. Series B+10
  3. Seed3
By growth stageCount
  1. Late Growth54
  2. Breakout Stage15
  3. Early Growth3
  4. Mature1
03 · Portfolio market map

Inside Third Rock Ventures’ portfolio.

The 60 highest-funded portfolio companies, of 72 tracked.

Johnson & Johnson Innovative Medicine
Health
Maze Therapeutics
Health
$140M
Insitro
Health · Unicorn
$1.6B
Relay Therapeutics
Health · Unicorn
$3.5B
Constellation Pharmaceuticals
Health · Unicorn
$1.7B
Candid Therapeutics
Health · Unicorn
$2.0B
Thrive Earlier Detection
Health · Unicorn
$2.2B
Terremoto Biosciences
Health
$875M
Tango Therapeutics
Health · Unicorn
$4.1B
Editas Medicine
Health
$246M
Seaport Therapeutics
Health
$989M
Flare Therapeutics
Health
$340M
Rapport Therapeutics
Health · Unicorn
$1.8B
Septerna
Health · Unicorn
$1.4B
ARTBIO
Health
$528M
Moma Therapeutics
Health
$600M
Corvia Medical
Health
$220M
Neon Therapeutics
Health
$67M
Revolution Medicines
Health · Decacorn
$41B
Asher Bio
Health
$540M
Pliant Therapeutics
Health
CARGO Therapeutics
Health
Marea Therapeutics
Health
$570M
Abata Therapeutics
Health
$380M
Decibel Therapeutics
Health
$58M
Element Science
Health
$582M
Nurix
Health · Unicorn
$2.0B
CytomX Therapeutics
Health
$430M
Casma Therapeutics
Health
$293M
Bluebird bio
Health
$150M
Goldfinch Biopharma
Health
$400M
Magenta Therapeutics
Health
Clasp Therapeutics
Health
$600M
Fulcrum Therapeutics
Health
Synnovation Therapeutics
Health
$408M
Cedilla Therapeutics
Health
$288M
Zafgen
Health
$347M
KALA BIO
Health
$6.7M
MorphoSys
Health · Unicorn
$2.7B
Warp Drive Bio
Health
$238M
Rhythm Pharmaceuticals
Health · Unicorn
$7.8B
Merida Biosciences
Health
$484M
Agios Pharmaceuticals
Health · Unicorn
$1.3B
NinePoint Medical
Health
$123M
Blueprint Medicines
Health · Unicorn
$8.3B
TARIS Biomedical
Health
$100M
PanOptica
Health
$44M
Ambys Medicines
Health
$300M
Voyager Therapeutics
Health
$118M
Jounce Therapeutics
Health
Trace Neuroscience
Health
$404M
Foundation Medicine
Health · Unicorn
$5.3B
Alcresta
Health
$40M
SAGE Therapeutics
Health
$191M
Allena Pharmaceuticals
Health
$100M
Seventh Sense Biosystems
Health
$84M
Global Blood Therapeutics
Health · Unicorn
$5.4B
Afferent Pharmaceuticals
Health
$220M
Celsius Therapeutics
Health
$250M
Azalea Therapeutics
Health
$260M
04 · Portfolio founders

Where Third Rock Ventures’ portfolio founders come from.

103 founders across the 73 highest-funded portfolio companies — by current location, university attended, and the companies they worked at before founding. Sourced from the founder records the API links to each portfolio company.

LocationCount
  1. United States88
  2. Germany2
  3. United Kingdom2
  4. France1
  5. Singapore1
  6. Switzerland1
UniversityCount
  1. Harvard University9
  2. Massachusetts Institute of Technology5
  3. Harvard Medical School4
  4. Stanford University4
  5. Stanford University School of Medicine2
  6. University of Heidelberg2
  7. Wharton School of the University of Pennsylvania2
  8. Allegheny College1
  9. Bard College1
  10. Brown University1
Previous companyCount
  1. Third Rock Ventures5
  2. Pfizer4
  3. Biogen2
  4. Constellation Pharmaceuticals2
  5. Dana-Farber Cancer Institute2
  6. Genentech2
  7. Merck & Co.2
  8. Stanford University2
  9. Stanford University School of Medicine2
  10. Technology Transfer Center2