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Fulcrum Therapeutics

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Unlocking the mechanisms that regulate disease genes to develop a new generation of disease-modifying therapies

Cambridge, United StatesFounded 2016Biotech & Life Sciences
Valuation $291M Market cap · 2026

About Fulcrum Therapeutics

Fulcrum Therapeutics is a clinical-stage biopharmaceutical company dedicated to improving the lives of patients suffering from genetically defined diseases, particularly those with high unmet medical needs. The company focuses on rare diseases and employs a proprietary product engine to systematically identify and validate cellular drug targets. This technology aims to modulate gene expression to address the root causes of these diseases. Fulcrum Therapeutics collaborates with other industry leaders, such as MyoKardia, to discover novel targeted therapies for genetic cardiomyopathies. The company operates in the biopharmaceutical market, serving patients, healthcare providers, and research institutions. Its business model revolves around developing and commercializing innovative therapies, generating revenue through product sales, partnerships, and licensing agreements.

Source: Dealroom company data

At a glance

Status
Listed
Founded
2016
Headquarters
Cambridge, United States
Listing
IPO 2019
Sector
Biotech & Life Sciences

Investors

7 investors on the cap table

From Dealroom's funding and investor records, grouped by the round each investor first entered.

Series A7 investors entered at this stage

Team profiled 22 named & role-tagged
Founders Hidden — book a demo/100 quality score
Key operators 5 quality Hidden — book a demo/100
Potential founders Hidden — book a demo likely future founders
Startup mafia Hidden — book a demo alumni-founded startups
Talent movements Hidden — book a demo in · Hidden — book a demo out past 12 months

Source: Dealroom Talent Intelligence.

Global footprint

Workforce and web traffic by country
Workforce by country
2 countries with
team presence
🇺🇸 United States98.3%
🇳🇬 Nigeria1.7%
2 countries shown

Market sentiment

Posts on X, past 7 days

An AI-synthesised read of the highest-engagement posts about Fulcrum Therapeutics on X, ranked by likes and reposts, corporate channels excluded.

Reading the room on X — pulling top posts and synthesizing themes…

Source: X recent search ranked by engagement (likes + retweets) · Synthesis by Claude · Cached for 1 hour

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