OpenCRISPR-1, the world’s first ever open-source AI-generated human gene editor.
Nathan Benaiche (Air Street Capital) on LinkedIn wrote: Crispr therapeutics are potentially transformative, but the number of addressable diseases remains small, while the process is very expensive.
Profluent has created a gene editor that can generate diverse CRISPR-associated proteins never before seen in nature, including some that are over 400 mutations away from any known natural protein. It exhibited 95% editing efficiency across cell types.
They’re making this work freely available - no upfront charge, milestone payments, or royalties. Ever. Proud to have been their partner from Day One.
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- Profluent's new A.I. creates gene editors called OpenCRISPR-1, editing DNA for better disease control.
- Based on AI techniques like those in ChatGPT, analyzed biological data.
- Paper published by Berkeley startup; presentation at American Society of Gene and Cell Therapy soon.
- OpenCRISPR-1, inspired by Nobel-winning CRISPR, open-sourced for widespread experimentation.
- Technology could enable more precise genetic editing, potentially speeding up personalized medical treatments.
- Profluent's A.I. hasn't been clinically tested yet; effectiveness still under evaluation.
- Generative A.I. may rapidly improve, suggesting long-term potential for precise, tailored treatments.
Biorxiv paper: https://www.biorxiv.org/content/10.1101/2024.04.22.590591v1
