CuspAI closes $450M Series B at $2.6B valuation, backed by Bezos and UK Sovereign AI Fund
What's the deal? Cambridge-based startup CuspAI has closed a $450M Series B at a $2.6B valuation, co-led by US venture firms Kleiner Perkins and NEA. Backers include Jeff Bezos's Bezos Expeditions and Britain's Sovereign AI Venture Fund. It confirms and expands the deal reported in June, when term sheets had been signed at a $400M target; the round has now closed at $450M.
What's the endgame? Founded in 2024 by Chad EdwardsDealroom has a profile for this one. Try Dealroom → and Max WellingDealroom has a profile for this one. Try Dealroom →, CuspAI applies generative AI and molecular simulation to discover new materials. The round accompanies the launch of its AI Materials Foundry, a global network of data, labs, compute and scientific expertise, with more than 45 founding partners spanning the US, Asia-Pacific and Europe, including Nvidia, Meta, SamsungDealroom has a profile for this one. Try Dealroom → and Hyundai Motor GroupDealroom has a profile for this one. Try Dealroom →.
Who's in? New investors include Glade Brook Capital PartnersDealroom has a profile for this one. Try Dealroom →, Lux Capital, AMD VenturesDealroom has a profile for this one. Try Dealroom →, Tru Arrow PartnersDealroom has a profile for this one. Try Dealroom → and StepStone. Existing backers Temasek, Basis Set VenturesDealroom has a profile for this one. Try Dealroom →, Giant VenturesDealroom has a profile for this one. Try Dealroom →, Touring CapitalDealroom has a profile for this one. Try Dealroom → and Northzone also returned.
Why now? The valuation marks a sharp rise from $520M in September 2025, following a Series A of more than $100M less than a year earlier. CuspAI is expanding its footprint, adding a Singapore office to hubs in Cambridge, Amsterdam, Berlin, Tokyo and the US, and says the capital will scale computational infrastructure, grow its materials-research teams and bring its molecular-design platform to market.
The signal: The round shows deep-pocketed investors and industrial giants betting that AI can crack materials discovery, with a UK government fund and a US tech billionaire aligning behind the same wager.
Read more: The Guardian, Tech.eu, Silicon Republic
