Investor profile

Janus Henderson Investors

Other · Founded 1934 · Denver, United States

Website ↗LinkedIn ↗X / Twitter ↗Dealroom ↗

Helps its clients achieve their long-term financial goals

146 portfolio companies Other · $22B invested · 208 investments · Investor rank #110 · Last investment 7/2026

Portfolio companies 146 ↑ 67% 5y

Decacorns 3

Thoroughbreds 14 ↑ 29% 5y

Power Law #500Investor Ranking · Global · 2026 · Top 3%

Featured in

News Janus Henderson raises $350M for asset-backed credit fund, anchored by GE pension Aug 4, 2026

News Processa buys Vidya, raises ~$200M to push BTK inhibitor into three trials Jul 29, 2026

News LB Pharmaceuticals raises $150M to push lead drug into new indications Jul 29, 2026

Exits

Janus Henderson Investors’ biggest exits.

Portfolio companies that IPO’d or were acquired at $1B+, with the valuation recorded at exit and — for those still public — their value today. Exit events come from each company’s funding-round history; entry stage from Janus Henderson Investors’ transaction record.

Avidity Biosciences

IPO · 2020

Now $12BHealth

Crinetics Pharmaceuticals

$391M IPO · 2018

Now $10BHealth

Verona Pharma

$163M IPO · 2017

Entered Series ANow $10BHealth

Nuvalent

$191M IPO · 2021

Entered Series B+Now $8.5BHealth

Kymera Therapeutics

$174M IPO · 2020

Entered Series B+Now $8.2BHealth

BioNTech

$3.4B IPO · 2019

Entered Series ANow $7.0BHealth

Vaxcyte

$250M IPO · 2020

Entered Series B+Now $6.5BHealth

Centessa Pharmaceuticals

$1.9B IPO · 2021

Entered Series ANow $6.1BHealth

CG Oncology

$1.2B IPO · 2024

Entered Series B+Now $5.4BHealth

Metsera

$275M IPO · 2025

Entered Series B+Now $4.9BHealth

Mirion Technologies

$2.6B IPO · 2021

Now $4.5BSecurity

Parabilis Medicines

$2.4B IPO · 2026

Entered Series B+Now $4.5BHealth

Portfolio analysis

Where Janus Henderson Investors’ portfolio is concentrated.

Distribution of portfolio companies by headquarters country, sector, entry stage and current growth stage. Across all 146 portfolio companies. "Stage entered" is the first priced round the investor joined, derived from the investor’s transaction history.

By countryCount

USA129
UK6
Canada3
China2
India2
Denmark1
Germany1
Spain1
Switzerland1

By sectorCount

Health135
Transportation4
Energy3
Chemicals1
Consumer Electronics1
Dating1
Engineering and Manufacturing Equipment1
Gaming1
Media1
Real Estate1
Security1
Space1

By stage enteredCount

Series B+95
Series A25

By growth stageCount

Late Growth129
Breakout Stage16
Mature1

Portfolio market map

Inside Janus Henderson Investors’ portfolio.

The 60 highest-funded portfolio companies, of 146 tracked.

Transportation · Unicorn

Obsidian Therapeutics

Structure Therapeutics

Crinetics Pharmaceuticals

Health · Decacorn

$10B

Galecto | Damora Therapeutics

Health · Unicorn

$1.9B

Scorpion Therapeutics

Thrive Earlier Detection

Health · Unicorn

$2.2B

Angitia Biopharmaceuticals

Day One Biopharmaceuticals

Transportation · Unicorn

Sonoma Biotherapeutics

Arbor Biotechnologies

Gracell Biotechnologies

Diagonal Therapeutics

Health

$500M

Centessa Pharmaceuticals

Galvanize Therapeutics

Portfolio founders

Where Janus Henderson Investors’ portfolio founders come from.

158 founders across the 100 highest-funded portfolio companies — by current location, university attended, and the companies they worked at before founding. Sourced from the founder records the API links to each portfolio company.

LocationCount

United States130
United Kingdom4
Denmark3
Germany3
India3
China2
Israel2
Spain2
Australia1
France1

UniversityCount

Harvard University13
Massachusetts Institute of Technology10
Stanford University8
University of California, Berkeley7
Cornell University4
Dartmouth College3
Harvard Medical School3
University College London3
University of California, San Diego3
University of Cambridge3

Previous companyCount

Dana-Farber Cancer Institute7
McKinsey & Company7
Novartis7
Pfizer4
Scripps Translational Science Institute4
Amblyotech3
Biogen3
Brigham and Women's Hospital3
GSK3
Johnson & Johnson3

How Janus Henderson Investors stacks up

Similar investors.

Peers the API surfaces as most similar by portfolio shape, with Dealroom investor rank and portfolio scale.

Fidelity Investments

Private Equity · Boston

#7 rank 362 companies $6.1T portfolio

Temasek

Sovereign Wealth Fund · Singapore

#13 rank 376 companies $2.8T portfolio

Bpifrance

Sovereign Wealth Fund · Maisons-Alfort

#92 rank 1,363 companies $165B portfolio

Khosla Ventures

Venture Capital · Menlo Park

#53 rank 854 companies $1.9T portfolio

Corporate · San Francisco

#73 rank 422 companies $913B portfolio

Founders Fund

Venture Capital · San Francisco

#49 rank 611 companies $6.6T portfolio

Alumni Ventures

Venture Capital · Manchester

#186 rank 799 companies $200B portfolio

NEA

Venture Capital · Menlo Park

#36 rank 1,186 companies $2.5T portfolio

Key people

Key people at Janus Henderson Investors.

Source: Dealroom next-gen API — investor team endpoint.

Figures on this page are sourced live from the Dealroom next-gen API, joined with Dealroom’s cap-table dataset (estimated holdings) and the Power Law Investor Ranking. News in “Featured in” is drawn from Dealroom’s own coverage — the stories that name this investor, not only those it is the subject of. Market sentiment is omitted until the API exposes it.