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System1 Biosciences

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Neurotherapeutics company leveraging human brain models, scaled biology, and machine learning to discover novel drugs for complex brain diseases

San Francisco, United StatesFounded 2017Biotech & Life Sciences
Valuation $100–250M Last recorded · 2018
Headcount <100 Current team size
Total funding $10–50M Disclosed equity funding
Unlock exact values This page shows ranges. Dealroom has the exact numbers for System1 Biosciences and the history behind them.

About System1 Biosciences

System1 Biosciences, Inc. is a San Francisco-based neurotherapeutics company focused on discovering novel drugs for complex neurological and psychiatric diseases. The company employs phenotypic screening, which involves observing the effects of potential drugs on disease models, to identify promising therapeutic candidates. System1 Biosciences uses human stem cell-derived organoid models of brain tissue to capture disease-relevant genetics and target specific cell types, providing a more accurate representation of human brain diseases. Automation plays a crucial role in their approach, enabling scaled biology through automated culture and assay systems. This allows for high-throughput screening and more efficient drug discovery processes. Additionally, the company integrates advanced machine learning analytics to refine and augment the drug discovery process, from target identification to Investigational New Drug (IND) application. System1 Biosciences serves the pharmaceutical and biotechnology sectors, focusing on clients looking for innovative solutions to treat brain diseases. The company operates in the neurotherapeutics market, which is characterized by a high unmet need for effective treatments. The business model involves partnering with pharmaceutical companies and research institutions to develop and commercialize their drug candidates. Revenue is generated through research collaborations, licensing agreements, and milestone payments.

Source: Dealroom company data

At a glance

Status
Operational
Founded
2017
Headquarters
San Francisco, United States
Employees
6
Open positions
None listed
Dealroom signal
25.3/100
Industry
Health
Sub-industry
BioTechnology
Sector
Biotech & Life Sciences, Biotechnology, Neurology, Biotech and Pharma, Hard Tech, DT and LS, science-based
Business model
Manufacturing
Client focus
b2b

Funding history

1 recorded event

Company financing events and reported valuations.

Deal typeDateAmountValuationInvestorsSource
SERIES A✓Equity / VC Sep 2018 $25M $100M CRV —
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Growth signals

System1 Biosciences website traffic

Latest recorded traffic for System1 Biosciences is 280 monthly website visits, up 0% over the last three months. System1 Biosciences's team grew 0% over the past year.

Latest monthly visits280 3-month web change0% 1-year team growth0%
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Similar companies

Closest operating peers by Dealroom taxonomy

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Investments and acquisitions

Capital deployed

Recent portfolio relationships for companies that also act as investors or acquirers.

Investors

3 investors on the cap table

From Dealroom's funding and investor records, grouped by the round each investor first entered.

Series A1 investor entered at this stage

Other known investors2 additional known investors

  • Dolby Family Ventures
  • Longevity Fund
Employees 6 total headcount
Founders Hidden — book a demo/100 quality score
Key operators Hidden — book a demo quality score
Potential founders Hidden — book a demo likely future founders
Startup mafia Hidden — book a demo alumni-founded startups
Talent movements Hidden — book a demo in · Hidden — book a demo out past 12 months

Source: Dealroom Talent Intelligence.

Global footprint

Workforce and web traffic by country
Workforce by country
1 countries with
team presence
🇺🇸 United States100%
1 country shown

Market sentiment

Posts on X, past 7 days

An AI-synthesised read of the highest-engagement posts about System1 Biosciences on X, ranked by likes and reposts, corporate channels excluded.

Reading the room on X — pulling top posts and synthesizing themes…

Source: X recent search ranked by engagement (likes + retweets) · Synthesis by Claude · Cached for 1 hour

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