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Stipple Bio

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Precision oncology via the Pointillist Platform for tumor-specific epitopes

Cambridge, United StatesFounded 2022Biotech & Life Sciences
Valuation $1–2.5B Last recorded · 2026
Headcount <100 Current team size
Total funding $100–500M Disclosed equity funding
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About Stipple Bio

Stipple Bio is a Cambridge, Massachusetts biotechnology company that uses its Pointillist Platform to identify tumor-specific cell-surface epitopes and develop precision oncology medicines with a higher therapeutic index across modalities such as ADCs, T-cell engagers and radiopharmaceuticals. Founded by cancer biologists Dr Aaron Ring (Fred Hutch) and Dr Aashish Manglik (UCSF) and led by CEO Jeff Landau, Stipple’s lead candidate STP-100 is a novel ADC designed to avoid on-target/off-tumor toxicity and is expected to enter clinical studies in early 2027. In April 2026 Stipple emerged from stealth with an oversubscribed $100 million Series A co-led by RA Capital, a16z Bio+Health and Nextech Invest, with Emerson Collective Investments (Yosemite), GV, LoLa Capital Partners and GordonMD Global Investments, to advance STP-100 into early clinical studies and expand the pipeline. Sources: Stipple Bio 6 Apr 2026.

Source: Dealroom company data

At a glance

Status
Operational
Founded
2022
Headquarters
Cambridge, United States
Employees
13
Open positions
6
Dealroom signal
88.3/100
Industry
Health
Sub-industry
Pharmaceutical, BioTechnology
Sector
Biotech & Life Sciences, Biotechnology, Oncology, Precision Medicine, Spinout, Verified Unicorns and $1B Exits, AI Drug Discovery, Techbio, DT and LS, science-based
Client focus
b2b

Funding history

4 recorded events

Company financing events and reported valuations.

Deal typeDateAmountValuationInvestorsSource
SERIES AOther financing Apr 2026 $100M $2.2B GV · GordonMD Global Investment · Nextech Invest · a16z Bio + Health ↗
EARLY VCOther financing Dec 2024 $9.5M $38M Undisclosed ↗
Showing the latest 2 of 4 recorded eventsBook a demo for the full funding history →

Growth signals

Stipple Bio website traffic

Latest recorded traffic for Stipple Bio is 4.3K monthly website visits, up 53.6% over the last three months. Stipple Bio's team grew 116.7% over the past year.

Latest monthly visits4.3K 3-month web change+53.6% 1-year team growth+116.7%
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Similar companies

Closest operating peers by Dealroom taxonomy

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Investments and acquisitions

Capital deployed

Recent portfolio relationships for companies that also act as investors or acquirers.

Investors

8 investors on the cap table

From Dealroom's funding and investor records, grouped by the round each investor first entered.

Seed3 investors entered at this stage

Series A4 investors entered at this stage

Other known investors1 additional known investor

  • Yale University School of Medicine
Team profiled 4 named & role-tagged
Founders Hidden — book a demo/100 quality score
Key operators 3 quality Hidden — book a demo/100
Potential founders Hidden — book a demo likely future founders
Startup mafia Hidden — book a demo alumni-founded startups
Talent movements Hidden — book a demo in · Hidden — book a demo out past 12 months

Source: Dealroom Talent Intelligence.

Global footprint

Workforce and web traffic by country
Workforce by country
1 countries with
team presence
🇺🇸 United States100%
1 country shown

Market sentiment

Posts on X, past 7 days

An AI-synthesised read of the highest-engagement posts about Stipple Bio on X, ranked by likes and reposts, corporate channels excluded.

Reading the room on X — pulling top posts and synthesizing themes…

Source: X recent search ranked by engagement (likes + retweets) · Synthesis by Claude · Cached for 1 hour

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