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Stipple Bio
Precision oncology via the Pointillist Platform for tumor-specific epitopes
About Stipple Bio
Stipple Bio is a Cambridge, Massachusetts biotechnology company that uses its Pointillist Platform to identify tumor-specific cell-surface epitopes and develop precision oncology medicines with a higher therapeutic index across modalities such as ADCs, T-cell engagers and radiopharmaceuticals. Founded by cancer biologists Dr Aaron Ring (Fred Hutch) and Dr Aashish Manglik (UCSF) and led by CEO Jeff Landau, Stipple’s lead candidate STP-100 is a novel ADC designed to avoid on-target/off-tumor toxicity and is expected to enter clinical studies in early 2027. In April 2026 Stipple emerged from stealth with an oversubscribed $100 million Series A co-led by RA Capital, a16z Bio+Health and Nextech Invest, with Emerson Collective Investments (Yosemite), GV, LoLa Capital Partners and GordonMD Global Investments, to advance STP-100 into early clinical studies and expand the pipeline. Sources: Stipple Bio 6 Apr 2026.
Source: Dealroom company dataAt a glance
- Status
- Operational
- Founded
- 2022
- Headquarters
- Cambridge, United States
- Employees
- 13
- Open positions
- 6
- Dealroom signal
- 88.3/100
- Industry
- Health
- Sub-industry
- Pharmaceutical, BioTechnology
- Sector
- Biotech & Life Sciences, Biotechnology, Oncology, Precision Medicine, Spinout, Verified Unicorns and $1B Exits, AI Drug Discovery, Techbio, DT and LS, science-based
- Client focus
- b2b
Knowledge graph
More headlines
Funding history
Company financing events and reported valuations.
| Deal type | Date | Amount | Valuation | Investors | Source |
|---|---|---|---|---|---|
| SERIES AOther financing | Apr 2026 | $100M | $2.2B | GV · GordonMD Global Investment · Nextech Invest · a16z Bio + Health | ↗ |
| EARLY VCOther financing | Dec 2024 | $9.5M | $38M | Undisclosed | ↗ |
Growth signals
Latest recorded traffic for Stipple Bio is 4.3K monthly website visits, up 53.6% over the last three months. Stipple Bio's team grew 116.7% over the past year.
Open positions
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Investments and acquisitions
Recent portfolio relationships for companies that also act as investors or acquirers.
Investors
From Dealroom's funding and investor records, grouped by the round each investor first entered.
Seed3 investors entered at this stage
a16z Bio + Health
Emerson Collective
OMX Ventures
Series A4 investors entered at this stage
Nextech Invest
RA Capital Management
GV
GordonMD Global Investment
Other known investors1 additional known investor
Yale University School of Medicine
Source: Dealroom Talent Intelligence.
Global footprint
team presence
Market sentiment
An AI-synthesised read of the highest-engagement posts about Stipple Bio on X, ranked by likes and reposts, corporate channels excluded.
Reading the room on X — pulling top posts and synthesizing themes…
Source: X recent search ranked by engagement (likes + retweets) · Synthesis by Claude · Cached for 1 hour
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