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Pliant Therapeutics

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Discovering, developing and commercializing treatments for fibrotic diseases

South San Francisco, United StatesFounded 2016Biotech & Life Sciences
Valuation $51M Market cap · 2026

About Pliant Therapeutics

Pliant Therapeutics, accessible via pliantrx.com, is a pioneering biotech company focused on developing innovative treatments for fibrotic diseases. Fibrotic diseases involve the thickening and scarring of connective tissue, which can lead to organ dysfunction. Pliant's mission is to halt the progression of these diseases and ultimately reverse their effects, thereby restoring normal organ function.

The company operates in the biopharmaceutical market, targeting a range of fibrotic diseases. Their approach is rooted in deep scientific expertise, particularly in fibrosis (the formation of excess fibrous connective tissue), integrin biology (proteins that facilitate cell adhesion and signal transduction), medicinal chemistry, and advanced screening technology. By understanding the biological drivers of fibrosis, Pliant aims to create best-in-class treatments that can be applied to multiple or specific disease indications.

Pliant's business model revolves around drug development. They advance their pipeline of drug candidates through rigorous clinical trials, aiming to bring these novel therapeutics to market. Revenue is generated primarily through the successful development and commercialization of these drugs, either independently or through partnerships with larger pharmaceutical companies.

The company serves a diverse clientele, including patients suffering from fibrotic diseases, healthcare providers, and the broader medical research community. By focusing on the specific inhibition of integrins and related pathways in fibrotic tissues, Pliant aims to offer targeted and effective treatments.

In summary, Pliant Therapeutics is dedicated to transforming the treatment landscape for fibrotic diseases through cutting-edge science and innovative drug development.

Source: Dealroom company data

At a glance

Status
Listed
Founded
2016
Headquarters
South San Francisco, United States
Listing
IPO 2020
Sector
Biotech & Life Sciences

Investors

13 investors on the cap table

From Dealroom's funding and investor records, grouped by the round each investor first entered.

Series A7 investors entered at this stage

Series B and later6 investors entered at this stage

Team profiled 18 named & role-tagged
Founders Hidden — book a demo/100 quality score
Key operators 2 quality Hidden — book a demo/100
Potential founders Hidden — book a demo likely future founders
Startup mafia Hidden — book a demo alumni-founded startups
Talent movements Hidden — book a demo in · Hidden — book a demo out past 12 months

Source: Dealroom Talent Intelligence.

Global footprint

Workforce and web traffic by country
Workforce by country
🇺🇸 United States · South San Francisco HQ
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Market sentiment

Posts on X, past 7 days

An AI-synthesised read of the highest-engagement posts about Pliant Therapeutics on X, ranked by likes and reposts, corporate channels excluded.

Reading the room on X — pulling top posts and synthesizing themes…

Source: X recent search ranked by engagement (likes + retweets) · Synthesis by Claude · Cached for 1 hour

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