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Nucleome Therapeutics

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Decoding the dark matter of the human genome to discover first-in-class precision medicine

Oxford, United KingdomFounded 2019Biotech & Life Sciences
Valuation $100–250M Last recorded · 2022
Headcount <100 Current team size
Total funding $10–50M Disclosed equity funding
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About Nucleome Therapeutics

Nucleome Therapeutics is a cutting-edge biotech startup that focuses on unlocking the non-coding genome to improve human health. The company leverages advanced understanding of genetic variations to identify pathways affected by diseases and discover new drug targets, particularly for autoimmune diseases—a market valued at over $35 billion.

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Nucleome Therapeutics operates in the biotechnology and pharmaceutical sectors, serving clients such as pharmaceutical companies, research institutions, and healthcare providers. The company’s proprietary platform combines expertise in bioinformatics (the use of software and computational methods to understand biological data), genomics (the study of genomes), and the 3D structure of chromosomes. This platform is built on research from the University of Oxford and utilizes machine learning and 3D chromosomal analysis to link genetic variants to the gene targets they influence. This approach helps in identifying high-quality, low-risk drug targets across various diseases.

The business model of Nucleome Therapeutics revolves around the discovery and validation of new drug targets. The company makes money by partnering with pharmaceutical companies for drug development, licensing its technology, and potentially through drug repurposing (finding new uses for existing drugs). The company’s unique combination of computational and experimental methods allows it to validate targets at scale, making it a valuable partner in the drug discovery process.

Founded in 2019 as a spin-out from the University of Oxford, Nucleome Therapeutics has built its foundation on a decade of research and initial seed investment. The company aims to expand its applications to other cell types and explore new partnerships for further growth.

Source: Dealroom company data

At a glance

Status
Operational
Founded
2019
Headquarters
Oxford, United Kingdom
Employees
51
Open positions
4
Dealroom signal
65.8/100
Industry
Health
Sub-industry
Pharmaceutical, BioTechnology
Sector
Biotech & Life Sciences, Biotechnology, DNA, Genetics and genomics, Sequencing, Core AI
Technology
Artificial Intelligence, Hardware, 3D Technology, Deep Tech
Business model
Manufacturing
Client focus
b2b

Funding history

4 recorded events

Company financing events and reported valuations.

Deal typeDateAmountValuationInvestorsSource
SERIES A✓Equity / VC Oct 2022 $40M $160M Johnson & Johnson Innovation · Pfizer Ventures · Oxford Science Enterprises · M Ventures ↗
SUPPORT PROGRAM✓Other financing Jun 2020 $0 — Creative Destruction Lab ↗
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Growth signals

Nucleome Therapeutics website traffic

Latest recorded traffic for Nucleome Therapeutics is 1.6K monthly website visits, down 5.9% over the last three months. Nucleome Therapeutics's team declined 7.3% over the past year.

Latest monthly visits1.6K 3-month web change-5.9% 1-year team growth-7.3%
Summary metrics are public; monthly history is available with a demoCompare with peers →

Similar companies

Closest operating peers by Dealroom taxonomy

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Investments and acquisitions

Capital deployed

Recent portfolio relationships for companies that also act as investors or acquirers.

Investors

9 investors on the cap table

From Dealroom's funding and investor records, grouped by the round each investor first entered.

Series A5 investors entered at this stage

  • M Ventures
  • Johnson & Johnson Innovation
  • Pfizer Ventures
  • Oxford Science Enterprises
  • British Patient Capital

Other known investors4 additional known investors

  • Creative Destruction Lab
  • Oxford University Innovation
  • University of Oxford
  • OUI Startup Incubator
Team profiled 7 named & role-tagged
Founders Hidden — book a demo/100 quality score
Key operators 3 quality Hidden — book a demo/100
Potential founders Hidden — book a demo likely future founders
Startup mafia Hidden — book a demo alumni-founded startups
Talent movements Hidden — book a demo in · Hidden — book a demo out past 12 months

Source: Dealroom Talent Intelligence.

Global footprint

Workforce and web traffic by country
Workforce by country
4 countries with
team presence
🇬🇧 United Kingdom88.6%
🇳🇱 Netherlands6.8%
🇪🇸 Spain2.3%
🇺🇸 United States2.3%
4 countries shown

Market sentiment

Posts on X, past 7 days

An AI-synthesised read of the highest-engagement posts about Nucleome Therapeutics on X, ranked by likes and reposts, corporate channels excluded.

Reading the room on X — pulling top posts and synthesizing themes…

Source: X recent search ranked by engagement (likes + retweets) · Synthesis by Claude · Cached for 1 hour

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