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Nucleome Therapeutics
Decoding the dark matter of the human genome to discover first-in-class precision medicine
About Nucleome Therapeutics
Nucleome Therapeutics is a cutting-edge biotech startup that focuses on unlocking the non-coding genome to improve human health. The company leverages advanced understanding of genetic variations to identify pathways affected by diseases and discover new drug targets, particularly for autoimmune diseases—a market valued at over $35 billion.
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Nucleome Therapeutics operates in the biotechnology and pharmaceutical sectors, serving clients such as pharmaceutical companies, research institutions, and healthcare providers. The company’s proprietary platform combines expertise in bioinformatics (the use of software and computational methods to understand biological data), genomics (the study of genomes), and the 3D structure of chromosomes. This platform is built on research from the University of Oxford and utilizes machine learning and 3D chromosomal analysis to link genetic variants to the gene targets they influence. This approach helps in identifying high-quality, low-risk drug targets across various diseases.
The business model of Nucleome Therapeutics revolves around the discovery and validation of new drug targets. The company makes money by partnering with pharmaceutical companies for drug development, licensing its technology, and potentially through drug repurposing (finding new uses for existing drugs). The company’s unique combination of computational and experimental methods allows it to validate targets at scale, making it a valuable partner in the drug discovery process.
Founded in 2019 as a spin-out from the University of Oxford, Nucleome Therapeutics has built its foundation on a decade of research and initial seed investment. The company aims to expand its applications to other cell types and explore new partnerships for further growth.
At a glance
- Status
- Operational
- Founded
- 2019
- Headquarters
- Oxford, United Kingdom
- Employees
- 51
- Open positions
- 4
- Dealroom signal
- 65.8/100
- Industry
- Health
- Sub-industry
- Pharmaceutical, BioTechnology
- Sector
- Biotech & Life Sciences, Biotechnology, DNA, Genetics and genomics, Sequencing, Core AI
- Technology
- Artificial Intelligence, Hardware, 3D Technology, Deep Tech
- Business model
- Manufacturing
- Client focus
- b2b
Knowledge graph
More headlines
Funding history
Company financing events and reported valuations.
| Deal type | Date | Amount | Valuation | Investors | Source |
|---|---|---|---|---|---|
| SERIES A✓Equity / VC | Oct 2022 | $40M | $160M | Johnson & Johnson Innovation · Pfizer Ventures · Oxford Science Enterprises · M Ventures | ↗ |
| SUPPORT PROGRAM✓Other financing | Jun 2020 | $0 | — | Creative Destruction Lab | ↗ |
Growth signals
Latest recorded traffic for Nucleome Therapeutics is 1.6K monthly website visits, down 5.9% over the last three months. Nucleome Therapeutics's team declined 7.3% over the past year.
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Investments and acquisitions
Recent portfolio relationships for companies that also act as investors or acquirers.
Investors
From Dealroom's funding and investor records, grouped by the round each investor first entered.
Series A5 investors entered at this stage
M Ventures
Johnson & Johnson Innovation- PVPfizer Ventures
Oxford Science Enterprises
British Patient Capital
Other known investors4 additional known investors
Creative Destruction Lab
Oxford University Innovation
University of Oxford
OUI Startup Incubator
Source: Dealroom Talent Intelligence.
Global footprint
team presence
Market sentiment
An AI-synthesised read of the highest-engagement posts about Nucleome Therapeutics on X, ranked by likes and reposts, corporate channels excluded.
Reading the room on X — pulling top posts and synthesizing themes…
Source: X recent search ranked by engagement (likes + retweets) · Synthesis by Claude · Cached for 1 hour
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