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NodThera

Biotech & Life Sciences · Montrose, United Kingdom · Founded 2016

Small molecule drug candidate to treat inflammatory diseases, as well as other drugs for neurodegenerative diseases and cancers MoreLess

NodThera is a biotechnology company focused on developing innovative therapeutics targeting the NLRP3 inflammasome, a protein complex involved in the body's inflammatory response. The company operates in the pharmaceutical and healthcare market, serving patients suffering from chronic inflammatory diseases. NodThera's business model revolves around its proprietary drug discovery platform, which leverages advanced medicinal chemistry to create next-generation small molecule inhibitors. These inhibitors are designed for high potency, optimal pharmacokinetics (how the drug moves through the body), and effective tissue penetration. The company generates revenue through the development and potential commercialization of its drug candidates, as well as through partnerships and collaborations with other pharmaceutical companies. NodThera's lead candidate, NT 0167, is currently in Phase 1 clinical trials, assessing its safety and efficacy. The company is also progressing a pipeline of other NLRP3 inhibitors, including those capable of crossing the blood-brain barrier to treat neurological conditions.

Keywords: NLRP3 inflammasome, chronic diseases, drug discovery, small molecules, biotechnology, pharmacokinetics, Phase 1 clinical trial, medicinal chemistry, inflammation, neurological conditions.

Company overview

NodThera company information

The essential company record, classifications and operating signals in one place.

Status
Operational
Founded
2016
Headquarters
Montrose, United Kingdom
Employees
23
Open positions
1
Dealroom signal
69.5
client focusb2bsub industryBioTechnologybusiness modelManufacturingindustryHealthsectorBiotechnologysectorNeurologysectorBiotech and PharmasectorHard TechsectorproteomicssectorDT and LSsectoruk is8 life sciencessectorscience-based

Valuation & funding

NodThera funding history

Company financing events and reported valuations.

Deal typeDateAmountValuationInvestorsSource
SERIES BOther financing Oct 2021 $0 Undisclosed
SERIES BOther financing Jun 2020 $59M $165M Cowen Group · Epidarex Capital · F-Prime · Sanofi Ventures
SERIES AOther financing Jun 2018 $35M $141M Sofinnova Partners · Epidarex Capital · F-Prime · 5AM Ventures
EARLY VCOther financing Dec 2017 $475K $1.9M Undisclosed
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Financials

Revenue, earnings and profit over time

Reported history and available estimates. Estimated years are marked “E”; sparse fields are left blank rather than inferred.

YearEBITDAMargin
2026 −$24M
2025 −$24M
2024 −$24M
2023 −$24M
2022 −$24M
2021 −$28M
2020 −$22M
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Growth signals

NodThera website traffic

Latest recorded traffic for NodThera is 3.7K monthly website visits, up 306.6% over the last three months. NodThera's team grew 4.5% over the past year.

Latest monthly visits3.7K 3-month web change+306.6% 1-year team growth+4.5%
Monthly website visits106 observations · Jun 2017–Jul 2026
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Comparisons

NodThera compared with similar companies

Dealroom’s weighted taxonomy model identifies the closest operating peers. Company identity and context stay open; selected comparison metrics preview what is available in the platform.

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Talent graph

NodThera's talent

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Team profiled 11 named & role-tagged
Founders Hidden — book a demo/100 quality score
Key operators 5 quality Hidden — book a demo/100
Potential founders Hidden — book a demo likely future founders
Startup mafia Hidden — book a demo alumni-founded startups
Talent movements Hidden — book a demo in · Hidden — book a demo out past 12 months

Source: Dealroom Talent Intelligence.

Investors

7 investors on NodThera's cap table

Sourced from Dealroom's funding and investor records. Investor profile links are shown where available.

Series A 7 investors entered at this stage
5AM Ventures
Sofinnova Partners
Epidarex Capital
F-Prime
Cowen Group
Sanofi Ventures
Novo Ventures

Global footprint

Where NodThera has talent and traffic

Workforce by country
🇬🇧 United Kingdom · Montrose HQ
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In the news

Latest news about NodThera

Recent press, funding announcements, and product moves mentioning NodThera — open to read from the original sources.

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Market sentiment

What the market is saying about NodThera

An AI-synthesized read of the highest-engagement posts about NodThera on X over the past 7 days. We rank by likes & retweets, ignore corporate channels, and surface the themes that broke out from real people.

Reading the room on X — pulling top posts and synthesizing themes…

Source: X recent search ranked by engagement (likes + retweets) · Synthesis by Claude · Cached for 1 hour

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