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Gate Neurosciences

Biotech & Life Sciences · Indianapolis, United States · Founded 2019

A healthcare company that offers neuroscience-related medical services MoreLess

Gate Neurosciences is a biotech startup that focuses on developing innovative treatments for central nervous system (CNS) diseases. The company's mission is to provide a new generation of safe, potent, and rapid-acting therapies for the nearly 1 billion people globally who suffer from neuropsychiatric and cognitive disorders.

Gate Neurosciences operates in the biotech and healthcare market, serving patients with CNS disorders, including depression. The company's business model revolves around the development and commercialization of novel therapies that enhance synaptic function, which is the biological basis for many CNS disorders.

The company's primary revenue stream is expected to come from the sale of its therapeutic candidates once they have been approved for use. Their lead program, zelquistinel, is an oral NMDAR PAM (a type of drug that enhances the function of the NMDA receptor in the brain) that has shown promising results in a Phase 2a study for Major Depressive Disorder. The next Phase 2 study is set to be initiated in 2023.

The team at Gate Neurosciences, led by President and CEO Michael G. McCully, has decades of experience in researching CNS disease biology and improving the treatment of CNS disorders. This deep expertise positions the company well for meaningful innovation in the field.

Keywords: Biotech, Healthcare, Central Nervous System, Neuropsychiatric Disorders, Cognitive Disorders, Synaptic Function, Therapeutic Candidates, NMDAR PAM, Major Depressive Disorder, Clinical Trials.

Company overview

Gate Neurosciences company information

The essential company record, classifications and operating signals in one place.

Status
Acquired
Founded
2019
Headquarters
Indianapolis, United States
Employees
1
Open positions
None listed
Dealroom signal
58.8
client focusb2bsub industryPharmaceuticalsub industryBioTechnologybusiness modelManufacturingindustryHealthsectorBiotechnologysectorBiotech and PharmasectorHard TechsectorDT and LSsectorscience-based

Valuation & funding

Gate Neurosciences funding history

Company financing events and reported valuations.

Deal typeDateAmountValuationInvestorsSource
ACQUISITIONExit May 2025 $0 Syndeio Biosciences
EARLY VCEquity / VC Oct 2022 $25M $100M Thornapple River Capital · BioCrossroads · Innoviva
DEBTDebt Dec 2021 $15M Undisclosed
DEBTDebt Jul 2020 $1.1M Undisclosed
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Financials

Workforce over time

Available workforce history. Financial fields without reported data are omitted.

YearEmployees
2026 1
2025 3
2024 15
2023 8
2022 8
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Growth signals

Gate Neurosciences website traffic

Latest recorded traffic for Gate Neurosciences is 130 monthly website visits, down 93.8% over the last three months. Gate Neurosciences's team declined 66.7% over the past year.

Latest monthly visits130 3-month web change-93.8% 1-year team growth-66.7%
Monthly website visits26 observations · Oct 2022–Aug 2025
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Comparisons

Gate Neurosciences compared with similar companies

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Showing 8 of the closest matchesCompare every metric →

Talent graph

Gate Neurosciences's talent

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Team profiled 3 named & role-tagged
Founders Hidden — book a demo/100 quality score
Key operators 3 quality Hidden — book a demo/100
Potential founders Hidden — book a demo likely future founders
Startup mafia Hidden — book a demo alumni-founded startups
Talent movements Hidden — book a demo in · Hidden — book a demo out past 12 months

Source: Dealroom Talent Intelligence.

Investors

4 investors on Gate Neurosciences's cap table

Sourced from Dealroom's funding and investor records.

Series A 3 investors entered at this stage
Thornapple River Capital
BioCrossroads
Innoviva
Other known 1 additional known investor
Syndeio Biosciences

Global footprint

Where Gate Neurosciences has talent and traffic

Workforce by country
1 countries with
team presence
🇺🇸 United States100%
1 country shown

In the news

Latest news about Gate Neurosciences

Recent press, funding announcements, and product moves mentioning Gate Neurosciences — open to read from the original sources.

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Market sentiment

What the market is saying about Gate Neurosciences

An AI-synthesized read of the highest-engagement posts about Gate Neurosciences on X over the past 7 days. We rank by likes & retweets, ignore corporate channels, and surface the themes that broke out from real people.

Reading the room on X — pulling top posts and synthesizing themes…

Source: X recent search ranked by engagement (likes + retweets) · Synthesis by Claude · Cached for 1 hour

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