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Gate Neurosciences
Biotech & Life Sciences · Indianapolis, United States · Founded 2019
A healthcare company that offers neuroscience-related medical services MoreLess
Gate Neurosciences is a biotech startup that focuses on developing innovative treatments for central nervous system (CNS) diseases. The company's mission is to provide a new generation of safe, potent, and rapid-acting therapies for the nearly 1 billion people globally who suffer from neuropsychiatric and cognitive disorders.
Gate Neurosciences operates in the biotech and healthcare market, serving patients with CNS disorders, including depression. The company's business model revolves around the development and commercialization of novel therapies that enhance synaptic function, which is the biological basis for many CNS disorders.
The company's primary revenue stream is expected to come from the sale of its therapeutic candidates once they have been approved for use. Their lead program, zelquistinel, is an oral NMDAR PAM (a type of drug that enhances the function of the NMDA receptor in the brain) that has shown promising results in a Phase 2a study for Major Depressive Disorder. The next Phase 2 study is set to be initiated in 2023.
The team at Gate Neurosciences, led by President and CEO Michael G. McCully, has decades of experience in researching CNS disease biology and improving the treatment of CNS disorders. This deep expertise positions the company well for meaningful innovation in the field.
Keywords: Biotech, Healthcare, Central Nervous System, Neuropsychiatric Disorders, Cognitive Disorders, Synaptic Function, Therapeutic Candidates, NMDAR PAM, Major Depressive Disorder, Clinical Trials.
Company overview
Gate Neurosciences company information
The essential company record, classifications and operating signals in one place.
- Status
- Acquired
- Founded
- 2019
- Headquarters
- Indianapolis, United States
- Employees
- 1
- Open positions
- None listed
- Dealroom signal
- 58.8
Valuation & funding
Gate Neurosciences funding history
Company financing events and reported valuations.
| Deal type | Date | Amount | Valuation | Investors | Source |
|---|---|---|---|---|---|
| ACQUISITION✓Exit | May 2025 | $0 | — | Syndeio Biosciences | — |
| EARLY VC✓Equity / VC | Oct 2022 | $25M | $100M | Thornapple River Capital · BioCrossroads · Innoviva | ↗ |
| DEBT✓Debt | Dec 2021 | $15M | — | Undisclosed | — |
| DEBT✓Debt | Jul 2020 | $1.1M | — | Undisclosed | — |
Financials
Workforce over time
Available workforce history. Financial fields without reported data are omitted.
| Year | Employees |
|---|---|
| 2026 | 1 |
| 2025 | 3 |
| 2024 | 15 |
| 2023 | 8 |
| 2022 | 8 |
Growth signals
Gate Neurosciences website traffic
Latest recorded traffic for Gate Neurosciences is 130 monthly website visits, down 93.8% over the last three months. Gate Neurosciences's team declined 66.7% over the past year.
Comparisons
Gate Neurosciences compared with similar companies
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Talent graph
Gate Neurosciences's talent
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Investors
4 investors on Gate Neurosciences's cap table
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Global footprint
Where Gate Neurosciences has talent and traffic
team presence
In the news
Latest news about Gate Neurosciences
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Market sentiment
What the market is saying about Gate Neurosciences
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