E
Entact Bio
A preclinical stage biotechnology company developing a new class of drugs that enhance the function of beneficial proteins
About Entact Bio
Entact Bio is a biotechnology startup that operates in the pharmaceutical industry, focusing on the development of innovative drugs that enhance protein function to treat a wide range of diseases. The company's unique approach is to enhance proteins that can restore health, rather than inhibiting proteins that contribute to disease. This is achieved by extending the lifespan of key proteins, relocating misplaced proteins within cells, and altering protein structures or interactions.
Read full description
Entact Bio's primary product is ENTAC™ medicines, which are designed to target previously undruggable pathways, address difficult-to-treat genetic disorders, and treat common complex diseases. ENTACs work by acting as molecular matchmakers, pairing target proteins with enzymes called DUBs (Deubiquitinases) to enhance protein function. This innovative approach could potentially revolutionize the treatment of various diseases.
The company's business model revolves around the development and optimization of these ENTACs through their proprietary Encompass™ platform. This platform provides an end-to-end system for efficiently creating ENTACs, from identifying suitable targets to validating the ENTAC-disease hypothesis and designing target-specific ENTACs.
Entact Bio's revenue generation strategy is likely based on the commercialization of their ENTAC medicines, either through direct sales or licensing agreements with larger pharmaceutical companies. The company serves a broad market, including patients suffering from genetic disorders and complex diseases.
The team behind Entact Bio is composed of scientists, entrepreneurs, drug creators, and problem solvers, led by executives with a track record of transforming ideas into medicines. The company is backed by investors who are willing to push the boundaries of drug development.
At a glance
- Status
- Operational
- Founded
- 2019
- Headquarters
- Watertown, United States
- Employees
- 24
- Open positions
- None listed
- Dealroom signal
- 62.2/100
- Industry
- Health
- Sub-industry
- BioTechnology
- Sector
- Biotech & Life Sciences, Biotechnology, Spinout, Biotech and Pharma, Longevity, proteomics, DT and LS, science-based
- Business model
- Manufacturing
- Client focus
- b2b
Latest news
Press, funding announcements and product moves mentioning Entact Bio.
Funding history
Company financing events and reported valuations.
| Deal type | Date | Amount | Valuation | Investors | Source |
|---|---|---|---|---|---|
| SERIES AOther financing | Jan 2024 | $40M | $405M | Undisclosed | ↗ |
| SERIES AOther financing | Dec 2022 | $81M | $324M | Abingworth · Arkin Capital · Brandon Capital Partners · Janus Henderson Investors | ↗ |
Growth signals
Latest recorded traffic for Entact Bio is 710 monthly website visits, down 62.6% over the last three months. Entact Bio's team declined 27.3% over the past year.
Similar companies
Company identity and context are open; selected comparison metrics preview what is available on the platform.
Investors
From Dealroom's funding and investor records, grouped by the round each investor first entered.
Series A10 investors entered at this stage
Abingworth
Arkin Capital
Brandon Capital PartnersJanus Henderson Investors
Logos Capital
WEHI
Surveyor Capital
venBio Partners
Qiming Venture Partners
4BIO Capital
Other known investors1 additional known investor
Harvard University
Source: Dealroom Talent Intelligence.
Global footprint
team presence
Market sentiment
An AI-synthesised read of the highest-engagement posts about Entact Bio on X, ranked by likes and reposts, corporate channels excluded.
Reading the room on X — pulling top posts and synthesizing themes…
Source: X recent search ranked by engagement (likes + retweets) · Synthesis by Claude · Cached for 1 hour
See Entact Bio’s full profile on Dealroom
Request a free trial to see the complete deal history, financials, people graph and growth signals.
Takes under a minute. Already use Dealroom? Log in.







