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Entact Bio

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A preclinical stage biotechnology company developing a new class of drugs that enhance the function of beneficial proteins

Watertown, United StatesFounded 2019Biotech & Life Sciences
Valuation $100–500M Latest valuation · 2024
Headcount <100 Current team size
Total funding $100–500M Disclosed equity funding
Unlock exact values This page shows ranges. Dealroom has the exact numbers for Entact Bio and the history behind them.

About Entact Bio

Entact Bio is a biotechnology startup that operates in the pharmaceutical industry, focusing on the development of innovative drugs that enhance protein function to treat a wide range of diseases. The company's unique approach is to enhance proteins that can restore health, rather than inhibiting proteins that contribute to disease. This is achieved by extending the lifespan of key proteins, relocating misplaced proteins within cells, and altering protein structures or interactions.

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Entact Bio's primary product is ENTAC™ medicines, which are designed to target previously undruggable pathways, address difficult-to-treat genetic disorders, and treat common complex diseases. ENTACs work by acting as molecular matchmakers, pairing target proteins with enzymes called DUBs (Deubiquitinases) to enhance protein function. This innovative approach could potentially revolutionize the treatment of various diseases.

The company's business model revolves around the development and optimization of these ENTACs through their proprietary Encompass™ platform. This platform provides an end-to-end system for efficiently creating ENTACs, from identifying suitable targets to validating the ENTAC-disease hypothesis and designing target-specific ENTACs.

Entact Bio's revenue generation strategy is likely based on the commercialization of their ENTAC medicines, either through direct sales or licensing agreements with larger pharmaceutical companies. The company serves a broad market, including patients suffering from genetic disorders and complex diseases.

The team behind Entact Bio is composed of scientists, entrepreneurs, drug creators, and problem solvers, led by executives with a track record of transforming ideas into medicines. The company is backed by investors who are willing to push the boundaries of drug development.

Source: Dealroom company data

At a glance

Status
Operational
Founded
2019
Headquarters
Watertown, United States
Employees
24
Open positions
None listed
Dealroom signal
62.2/100
Industry
Health
Sub-industry
BioTechnology
Sector
Biotech & Life Sciences, Biotechnology, Spinout, Biotech and Pharma, Longevity, proteomics, DT and LS, science-based
Business model
Manufacturing
Client focus
b2b

Latest news

Press, funding announcements and product moves mentioning Entact Bio.

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Funding history

3 recorded events

Company financing events and reported valuations.

Deal typeDateAmountValuationInvestorsSource
SERIES AOther financing Jan 2024 $40M $405M Undisclosed
SERIES AOther financing Dec 2022 $81M $324M Abingworth · Arkin Capital · Brandon Capital Partners · Janus Henderson Investors
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Growth signals

Entact Bio website traffic

Latest recorded traffic for Entact Bio is 710 monthly website visits, down 62.6% over the last three months. Entact Bio's team declined 27.3% over the past year.

Latest monthly visits710 3-month web change-62.6% 1-year team growth-27.3%
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Similar companies

Closest operating peers by Dealroom taxonomy

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Investors

11 investors on the cap table

From Dealroom's funding and investor records, grouped by the round each investor first entered.

Series A10 investors entered at this stage

Other known investors1 additional known investor

  • Harvard University
Team profiled 8 named & role-tagged
Founders Hidden — book a demo/100 quality score
Key operators 1 quality Hidden — book a demo/100
Potential founders Hidden — book a demo likely future founders
Startup mafia Hidden — book a demo alumni-founded startups
Talent movements Hidden — book a demo in · Hidden — book a demo out past 12 months

Source: Dealroom Talent Intelligence.

Global footprint

Workforce and web traffic by country
Workforce by country
2 countries with
team presence
🇺🇸 United States95.8%
🇦🇺 Australia4.2%
2 countries shown

Market sentiment

Posts on X, past 7 days

An AI-synthesised read of the highest-engagement posts about Entact Bio on X, ranked by likes and reposts, corporate channels excluded.

Reading the room on X — pulling top posts and synthesizing themes…

Source: X recent search ranked by engagement (likes + retweets) · Synthesis by Claude · Cached for 1 hour

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