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Casma Therapeutics

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Harnessing the natural cellular process of autophagy to design powerful new medicines for a broad range of diseases

Cambridge, United StatesFounded 2018Biotech & Life Sciences
Valuation $250–500M Last recorded · 2022
Headcount <100 Current team size
Total funding $100–500M Disclosed equity funding
Unlock exact values This page shows ranges. Dealroom has the exact numbers for Casma Therapeutics and the history behind them.

About Casma Therapeutics

Casma Therapeutics is a biotechnology startup that operates in the healthcare sector, specifically in the field of disease treatment. The company's primary focus is on reprogramming autophagy, a natural process in the body that removes damaged components within cells to maintain and improve health. Casma's innovative approach involves enhancing this process to treat diseases that current drugs have been unable to effectively target.

The company's business model revolves around its proprietary PHLYT™ (Phagosome-Lysosome Targeting) platform. This platform initiates target-specific autophagic degradation of new disease targets, regardless of their size or complexity. In simpler terms, it enhances the body's natural process of removing damaged components in cells to treat diseases.

Casma Therapeutics serves a broad range of clients, including patients suffering from diseases that are currently difficult to treat with existing drugs. The company generates revenue through the development and commercialization of its PHLYT™ platform and related treatments.

Recently, the company has made significant strides in its operations, raising $46.0 million in Series C funding and presenting at the Stifel 2022 Healthcare Conference. These developments indicate a positive trajectory for the company's growth and its potential to make a significant impact in the healthcare sector.

Source: Dealroom company data

At a glance

Status
Operational
Founded
2018
Headquarters
Cambridge, United States
Employees
11
Open positions
None listed
Dealroom signal
40.9/100
Industry
Health
Sub-industry
BioTechnology
Sector
Biotech & Life Sciences, Biotechnology, Biotech and Pharma, Hard Tech, DT and LS, science-based
Business model
Manufacturing
Client focus
b2b

Funding history

5 recorded events

Company financing events and reported valuations.

Deal typeDateAmountValuationInvestorsSource
GRANTOther financing Mar 2026 $7.6M — Michael J. Fox Foundation for Parkinson's Research ↗
SERIES COther financing Nov 2022 $46M $293M Third Rock Ventures · The Column Group · Astellas Venture · Ono Venture Investment ↗
Showing the latest 2 of 5 recorded eventsBook a demo for the full funding history →

Growth signals

Casma Therapeutics website traffic

Latest recorded traffic for Casma Therapeutics is 2K monthly website visits, down 9.1% over the last three months. Casma Therapeutics's team grew 0% over the past year.

Latest monthly visits2K 3-month web change-9.1% 1-year team growth0%
Summary metrics are public; monthly history is available with a demoCompare with peers →

Similar companies

Closest operating peers by Dealroom taxonomy

Company identity and context are open; selected comparison metrics preview what is available on the platform.

Showing 8 of the closest matchesCompare every metric →

Investments and acquisitions

Capital deployed

Recent portfolio relationships for companies that also act as investors or acquirers.

Investors

12 investors on the cap table

From Dealroom's funding and investor records, grouped by the round each investor first entered.

Seed1 investor entered at this stage

  • Michael J. Fox Foundation for Parkinson's Research

Series A4 investors entered at this stage

Series B and later7 investors entered at this stage

  • Astellas Venture
  • Ono Venture Investment
  • Mirae Asset Venture Investment
  • Eisai
  • Amgen Ventures
  • Euclidean Capital
  • Schroders Capital
Team profiled 7 named & role-tagged
Founders Hidden — book a demo/100 quality score
Key operators 2 quality Hidden — book a demo/100
Potential founders Hidden — book a demo likely future founders
Startup mafia Hidden — book a demo alumni-founded startups
Talent movements Hidden — book a demo in · Hidden — book a demo out past 12 months

Source: Dealroom Talent Intelligence.

Global footprint

Workforce and web traffic by country
Workforce by country
1 countries with
team presence
🇺🇸 United States100%
1 country shown

Market sentiment

Posts on X, past 7 days

An AI-synthesised read of the highest-engagement posts about Casma Therapeutics on X, ranked by likes and reposts, corporate channels excluded.

Reading the room on X — pulling top posts and synthesizing themes…

Source: X recent search ranked by engagement (likes + retweets) · Synthesis by Claude · Cached for 1 hour

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