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Avalo Therapeutics
Clinical-stage biotechnology company developing IL-1beta-targeted therapies for immune-mediated inflammatory diseases
About Avalo Therapeutics
Avalo Therapeutics is a clinical-stage biotechnology company developing therapeutics targeting the IL-1beta (interleukin-1 beta) pathway for immune-mediated inflammatory diseases.The company's lead candidate, abdakibart (AVTX-009), is a humanized monoclonal antibody designed to inhibit IL-1betaand block downstream inflammatory signaling; it is being advanced toward a registrational Phase 3 program following positive Phase 2 results in moderate-to-severe hidradenitis suppurativa,a chronic inflammatory skin condition. Avalo is also developing AVTX-010,a long-acting next-generation anti-IL-1beta monoclonal antibody intended to extend dosing intervals.
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The company is based in the United Statesand listed on the Nasdaq under the ticker AVTX.Formed from Cerecor,which changed its name to Avalo Therapeutics in 2021 following its mergerwith Aevi Genomic Medicine,the company shifted away from its earlier neuroscience focus toward immunologyand inflammation.Avalo's business model centers on research and development of novel biologic drug candidates,with eventual commercialization expected through pharmaceutical partnershipsand product sales.
At a glance
- Status
- Listed
- Founded
- 2011
- Headquarters
- Rockville, United States
- Listing
- IPO 2015
- Employees
- 48
- Open positions
- None listed
- Dealroom signal
- 91.3/100
- Industry
- Health
- Sub-industry
- Pharmaceutical, BioTechnology
- Sector
- Biotech & Life Sciences, Testing, Biotechnology, Neurology, Spinout, Biotech and Pharma, medical testing, DT and LS, science-based
- Business model
- Manufacturing
- Client focus
- b2b, b2c
- Investment activity
- 2 companies, latest Mar 2024
- Capital deployed
- —
- Preferred round
- ACQUISITION
Knowledge graph
More headlines
Funding history
Company financing events and reported valuations.
| Deal type | Date | Amount | Valuation | Investors | Source |
|---|---|---|---|---|---|
| POST IPO EQUITYOther financing | May 2026 | $375M | — | Undisclosed | ↗ |
| POST IPO EQUITYOther financing | Jun 2025 | $75M | — | Undisclosed | ↗ |
Financials
Revenue, earnings and other financial measures where available. Years marked “E” are estimates.
| Year | Revenue | Growth | EBITDA | Margin |
|---|---|---|---|---|
| 2026 | $59K | 0% | −$93M | -158118.6% |
| 2025 | $59K | -86.6% | −$10M | -16949.2% |
| 2024 | $441K | -77.1% | −$10M | -2267.6% |
| 2023 | $1.9M | -89.3% | −$10M | -519.8% |
| 2022 | $18M | +260% | −$10M | -55.6% |
| 2021 | $5M | -28.6% | −$10M | -200% |
| 2020 | $7M | — | −$10M | -142.9% |
Growth signals
Latest recorded traffic for Avalo Therapeutics is 2.9K monthly website visits, down 54.7% over the last three months. Avalo Therapeutics's team grew 2.1% over the past year.
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Investments and acquisitions
Recent portfolio relationships for companies that also act as investors or acquirers.
Investors
From Dealroom's funding and investor records, grouped by the round each investor first entered.
Seed1 investor entered at this stage
National Institute on Drug Abuse (NIDA)
Series A3 investors entered at this stage
MPM BioImpact
Apple Tree Partners
NEA
Series B and later1 investor entered at this stage
Horizon Technology Finance Corporation
Other known investors8 additional known investors
BVF Partners
Commodore Capital
Deep Track Capital
Johns Hopkins University
OrbiMed- PEPetrichor
RA Capital Management
TCGX
Source: Dealroom Talent Intelligence.
Global footprint
Market sentiment
An AI-synthesised read of the highest-engagement posts about Avalo Therapeutics on X, ranked by likes and reposts, corporate channels excluded.
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Source: X recent search ranked by engagement (likes + retweets) · Synthesis by Claude · Cached for 1 hour
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