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Aprea Therapeutics

Biotech & Life Sciences · Doylestown, United States · Founded 2003 · IPO 2019

Development of novel anticancer compounds MoreLess

Aprea Therapeutics is a cutting-edge biotechnology company focused on developing innovative cancer therapies. The company aims to become the global leader in p53-targeted cancer treatments. The p53 protein is crucial for regulating cell growth and preventing cancer; however, mutations in the p53 gene are common in many cancers, making it a prime target for therapeutic intervention.

Aprea's primary business involves pioneering the development of therapeutics designed to reactivate the p53 function. By restoring the normal function of this protein, Aprea aims to offer new treatment options for cancers that currently have limited or no effective therapies. Their pipeline includes investigational products that are undergoing clinical trials for various cancer indications, such as Myelodysplastic Syndromes (MDS) and Acute Myeloid Leukemia (AML).

The company serves a diverse range of clients, including healthcare providers, cancer treatment centers, and pharmaceutical companies. It operates in the highly specialized and competitive market of oncology therapeutics. Aprea's business model is based on extensive research and development (R&D), followed by clinical trials to validate the efficacy and safety of their products. Once approved, these products are commercialized and sold to healthcare providers and institutions.

Aprea makes money primarily through the sale of its therapeutic products once they receive regulatory approval. Additionally, the company may enter into partnerships or licensing agreements with other pharmaceutical firms, which can provide additional revenue streams through upfront payments, milestone payments, and royalties.

In summary, Aprea Therapeutics is at the forefront of cancer treatment innovation, focusing on reactivating the p53 protein to offer new hope for patients with difficult-to-treat cancers.

Keywords: biotechnology, cancer therapy, p53 protein, oncology, clinical trials, therapeutics, MDS, AML, R&D, pharmaceutical.

Revenue $409K
Total funding $100–500M

Talent graph

Aprea Therapeutics's talent

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Team profiled 9 named & role-tagged
Founders Hidden — book a demo/100 quality score
Key operators 6 quality Hidden — book a demo/100
Potential founders Hidden — book a demo likely future founders
Startup mafia Hidden — book a demo alumni-founded startups
Talent movements Hidden — book a demo in · Hidden — book a demo out past 12 months

Source: Dealroom Talent Intelligence.

Investors

13 investors on Aprea Therapeutics's cap table

Sourced from Dealroom's funding and investor records. Investor profile links are shown where available.

Series A 4 investors entered at this stage
5AM Ventures
Versant Ventures
Sectoral Asset Management
HealthCap
Series B+ 9 investors entered at this stage
Redmile Group
Karolinska Development
Rock Springs Capital
Janus Henderson Investors
Dafna Capital Management
Sphera Funds Management
Exome Asset Management
Nantahala Capital Management
Stonepine Capital Management

Global footprint

Where Aprea Therapeutics has talent and traffic

Workforce by country
2 countries with
team presence
🇺🇸 United States88.9%
🇸🇪 Sweden11.1%
2 countries shown

Market sentiment

What the market is saying about Aprea Therapeutics

An AI-synthesized read of the highest-engagement posts about Aprea Therapeutics on X over the past 7 days. We rank by likes & retweets, ignore corporate channels, and surface the themes that broke out from real people.

Reading the room on X — pulling top posts and synthesizing themes…

Source: X recent search ranked by engagement (likes + retweets) · Synthesis by Claude · Cached for 1 hour

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