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Annexon Biosciences
Biotech company, discovering and developing novel therapeutics for neurodegenerative and autoimmune disorders
About Annexon Biosciences
Annexon Biosciences is a clinical-stage biopharmaceutical company focused on developing innovative therapies for autoimmune and neurodegenerative diseases, including eye-related conditions. The company operates in the biopharmaceutical market, targeting diseases such as Alzheimer's, Huntington's, and glaucoma.
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Annexon's unique approach centers on the classical complement pathway, a part of the immune system that, when improperly activated, can lead to tissue damage. Their primary focus is on inhibiting C1q, the molecule that initiates this pathway. By blocking C1q, Annexon aims to prevent the cascade of events that cause disease progression, effectively "stopping the start" of these conditions.
The company's business model involves extensive research and development (R&D) to create these novel therapies. They conduct clinical trials to test the safety and effectiveness of their treatments. Once a therapy proves successful, Annexon can either bring it to market themselves or partner with larger pharmaceutical companies to distribute it. This model allows them to generate revenue through product sales, licensing agreements, and milestone payments from partners.
Annexon's clients primarily include patients suffering from autoimmune and neurodegenerative diseases, healthcare providers, and larger pharmaceutical companies looking for innovative treatments to add to their portfolios. The company recently secured $100 million in financing to advance its pipeline of therapies, highlighting strong investor confidence in their approach and potential.
In summary, Annexon Biosciences is at the forefront of developing first-in-class therapies targeting the classical complement pathway to treat a range of serious diseases. Their innovative approach and strong financial backing position them well in the competitive biopharmaceutical market.
At a glance
- Status
- Operational
- Founded
- 2011
- Headquarters
- San Francisco, United States
- Listing
- IPO 2020
- Employees
- 116
- Open positions
- 4
- Dealroom signal
- 34.4/100
- Industry
- Health
- Sub-industry
- Pharmaceutical, BioTechnology
- Sector
- Biotech & Life Sciences, Biotechnology, Ophthalmology, Neurology, Autoimmune, Eye Diseases, Degenerative Diseases, Health Diagnostics, Spinout, Biotech and Pharma
- Business model
- Manufacturing
- Client focus
- b2b
Knowledge graph
More headlines
Funding history
Company financing events and reported valuations.
| Deal type | Date | Amount | Valuation | Investors | Source |
|---|---|---|---|---|---|
| POST IPO EQUITYOther financing | Nov 2025 | $75M | — | Undisclosed | ↗ |
| POST IPO EQUITYOther financing | Jun 2024 | $125M | — | Undisclosed | ↗ |
Financials
Revenue, earnings and other financial measures where available. Years marked “E” are estimates.
| Year | Revenue | Growth | EBITDA | Margin |
|---|---|---|---|---|
| 2026 | $0 | — | −$214M | — |
| 2025 | $0 | — | −$214M | — |
| 2024 | $0 | — | −$151M | — |
| 2023 | $0 | — | −$142M | — |
| 2022 | $0 | — | −$146M | — |
| 2021 | $0 | — | −$131M | — |
| 2020 | $0 | — | −$63M | — |
Growth signals
Latest recorded traffic for Annexon Biosciences is 4.9K monthly website visits, down 41.7% over the last three months. Annexon Biosciences's team declined 2.5% over the past year.
Open positions
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Investments and acquisitions
Recent portfolio relationships for companies that also act as investors or acquirers.
Investors
From Dealroom's funding and investor records, grouped by the round each investor first entered.
Series A4 investors entered at this stage
Novartis Venture Fund
Clarus Ventures
NEA
Correlation Ventures
Series B and later13 investors entered at this stage
Bain Capital Life Sciences
Blackstone
Citadel- SMSatter Investment Management
Bain Capital
Adage Capital
Redmile Group
Farallon Capital Management
Deerfield
Logos Capital
BlackRock
Eventide Asset ManagementJanus Henderson Investors
Other known investors1 additional known investor
Stanford University
Source: Dealroom Talent Intelligence.
Global footprint
team presence
Market sentiment
An AI-synthesised read of the highest-engagement posts about Annexon Biosciences on X, ranked by likes and reposts, corporate channels excluded.
Reading the room on X — pulling top posts and synthesizing themes…
Source: X recent search ranked by engagement (likes + retweets) · Synthesis by Claude · Cached for 1 hour
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