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Aileron Therapeutics

Biotech & Life Sciences · Cambridge, United States · Founded 2005 · IPO 2017

Clinical-stage leader in the field of stapled peptide therapeutics for cancers and other diseases MoreLess

Aileron Therapeutics is a clinical-stage biopharmaceutical company focused on discovering and developing innovative medicines aimed at improving the outcomes and quality of life for cancer patients. The company operates in the biopharmaceutical market, specifically targeting historically undruggable targets with its proprietary platform of stabilized cell-permeating peptides. Aileron's lead product candidate, ALRN-6924, is designed to mimic the p53 tumor suppressor protein, disrupting its interactions with endogenous inhibitors to protect healthy cells during chemotherapy. This approach aims to prevent severe toxicities caused by off-target effects of cancer treatments.

Aileron Therapeutics serves cancer patients undergoing chemotherapy, particularly those with small cell lung cancer (SCLC). The company generates revenue through the development and potential commercialization of its drug candidates, as well as through public offerings of its common stock.

Keywords: biopharmaceutical, cancer, stabilized peptides, p53 protein, chemoprotection, ALRN-6924, clinical-stage, oncology, SCLC, drug development.

Valuation $69M
Total funding $100–500M

Talent graph

Aileron Therapeutics's talent

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Team profiled 20 named & role-tagged
Founders Hidden — book a demo/100 quality score
Key operators 4 quality Hidden — book a demo/100
Potential founders Hidden — book a demo likely future founders
Startup mafia Hidden — book a demo alumni-founded startups
Talent movements Hidden — book a demo in · Hidden — book a demo out past 12 months

Source: Dealroom Talent Intelligence.

Investors

18 investors on Aileron Therapeutics's cap table

Sourced from Dealroom's funding history.

Series A 2 investors entered at this stage
Apple Tree Partners
Novartis Venture Fund
Series B+ 16 investors entered at this stage
SR One
Excel Venture Management
Lilly Ventures
Roche Venture Fund
Aju IB Investment
BVF Partners
Satter Investment Management
Lincoln Park Capital Fund
Acorn Bioventures
Yorkville Advisors
Stonepine Capital Management
ADAR1 Capital Management
Ikarian Capital LLC
Cable Car Capital
Second Line Capital
Bios Partners

Global footprint

Where Aileron Therapeutics has talent and traffic

Workforce by country
2 countries with
team presence
🇺🇸 United States87.5%
🇨🇭 Switzerland12.5%
2 countries shown

Market sentiment

What the market is saying about Aileron Therapeutics

An AI-synthesized read of the highest-engagement posts about Aileron Therapeutics on X over the past 7 days. We rank by likes & retweets, ignore corporate channels, and surface the themes that broke out from real people.

Reading the room on X — pulling top posts and synthesizing themes…

Source: X recent search ranked by engagement (likes + retweets) · Synthesis by Claude · Cached for 1 hour

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