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Xilio Therapeutics

Biotech & Life Sciences · Waltham, United States · Founded 2016 · IPO 2021

Developing its proprietary technology to create a new class of ultra-potent IO therapies that are activated selectively within the tumor MoreLess

Xilio Therapeutics is a biotechnology company focused on developing tumor-activated immuno-oncology therapies designed to provide effective, tolerable, and durable treatment options for patients with solid tumors. The company leverages its proprietary platform technology to create a pipeline of novel molecules, including antibodies, cytokines, bispecifics, and cell engagers, that localize anti-tumor activity within the tumor microenvironment. Xilio's business model centers on research and development, aiming to transform cancer treatment by minimizing systemic side effects and maximizing therapeutic efficacy. The company primarily serves patients with solid tumors, operating in the oncology market. Revenue is generated through partnerships, licensing agreements, and potential future sales of approved therapies. Keywords: tumor-activated, immuno-oncology, solid tumors, antibodies, cytokines, bispecifics, cell engagers, therapeutic index, tumor microenvironment, cancer treatment.

Revenue $36M
Total funding $100–500M

Talent graph

Xilio Therapeutics's talent

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Team profiled 24 named & role-tagged
Founders Hidden — book a demo/100 quality score
Key operators 8 quality Hidden — book a demo/100
Potential founders Hidden — book a demo likely future founders
Startup mafia Hidden — book a demo alumni-founded startups
Talent movements Hidden — book a demo in · Hidden — book a demo out past 12 months

Source: Dealroom Talent Intelligence.

Investors

18 investors on Xilio Therapeutics's cap table

Sourced from Dealroom's funding history. Investor profile links are shown where available.

Series A 10 investors entered at this stage
F-Prime
Atlas Venture
Takeda Ventures
Bay City Capital
Ipsen
M Ventures
RiverVest Venture Partners
SV Health Investors
MRL Ventures
Solasta Ventures
Series B+ 8 investors entered at this stage
Bain Capital Life Sciences
RA Capital Management
Rock Springs Capital
Deerfield
Gilead Sciences
Perceptive Advisors
OrbiMed
Coastlands Capital

Global footprint

Where Xilio Therapeutics has talent and traffic

Workforce by country
🇺🇸 United States · Waltham HQ
Book a demo for the full country breakdown
Web traffic by country
4.5K monthly visits
across markets
🇺🇸 United States95.6%
🇨🇦 Canada4.4%
🇮🇳 India2.2%
Top 3 markets shown

Market sentiment

What the market is saying about Xilio Therapeutics

An AI-synthesized read of the highest-engagement posts about Xilio Therapeutics on X over the past 7 days. We rank by likes & retweets, ignore corporate channels, and surface the themes that broke out from real people.

Reading the room on X — pulling top posts and synthesizing themes…

Source: X recent search ranked by engagement (likes + retweets) · Synthesis by Claude · Cached for 1 hour

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