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Tolerance Bio

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Innovative therapies enhancing immune tolerance by restoring thymus function to combat immune-mediated diseases

Philadelphia, United StatesFounded 2023Biotech & Life Sciences
Valuation $100–250M Last recorded · 2024
Headcount <100 Current team size
Total funding $10–50M Disclosed equity funding
Unlock exact values This page shows ranges. Dealroom has the exact numbers for Tolerance Bio and the history behind them.

About Tolerance Bio

Tolerance Bio is at the forefront of developing innovative therapies aimed at enhancing immune tolerance by restoring and preserving the function of the thymus, a critical organ in the immune system. The company targets immune-mediated diseases, which include cancer, autoimmunity, transplant rejection, infections, immune deficiencies, and allergies. These conditions represent significant unmet medical challenges due to abnormalities in immune tolerance. Tolerance Bio operates in the biotechnology sector, focusing on a multi-platform approach to manipulate thymus function, thereby addressing the root causes of these diseases. The business model involves pioneering novel therapeutics with the potential to rapidly advance and validate concepts in rare diseases, followed by proof of concept in broader indications. Revenue is generated through the development and commercialization of these therapeutics, targeting both niche and major markets. The company serves healthcare providers, researchers, and patients seeking advanced solutions for immune-related conditions.

Source: Dealroom company data

At a glance

Status
Operational
Founded
2023
Headquarters
Philadelphia, United States
Employees
17
Open positions
None listed
Dealroom signal
73.7/100
Industry
Health
Sub-industry
BioTechnology
Sector
Biotech & Life Sciences, Biotechnology, Spinout, Biotech and Pharma, DT and LS, science-based
Business model
Manufacturing
Client focus
b2b

Funding history

4 recorded events

Company financing events and reported valuations.

Deal typeDateAmountValuationInvestorsSource
EARLY VC✓Equity / VC Aug 2026 $0 — NeolmmuneTech ↗
EARLY VC✓Equity / VC Jun 2026 $0 — BCI · Beyond Celiac ↗
Showing the latest 2 of 4 recorded eventsBook a demo for the full funding history →

Growth signals

Tolerance Bio website traffic

Latest recorded traffic for Tolerance Bio is 1.7K monthly website visits, up 13.3% over the last three months. Tolerance Bio's team grew 0% over the past year.

Latest monthly visits1.7K 3-month web change+13.3% 1-year team growth0%
Summary metrics are public; monthly history is available with a demoCompare with peers →

Similar companies

Closest operating peers by Dealroom taxonomy

Company identity and context are open; selected comparison metrics preview what is available on the platform.

Showing 8 of the closest matchesCompare every metric →

Investments and acquisitions

Capital deployed

Recent portfolio relationships for companies that also act as investors or acquirers.

Investors

12 investors on the cap table

From Dealroom's funding and investor records, grouped by the round each investor first entered.

Seed6 investors entered at this stage

  • Columbus Venture Partners
  • Ben Franklin Technology Partners of Northeastern Pennsylvania
  • Criteria Bio Ventures
  • BioAdvance
  • Pacific 8 Ventures
  • Sessa Capital

Series A3 investors entered at this stage

  • BCI
  • Beyond Celiac
  • NeolmmuneTech

Other known investors3 additional known investors

  • University of Colorado
  • University of Colorado Anschutz Medical Campus
  • University of Florida
Team profiled 5 named & role-tagged
Founders Hidden — book a demo/100 quality score
Key operators 3 quality Hidden — book a demo/100
Potential founders Hidden — book a demo likely future founders
Startup mafia Hidden — book a demo alumni-founded startups
Talent movements Hidden — book a demo in · Hidden — book a demo out past 12 months

Source: Dealroom Talent Intelligence.

Global footprint

Workforce and web traffic by country
Workforce by country
3 countries with
team presence
🇺🇸 United States86.7%
🇪🇸 Spain6.7%
🇳🇱 Netherlands6.7%
3 countries shown

Market sentiment

Posts on X, past 7 days

An AI-synthesised read of the highest-engagement posts about Tolerance Bio on X, ranked by likes and reposts, corporate channels excluded.

Reading the room on X — pulling top posts and synthesizing themes…

Source: X recent search ranked by engagement (likes + retweets) · Synthesis by Claude · Cached for 1 hour

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