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Third Harmonic Bio

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Clinical-stage company developing a first-in-class, highly selective, oral KIT inhibitor for treatment of severe allergy and inflammation

Cambridge, United StatesFounded 2019Biotech & Life Sciences
Valuation $100–250M Last recorded · 2025
Headcount <100 Current team size
Total funding $100–500M Disclosed equity funding
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About Third Harmonic Bio

Third Harmonic Bio, Inc. is a clinical-stage biopharmaceutical company dedicated to developing novel therapeutics for inflammatory diseases affecting the skin, respiratory system, and gastrointestinal tract. The company focuses on advancing THB335, a highly selective, oral small molecule wild type KIT inhibitor, aimed at treating chronic urticaria, severe asthma, and other mast cell-mediated inflammatory conditions. Third Harmonic Bio operates within the biopharmaceutical market, primarily serving patients suffering from these chronic conditions. The business model revolves around the research, development, and eventual commercialization of its proprietary treatments. Revenue generation is expected through the successful development and market introduction of its therapeutic products. The company is committed to improving patient outcomes by providing innovative and effective treatment options.

Source: Dealroom company data

At a glance

Founded
2019
Headquarters
Cambridge, United States
Sector
Biotech & Life Sciences

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Investors

10 investors on the cap table

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Series A10 investors entered at this stage

Talent

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Team profiled 5 named & role-tagged
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Key operators 2 quality Hidden — book a demo/100
Potential founders Hidden — book a demo likely future founders
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Source: Dealroom Talent Intelligence.

Global footprint

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