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Talus Bioscience
Discovers first-in-class inhibitors for previously undruggable targets, starting with pediatric cancers
About Talus Bioscience
Talus Bioscience, Inc., based in Seattle, WA, is a pioneering startup focused on revolutionizing drug development, particularly for transcription factors. Transcription factors are proteins that help turn specific genes on or off by binding to nearby DNA. These proteins hold immense potential for treating a variety of diseases, including cancer and diabetes. However, only a few transcription factor-targeting drugs have been approved to date.
Talus Bio's flagship platform, MARMOT, is the first of its kind to target transcription factors in their natural cellular environments. This innovative approach allows for more accurate and effective drug discovery. The company operates in the biotechnology and pharmaceutical markets, serving clients such as pharmaceutical companies, research institutions, and healthcare providers who are looking to develop new and effective treatments for challenging diseases.
The business model of Talus Bio revolves around leveraging its advanced platform to discover and develop new drugs. They generate revenue through partnerships, licensing agreements, and potentially through the sale of newly developed drugs. Their approach integrates cutting-edge technologies such as automated cell processing, next-generation proteomics (the large-scale study of proteins), and advanced data analytics to measure a drug's effect on the entire regulome (the complete set of regulatory components in a cell).
Talus Bio's team is highly interdisciplinary, comprising experts in medicinal chemistry, molecular biology, cancer research, mass spectrometry, computational science, and machine learning. This diverse expertise positions them uniquely to tackle the complex challenges of transcription factor drug discovery.
In summary, Talus Bioscience is at the forefront of developing new treatments for diseases by targeting transcription factors in their native environments, using a combination of advanced technologies and a highly skilled team.
Source: Dealroom company dataAt a glance
- Status
- Operational
- Founded
- 2020
- Headquarters
- Seattle, United States
- Employees
- 29
- Open positions
- None listed
- Dealroom signal
- 79.8/100
- Industry
- Health
- Sub-industry
- BioTechnology
- Sector
- Biotech & Life Sciences, Biotechnology, Spinout, Biotech and Pharma, YC S21, proteomics, DT and LS, science-based
- Business model
- Manufacturing
- Client focus
- b2b
Knowledge graph
More headlines
Funding history
Company financing events and reported valuations.
| Deal type | Date | Amount | Valuation | Investors | Source |
|---|---|---|---|---|---|
| GRANT✓Other financing | Jul 2026 | $1M | — | National Center For Advancing Translational Sciences | ↗ |
| SEED✓Equity / VC | Aug 2024 | $11M | $45M | Y Combinator · Two Bear Capital · FundersClub · BoxOne Ventures | ↗ |
Growth signals
Latest recorded traffic for Talus Bioscience is 4.4K monthly website visits, up 33.3% over the last three months. Talus Bioscience's team grew 11.5% over the past year.
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Investments and acquisitions
Recent portfolio relationships for companies that also act as investors or acquirers.
Investors
From Dealroom's funding and investor records, grouped by the round each investor first entered.
Seed8 investors entered at this stage
Y Combinator
US National Science Foundation
FundersClub
National Institutes of Health
Two Bear Capital
BoxOne Ventures
WRF Capital
National Center For Advancing Translational Sciences
Series A1 investor entered at this stage
Other known investors10 additional known investors
Altius Institute for Biomedical Sciences
University of Washington
Axial VC
Creative Destruction Lab
Farvatn Venture
Fifty Years
North South Ventures
Pioneer Fund
Reinforced Ventures
Small Business Innovation Research
Source: Dealroom Talent Intelligence.
Global footprint
team presence
Market sentiment
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