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Talus Bioscience

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Discovers first-in-class inhibitors for previously undruggable targets, starting with pediatric cancers

Seattle, United StatesFounded 2020Biotech & Life Sciences
Valuation $50–100M Last recorded · 2024
Headcount <100 Current team size
Total funding $10–50M Disclosed equity funding
Unlock exact values This page shows ranges. Dealroom has the exact numbers for Talus Bioscience and the history behind them.

About Talus Bioscience

Talus Bioscience, Inc., based in Seattle, WA, is a pioneering startup focused on revolutionizing drug development, particularly for transcription factors. Transcription factors are proteins that help turn specific genes on or off by binding to nearby DNA. These proteins hold immense potential for treating a variety of diseases, including cancer and diabetes. However, only a few transcription factor-targeting drugs have been approved to date.

Talus Bio's flagship platform, MARMOT, is the first of its kind to target transcription factors in their natural cellular environments. This innovative approach allows for more accurate and effective drug discovery. The company operates in the biotechnology and pharmaceutical markets, serving clients such as pharmaceutical companies, research institutions, and healthcare providers who are looking to develop new and effective treatments for challenging diseases.

The business model of Talus Bio revolves around leveraging its advanced platform to discover and develop new drugs. They generate revenue through partnerships, licensing agreements, and potentially through the sale of newly developed drugs. Their approach integrates cutting-edge technologies such as automated cell processing, next-generation proteomics (the large-scale study of proteins), and advanced data analytics to measure a drug's effect on the entire regulome (the complete set of regulatory components in a cell).

Talus Bio's team is highly interdisciplinary, comprising experts in medicinal chemistry, molecular biology, cancer research, mass spectrometry, computational science, and machine learning. This diverse expertise positions them uniquely to tackle the complex challenges of transcription factor drug discovery.

In summary, Talus Bioscience is at the forefront of developing new treatments for diseases by targeting transcription factors in their native environments, using a combination of advanced technologies and a highly skilled team.

Source: Dealroom company data

At a glance

Status
Operational
Founded
2020
Headquarters
Seattle, United States
Employees
29
Open positions
None listed
Dealroom signal
79.8/100
Industry
Health
Sub-industry
BioTechnology
Sector
Biotech & Life Sciences, Biotechnology, Spinout, Biotech and Pharma, YC S21, proteomics, DT and LS, science-based
Business model
Manufacturing
Client focus
b2b

Funding history

9 recorded events

Company financing events and reported valuations.

Deal typeDateAmountValuationInvestorsSource
GRANT✓Other financing Jul 2026 $1M — National Center For Advancing Translational Sciences ↗
SEED✓Equity / VC Aug 2024 $11M $45M Y Combinator · Two Bear Capital · FundersClub · BoxOne Ventures ↗
Showing the latest 2 of 9 recorded eventsBook a demo for the full funding history →

Growth signals

Talus Bioscience website traffic

Latest recorded traffic for Talus Bioscience is 4.4K monthly website visits, up 33.3% over the last three months. Talus Bioscience's team grew 11.5% over the past year.

Latest monthly visits4.4K 3-month web change+33.3% 1-year team growth+11.5%
Summary metrics are public; monthly history is available with a demoCompare with peers →

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Closest operating peers by Dealroom taxonomy

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CatenaBioCatena biosciences's mission is to create new therapies for cancer, vaccines, and to retrain the immune system to cure autoimmune disorders Berkeley, United States Operational 18 $4.8M $9.4M
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Stratus TherapeuticsDeveloping off-the-shelf hematopoietic stem cell (HSC) therapies to treat a broad range of severe and life-threatening diseases Natick, United States Operational
Nabla BioDeveloping AI and wet-lab technologies to enable the rational design of selective, functional drugs targeting previously undruggable sites Cambridge, United States Operational
Nereid TherapeuticsA pioneer of the biomolecular condensate field and one of the world’s leading experts in intracellular liquid-liquid phase separation Boston, United States Operational
Aperiam BioTaking the guesswork out of biotechnology with computer vision that illuminates critical parts of protein chemistry New York City, United States Operational
PRAMOMOLECULARDeveloping innovative self-delivering siRNAs to silence the formation of disease-causing proteins to improve the treatment of lung and pancreatic cancer Berlin, Germany Operational
Juvena TherapeuticsA biopharmaceutical platform which is discovering novel protein-based therapeutics Palo Alto, United States Operational
Showing 8 of the closest matchesCompare every metric →

Investments and acquisitions

Capital deployed

Recent portfolio relationships for companies that also act as investors or acquirers.

Investors

19 investors on the cap table

From Dealroom's funding and investor records, grouped by the round each investor first entered.

Seed8 investors entered at this stage

  • Y Combinator
  • US National Science Foundation
  • FundersClub
  • National Institutes of Health
  • Two Bear Capital
  • BoxOne Ventures
  • WRF Capital
  • National Center For Advancing Translational Sciences

Series A1 investor entered at this stage

Other known investors10 additional known investors

Team profiled 9 named & role-tagged
Founders Hidden — book a demo/100 quality score
Key operators 3 quality Hidden — book a demo/100
Potential founders Hidden — book a demo likely future founders
Startup mafia Hidden — book a demo alumni-founded startups
Talent movements Hidden — book a demo in · Hidden — book a demo out past 12 months

Source: Dealroom Talent Intelligence.

Global footprint

Workforce and web traffic by country
Workforce by country
1 countries with
team presence
🇺🇸 United States100%
1 country shown

Market sentiment

Posts on X, past 7 days

An AI-synthesised read of the highest-engagement posts about Talus Bioscience on X, ranked by likes and reposts, corporate channels excluded.

Reading the room on X — pulling top posts and synthesizing themes…

Source: X recent search ranked by engagement (likes + retweets) · Synthesis by Claude · Cached for 1 hour

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