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Si-Bone

Health Tech & Medtech · San Jose, United States · Founded 2008 · IPO 2018

Develops an implant to tackle lower back pains MoreLess

SI-BONE was founded with a mission to address a significant unmet need in the orthopedic field. The company was established by Dr. Mark Reiley, a renowned orthopedic surgeon, who identified the potential to improve treatments for sacroiliac joint dysfunction, a common source of lower back pain. Alongside co-founders Jeff Dunn and Laura Francis, Dr. Reiley set out to revolutionize the approach to this condition.

In its early days, SI-BONE focused on developing a minimally invasive surgical implant system known as iFuse. This system was designed to provide a less invasive option for patients suffering from sacroiliac joint dysfunction, offering a quicker recovery time compared to traditional surgical methods.

The company's journey was marked by significant milestones, including securing FDA clearance for its iFuse Implant System. This regulatory approval was a critical step that allowed SI-BONE to expand its reach and impact in the medical community.

In 2018, SI-BONE achieved a major milestone by going public. The company's Initial Public Offering (IPO) on the NASDAQ provided the capital needed to further its research and development efforts and expand its market presence. This move not only validated SI-BONE's innovative approach but also positioned it for future growth in the competitive medical device industry.

Today, SI-BONE continues to lead in the field of sacroiliac joint treatment, driven by a commitment to improving patient outcomes through innovation and education. The company's journey from a visionary idea to a publicly traded entity underscores its role as a pioneer in orthopedic solutions.

Valuation $686M
Revenue $232M
Total funding $100–500M

Talent graph

Si-Bone's talent

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Team profiled 27 named & role-tagged
Founders Hidden — book a demo/100 quality score
Key operators 5 quality Hidden — book a demo/100
Potential founders Hidden — book a demo likely future founders
Startup mafia Hidden — book a demo alumni-founded startups
Talent movements Hidden — book a demo in · Hidden — book a demo out past 12 months

Source: Dealroom Talent Intelligence.

Investors

8 investors on Si-Bone's cap table

Sourced from Dealroom's funding and investor records. Investor profile links are shown where available.

Series A 1 investor entered at this stage
Skyline Ventures
Series B+ 7 investors entered at this stage
Montreux Equity Partners
Novo Seeds
OrbiMed
Novo Ventures
Redline Capital
Arboretum Ventures
Armentum Partners

Global footprint

Where Si-Bone has talent and traffic

Workforce by country
10 countries with
team presence
🇺🇸 United States92.9%
🇮🇹 Italy2.4%
🇩🇪 Germany1.3%
🇫🇷 France1.1%
🇬🇧 United Kingdom0.5%
Top 5 of 10 shown
Web traffic by country
53K monthly visits
across markets
🇺🇸 United States67.5%
🇨🇦 Canada20.6%
🇬🇧 United Kingdom4.5%
🇮🇳 India2.8%
🇦🇺 Australia2.6%
Top 5 markets shown

Patent intelligence

$39M patent portfolio · 31 active families

Estimated portfolio value
$39M
5.7% of market cap · 88.2× smaller than top peer Mazor Robotics ($3.5B)
31 active patent families
Where Si-Bone innovates Biomedical engineeringBone fixationBones fixationGeneral surgeryImplant

Where Si-Bone concentrates vs peers

Each axis is a top-10 topic across Si-Bone and its closest peers. #1 = 100, #10 = 10, absent = 0.

Compare against

Source: Dealroom Patent Intelligence · Patsnap. Request a demo for the full per-sub-category breakdown, individual records, and quality-score history.

Market sentiment

What the market is saying about Si-Bone

An AI-synthesized read of the highest-engagement posts about Si-Bone on X over the past 7 days. We rank by likes & retweets, ignore corporate channels, and surface the themes that broke out from real people.

Reading the room on X — pulling top posts and synthesizing themes…

Source: X recent search ranked by engagement (likes + retweets) · Synthesis by Claude · Cached for 1 hour

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