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Sequence Holdings
AI and engineering for acquired American businesses.
About Sequence Holdings
Sequence Holdings is a permanent holding company that acquires American businesses with the aim of integrating artificial intelligence and advanced engineering at their core. Founded by Michael Lee, Neal Wu, and Alex Rubin, the firm operates out of New York and the San Francisco Bay Area. The leadership team brings experience from prominent organizations such as Scale, Palantir, Lone Pine, and Silver Lake.
The company's business model is centered on long-term value creation through strategic partnerships with established businesses. Sequence Holdings provides capital, operational expertise, and technology solutions to drive growth and industry leadership within its portfolio companies. Unlike typical private equity firms, it operates with a permanent timeframe, focusing on sustained development rather than short-term exits.
In March 2026, Sequence Holdings announced it had raised approximately $75 million in a Series A funding round. Key investors include Lux, Conviction, 8VC, Factory, Definition Capital, and Avenir. This capital is earmarked for expanding its portfolio by identifying and investing in high-potential companies and enhancing its capacity to deliver operational and technological support.
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Other known investors1 additional known investor
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