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Second Genome
Offers a pipeline of microbiome modulators that impact infection, immunity and metabolic diseases
About Second Genome
Second Genome is a biotechnology startup that operates in the pharmaceutical industry, specializing in the discovery and development of precision therapies. The company uses a unique approach that extends beyond traditional human biology to identify potential drug targets and therapies. This approach is supported by a suite of proprietary tools and capabilities that allow for mass data integration, machine learning, and strain-level identification, which are all unique to Second Genome.
The company's primary focus is on inflammatory bowel disorders and solid tumors. It has two advanced programs in IND-enabling studies and eight additional programs in early discovery. Its lead development candidate, SG-5-00455, has shown potential to become the first in its class to directly target mucosal healing in patients with inflammatory bowel disease (IBD). Another promising candidate, SG-3-06686, has demonstrated potential as a first-in-class CXCR3 immune activator that can inhibit tumor growth.
Second Genome's business model revolves around the discovery of novel therapeutics and biomarkers, which are then patented (IP filed) for potential commercialization. The company also collaborates with other businesses, as evidenced by its multi-year collaboration with Bayer, where it discovered diverse and novel proteins for potential development of next-generation insect-control products.
In terms of revenue, Second Genome likely earns money through the licensing of its proprietary technologies, partnerships with other pharmaceutical companies, and potentially, the sale of its developed drugs once they receive regulatory approval.
Source: Dealroom company dataAt a glance
- Status
- Operational
- Founded
- 2009
- Headquarters
- South San Francisco, United States
- Employees
- 4
- Open positions
- None listed
- Dealroom signal
- 62.5/100
- Industry
- Health
- Sub-industry
- BioTechnology
- Sector
- Biotech & Life Sciences, Biotechnology, DNA, Genetics and genomics, Microbiology, Nutrition, Spinout, Biotech and Pharma, DT and LS, science-based
- Client focus
- b2b
Knowledge graph
More headlines
Funding history
Company financing events and reported valuations.
Growth signals
Latest recorded traffic for Second Genome is 200 monthly website visits, down 80% over the last three months. Second Genome's team declined 33.3% over the past year.
Similar companies
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Investments and acquisitions
Recent portfolio relationships for companies that also act as investors or acquirers.
Investors
From Dealroom's funding and investor records, grouped by the round each investor first entered.
Series A10 investors entered at this stage
- MVMorgenthaler Ventures
- AVAdvanced Technology Ventures
SR One
Matthew Winkler- ADAdveq
Digitalis Ventures
Mayo Clinic
Roche Venture Fund
Seraph Group- MCMBL Venture Capital
Other known investors1 additional known investor
Berkeley Lab
Source: Dealroom Talent Intelligence.
Global footprint
team presence
Market sentiment
An AI-synthesised read of the highest-engagement posts about Second Genome on X, ranked by likes and reposts, corporate channels excluded.
Reading the room on X — pulling top posts and synthesizing themes…
Source: X recent search ranked by engagement (likes + retweets) · Synthesis by Claude · Cached for 1 hour
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