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Inspirna
Biotechnology company developing drugs for the treatment of cancer
About Inspirna
Rgenix, operating under the name Inspirna, is a biotech startup that focuses on developing innovative treatments for common, previously untreatable cancers. The company's primary approach is to identify new drivers of cancer metastasis, which are the factors that cause cancer to spread within the body. They do this through their proprietary RNA-DRIVEr™ platform and microRNA mapping. The RNA-DRIVEr™ platform is a clinically-validated tool that helps to discover previously unknown factors that drive cancer growth and spread.
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Inspirna's business model revolves around the development and commercialization of small molecules and biologics, which are types of drugs used in cancer treatment. The company's main clients are patients suffering from common cancers, particularly colorectal and non-small cell lung cancer.
Inspirna's revenue comes from the development and sale of these drugs. Currently, the company has two drugs in the pipeline. The first, ompenaclid (RGX-202), is in Phase 2 development for patients with RAS mutant colorectal cancer. The second, abequolixron (RGX-104), is in Phase 1b/2 development for patients with non-small cell lung cancer and endometrial cancer.
Inspirna's goal is to make cancer a manageable, chronic condition by providing more practical treatment options that prolong survival without decreasing patients’ quality of life. The company aims to develop medicines with oral dosing and safety profiles that can easily be incorporated into existing standard-of-care treatments.
At a glance
- Status
- Operational
- Founded
- 2010
- Headquarters
- New York City, United States
- Employees
- 8
- Open positions
- None listed
- Dealroom signal
- 61.8/100
- Industry
- Health
- Sub-industry
- Pharmaceutical, BioTechnology
- Sector
- Biotech & Life Sciences, Intellectual Property, Risk Management, Biotechnology, Oncology, Drug Development, DNA, Surgery, Genetics and genomics, Antibodies, Immune System
- Business model
- Manufacturing
Latest news
Press, funding announcements and product moves mentioning Inspirna.
Funding history
Company financing events and reported valuations.
| Deal type | Date | Amount | Valuation | Investors | Source |
|---|---|---|---|---|---|
| SERIES DOther financing | Jul 2022 | $50M | $200M | Dreavent 6 · Novo Holdings · Vivo Capital · The New York City Investment Fund | ↗ |
| SERIES COther financing | Oct 2018 | $40M | $160M | Sofinnova Partners · Partnership Fund for New York City · WuXi AppTec · Novo Holdings | — |
Growth signals
Latest recorded traffic for Inspirna is 180 monthly website visits, down 82% over the last three months. Inspirna's team declined 38.5% over the past year.
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Investors
From Dealroom's funding and investor records, grouped by the round each investor first entered.
Seed2 investors entered at this stage
Arya Bolurfrushan
Small Business Innovation Research
Series A3 investors entered at this stage
Paolo Rubatto
Novo Holdings
Sofinnova Partners
Series B and later10 investors entered at this stage
Partnership Fund for New York City
WuXi AppTec
Alexandria Venture Investments
Oceanpine Capital- D6Dreavent 6
Vivo Capital- TFThe New York City Investment Fund
Sofinnova Investments
Lepu Medical
Sixty Degree Capital
Other known investors1 additional known investor
Rockefeller University
Source: Dealroom Talent Intelligence.
Global footprint
team presence
Market sentiment
An AI-synthesised read of the highest-engagement posts about Inspirna on X, ranked by likes and reposts, corporate channels excluded.
Reading the room on X — pulling top posts and synthesizing themes…
Source: X recent search ranked by engagement (likes + retweets) · Synthesis by Claude · Cached for 1 hour
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