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Replicate Bioscience

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Developing next-gen self-replicating RNA treatments for infectious diseases, oncology, and autoimmune disorders

San Diego, United StatesFounded 2021Biotech & Life Sciences
Valuation $100–250M Last recorded · 2021
Headcount <100 Current team size
Total funding $10–50M Disclosed equity funding
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About Replicate Bioscience

Replicate Bioscience is a cutting-edge biotechnology startup focused on developing advanced RNA-based treatments. The company specializes in self-replicating RNA (srRNA) therapies, which are designed to treat a variety of medical conditions, including infectious diseases, cancer (oncology), and autoimmune disorders. Unlike traditional linear mRNA treatments, srRNA therapies offer improved performance by driving repeated production of natural RNA within cells, leading to higher protein expression and more durable therapeutic effects.

Replicate Bioscience operates in the biopharmaceutical market, targeting both healthcare providers and patients who require innovative treatments for complex diseases. The company's business model revolves around research and development (R&D) of srRNA therapies, which are then brought to market either through direct commercialization or partnerships with larger pharmaceutical companies. Revenue is generated through the sale of these therapies, licensing agreements, and potentially through milestone payments and royalties from partnered products.

The company boasts a robust pipeline of srRNA treatments, backed by a team of experts in RNA technology and immunology. Collaborations with renowned institutions like Duke University further strengthen its R&D capabilities. With a customizable library of synthetic srRNA vectors and comprehensive development capabilities, Replicate Bioscience is well-positioned to create safe and effective immunotherapies that can significantly impact patient outcomes.

In summary, Replicate Bioscience is a pioneering biotech firm leveraging next-generation srRNA technology to develop treatments for infectious diseases, cancer, and autoimmune disorders. Its innovative approach and strategic partnerships aim to maximize therapeutic impact and improve patient care.

Source: Dealroom company data

At a glance

Status
Operational
Founded
2021
Headquarters
San Diego, United States
Employees
22
Open positions
None listed
Dealroom signal
72.5/100
Industry
Health
Sub-industry
BioTechnology
Sector
Biotech & Life Sciences, Biotechnology, Spinout, Biotech and Pharma, proteomics, DT and LS, science-based
Business model
Manufacturing
Client focus
b2b

Funding history

4 recorded events

Company financing events and reported valuations.

Deal typeDateAmountValuationInvestorsSource
GRANT✓Other financing Jun 2026 $3M — Bill & Melinda Gates Foundation ↗
SERIES A✓Equity / VC Sep 2021 $40M $160M Apple Tree Partners —
Showing the latest 2 of 4 recorded eventsBook a demo for the full funding history →

Growth signals

Replicate Bioscience website traffic

Latest recorded traffic for Replicate Bioscience is 2.1K monthly website visits, up 40% over the last three months. Replicate Bioscience's team grew 10% over the past year.

Latest monthly visits2.1K 3-month web change+40% 1-year team growth+10%
Summary metrics are public; monthly history is available with a demoCompare with peers →

Similar companies

Closest operating peers by Dealroom taxonomy

Company identity and context are open; selected comparison metrics preview what is available on the platform.

CompanyHeadquartersStatusEmployeesTotal fundingValuation
Guangdong Maijinjia BiotechnologyInnovative nucleic acid drug technologies for gene-specific protein upregulation, addressing high unmet medical needs Guangzhou, China Operational — $2.8M $11M
InnoRNAProprietary LNP platform for effective mRNA delivery, enabling advanced nucleic acid therapeutics Shenzhen, China Operational
76bioDegradation by design 76Bio aims to develop transformational therapies for patients with life-threatening disease by pioneering the next generation of New York City, United States Operational
BridGene BiosciencesBiotechnology company using cutting-edge chemoproteomic technology to discover and develop small molecules San Jose, United States Operational
Outpace BioRevolutionizing cell therapy with protein design, Outpace reprograms immune cells to make better decisions inside patients, enhancing cell therapy persistence and overcoming biology barriers to cancer treatment Seattle, United States Operational
Avenge BioFocusing cell generated immunotherapies to eradicate solid tumors Foxborough, United States Operational
Monte Rosa TherapeuticsDeveloping next-generation small molecule protein degraders to treat cancer and beyond Boston, United States Operational
ThryvDiscovering and developing therapies for the treatment of Long QT syndrome Laval, Canada Operational
Showing 8 of the closest matchesCompare every metric →

Investments and acquisitions

Capital deployed

Recent portfolio relationships for companies that also act as investors or acquirers.

Investors

3 investors on the cap table

From Dealroom's funding and investor records, grouped by the round each investor first entered.

Seed2 investors entered at this stage

  • Apple Tree Partners
  • Bill & Melinda Gates Foundation

Other known investors1 additional known investor

  • Duke University
Team profiled 7 named & role-tagged
Founders Hidden — book a demo/100 quality score
Key operators 5 quality Hidden — book a demo/100
Potential founders Hidden — book a demo likely future founders
Startup mafia Hidden — book a demo alumni-founded startups
Talent movements Hidden — book a demo in · Hidden — book a demo out past 12 months

Source: Dealroom Talent Intelligence.

Global footprint

Workforce and web traffic by country
Workforce by country
1 countries with
team presence
🇺🇸 United States100%
1 country shown

Market sentiment

Posts on X, past 7 days

An AI-synthesised read of the highest-engagement posts about Replicate Bioscience on X, ranked by likes and reposts, corporate channels excluded.

Reading the room on X — pulling top posts and synthesizing themes…

Source: X recent search ranked by engagement (likes + retweets) · Synthesis by Claude · Cached for 1 hour

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