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Reneo Pharmaceuticals

Biotech & Life Sciences · Irvine, United States · Founded 2017 · IPO 2021

Focused on the development of therapies for patients with genetically defined orphan diseases MoreLess

Reneo Pharmaceuticals is a clinical-stage pharmaceutical company dedicated to developing therapies for rare genetic metabolic disorders. The company primarily focuses on conditions such as McArdle disease and primary mitochondrial myopathies (PMMs), which are characterized by severe muscle pain, weakness, and activity intolerance due to genetic mutations affecting muscle glycogen and mitochondrial function. Reneo's lead investigational compound, REN001, aims to enhance cellular energy metabolism by regulating genes involved in mitochondrial activity.

Reneo serves patients suffering from these rare diseases, operating in the biopharmaceutical market. The company's business model revolves around the research, development, and eventual commercialization of its therapeutic compounds. Revenue generation is anticipated through the successful approval and sale of these therapies, as well as potential partnerships and licensing agreements with larger pharmaceutical firms.

Keywords: rare diseases, genetic disorders, metabolic disorders, McArdle disease, mitochondrial myopathies, REN001, cellular energy, biopharmaceutical, clinical-stage, therapeutic development.

Valuation $154M
Revenue $375K
Total funding $100–500M

Company overview

Reneo Pharmaceuticals company information

The essential company record, classifications and operating signals in one place.

Status
Acquired
Founded
2017
Headquarters
Irvine, United States
Employees
13
Open positions
None listed
Dealroom signal
32.2
client focusb2bsub industryPharmaceuticalsub industryBioTechnologybusiness modelManufacturingindustryHealthsectorDeveloper ToolssectorBiotechnologysectorGenetics and genomicssectorDiseasesectorBiotech and PharmasectorHard TechsectorDT and LSsectorscience-based

Valuation & funding

Reneo Pharmaceuticals funding history

Company financing events and reported valuations.

Deal typeDateAmountValuationInvestorsSource
ACQUISITIONOther financing May 2024 $0 OnKure
POST IPO EQUITYOther financing May 2024 $65M Samsara BioCapital · Surveyor Capital · Vestal Point Capital · Cormorant Asset Management
POST IPO EQUITYOther financing May 2023 $55M Undisclosed
POST IPO SECONDARYOther financing May 2022 $20M Undisclosed
IPOOther financing Apr 2021 $94M $94M Undisclosed
SERIES BOther financing Dec 2020 Novo Ventures · NEA · Aisling Capital · Pappas Capital
SERIES AOther financing May 2019 Lundbeckfonden Ventures · Pappas Capital · NEA
Showing 7 recorded eventsUnlock the complete deal history →

Financials

Revenue, earnings and profit over time

Reported history and available estimates. Estimated years are marked “E”; sparse fields are left blank rather than inferred.

YearRevenueGrowthEBITDAMargin
2026 $375K −$83M -22102.1%
2025 $0 −$83M
2024 $0 −$83M
2023 $0 −$83M
2022 $0 −$54M
2021 $0 −$40M
2020 $0 −$20M
Company filings, research estimates and Dealroom dataOpen the full financial model →

Growth signals

Reneo Pharmaceuticals website traffic

Latest recorded traffic for Reneo Pharmaceuticals is 8.5K monthly website visits, up 12042.9% over the last three months. Reneo Pharmaceuticals's team declined 53.6% over the past year.

Latest monthly visits8.5K 3-month web change+12042.9% 1-year team growth-53.6%
Monthly website visits81 observations · May 2018–Mar 2026
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Comparisons

Reneo Pharmaceuticals compared with similar companies

Dealroom’s weighted taxonomy model identifies the closest operating peers. Company identity and context stay open; selected comparison metrics preview what is available in the platform.

Showing 8 of the closest matchesCompare every metric →

Talent graph

Reneo Pharmaceuticals's talent

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Team profiled 7 named & role-tagged
Founders Hidden — book a demo/100 quality score
Key operators 3 quality Hidden — book a demo/100
Potential founders Hidden — book a demo likely future founders
Startup mafia Hidden — book a demo alumni-founded startups
Talent movements Hidden — book a demo in · Hidden — book a demo out past 12 months

Source: Dealroom Talent Intelligence.

Investors

17 investors on Reneo Pharmaceuticals's cap table

Sourced from Dealroom's funding and investor records. Investor profile links are shown where available.

Series A 9 investors entered at this stage
NEA
Lundbeckfonden Ventures
Pappas Capital
Abingworth
Novo Ventures
Aisling Capital
RiverVest Venture Partners
Rock Springs Capital
Amzak Health Investors
Series B+ 7 investors entered at this stage
Samsara BioCapital
Surveyor Capital
Vestal Point Capital
Cormorant Asset Management
Perceptive Advisors
Acorn Bioventures
Deep Track Capital
Other known 1 additional known investor
OnKure

Global footprint

Where Reneo Pharmaceuticals has talent and traffic

Workforce by country
🇺🇸 United States · Irvine HQ
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In the news

Latest news about Reneo Pharmaceuticals

Recent press, funding announcements, and product moves mentioning Reneo Pharmaceuticals — open to read from the original sources.

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Market sentiment

What the market is saying about Reneo Pharmaceuticals

An AI-synthesized read of the highest-engagement posts about Reneo Pharmaceuticals on X over the past 7 days. We rank by likes & retweets, ignore corporate channels, and surface the themes that broke out from real people.

Reading the room on X — pulling top posts and synthesizing themes…

Source: X recent search ranked by engagement (likes + retweets) · Synthesis by Claude · Cached for 1 hour

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