ReadCoor

About ReadCoor

ReadCoor is a biotechnology startup that has developed a unique platform for gene analysis. The company's technology uses a method called padlock probe rolling circle amplification chemistry, which is a highly sensitive and specific way of identifying and analyzing genes. This method allows for high sensitivity across a broad range of gene expression, including those that are low expressing or highly degraded. It also has the ability to distinguish between similar genes, such as isoforms.

The company's technology works in four steps. First, the probe arms must stably hybridize to their target gene. If only one arm hybridizes, the probe is unstable and will be washed off. The probes also contain a gene-specific barcode sequence that is used to generate a unique optical signature of each gene. Second, only when both probe arms are stably hybridized to the target with a perfect match does proximal probe ligation occur. Third, only ligated probes are amplified, which enriches for true target recognition events and suppresses off-target events. Finally, the amplified products in the samples undergo successive rounds of fluorescent probe hybridization, imaging, and removal. An optical signature specific to each gene is generated.

ReadCoor's clients are likely to be in the scientific and medical research fields, where gene analysis is crucial. The company operates in the biotechnology market and its business model is likely based on selling its technology and services to these clients. It makes money by providing a unique, highly sensitive and specific method of gene analysis.