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Plexium

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A drug development startup that leverages techniques from various physical-science and computational disciplines

San Diego, United StatesFounded 2017Biotech & Life Sciences
Valuation $500M–1B Last recorded · 2025
Headcount <100 Current team size
Total funding $100–500M Disclosed equity funding
Unlock exact values This page shows ranges. Dealroom has the exact numbers for Plexium and the history behind them.

About Plexium

Plexium is a biotech startup that operates in the field of targeted protein degradation (TPD), a promising area of drug discovery. The company's primary focus is on the development of next-generation TPD drugs that can target and degrade disease-causing proteins in the body. These drugs have potential applications in a wide range of therapeutic areas, including cancer and other serious diseases.

Plexium's unique selling point is its proprietary high-throughput cell-based screening technology. This technology allows the company to rapidly test and identify compounds that can degrade target proteins in a disease-relevant environment. This accelerates the drug discovery process and increases the chances of finding effective treatments.

The company's business model revolves around the development and commercialization of its TPD drugs. Plexium generates revenue through the sale of these drugs once they have been approved by regulatory bodies. Additionally, the company also partners with other biotech and pharmaceutical companies to develop and commercialize new drugs, providing another source of income.

Plexium's clients are primarily patients suffering from diseases that can be treated with TPD drugs. However, the company also serves the broader medical community by providing new treatment options and contributing to the advancement of medical science.

In summary, Plexium is a pioneering biotech company that is pushing the boundaries of targeted protein degradation to improve lives. Its unique technology and innovative approach to drug discovery make it a promising player in the biotech industry.

Source: Dealroom company data

At a glance

Status
Operational
Founded
2017
Headquarters
San Diego, United States
Employees
36
Open positions
None listed
Dealroom signal
63.0/100
Industry
Health
Sub-industry
BioTechnology, Health Platform
Sector
Biotech & Life Sciences, Biotechnology, Oncology, Drug Development, Spinout, Tech for Biotech and Pharma, Biotech and Pharma, proteomics, DT and LS, science-based
Business model
Manufacturing
Client focus
b2b

Funding history

8 recorded events

Company financing events and reported valuations.

Deal typeDateAmountValuationInvestorsSource
LATE VCOther financing Aug 2025 $60M $510M Undisclosed ↗
LATE VCOther financing Feb 2022 $102M $408M CRV · Pivotal Life Sciences · Neotribe · M Ventures ↗
Showing the latest 2 of 8 recorded eventsBook a demo for the full funding history →

Growth signals

Plexium website traffic

Latest recorded traffic for Plexium is 5.7K monthly website visits, up 111.1% over the last three months. Plexium's team declined 29.4% over the past year.

Latest monthly visits5.7K 3-month web change+111.1% 1-year team growth-29.4%
Summary metrics are public; monthly history is available with a demoCompare with peers →

Similar companies

Closest operating peers by Dealroom taxonomy

Company identity and context are open; selected comparison metrics preview what is available on the platform.

Showing 8 of the closest matchesCompare every metric →

Investments and acquisitions

Capital deployed

Recent portfolio relationships for companies that also act as investors or acquirers.

Investors

14 investors on the cap table

From Dealroom's funding and investor records, grouped by the round each investor first entered.

Seed2 investors entered at this stage

Series A2 investors entered at this stage

  • The Column Group
  • M Ventures

Series B and later9 investors entered at this stage

Other known investors1 additional known investor

  • Scripps Translational Science Institute
Team profiled 23 named & role-tagged
Founders Hidden — book a demo/100 quality score
Key operators 2 quality Hidden — book a demo/100
Potential founders Hidden — book a demo likely future founders
Startup mafia Hidden — book a demo alumni-founded startups
Talent movements Hidden — book a demo in · Hidden — book a demo out past 12 months

Source: Dealroom Talent Intelligence.

Global footprint

Workforce and web traffic by country
Workforce by country
3 countries with
team presence
🇺🇸 United States95.1%
🇩🇪 Germany2.4%
🇬🇧 United Kingdom2.4%
3 countries shown

Market sentiment

Posts on X, past 7 days

An AI-synthesised read of the highest-engagement posts about Plexium on X, ranked by likes and reposts, corporate channels excluded.

Reading the room on X — pulling top posts and synthesizing themes…

Source: X recent search ranked by engagement (likes + retweets) · Synthesis by Claude · Cached for 1 hour

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