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Pi-Cardia

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A medical device start-up company developing a novel low profile catheter for the treatment of Aortic Stenosis

Rehovot, IsraelFounded 2009Health Tech & Medtech
Valuation $250–500M Last recorded · 2026
Headcount <100 Current team size
Total funding $100–500M Disclosed equity funding
Unlock exact values This page shows ranges. Dealroom has the exact numbers for Pi-Cardia and the history behind them.

About Pi-Cardia

Pi-Cardia is a medical device company specializing in non-implant based treatments for aortic valve repair. The company's core product, the Leaflex Performer, is designed to treat calcified aortic valves by creating scoring lines that separate calcium deposits, thereby increasing leaflet flexibility and improving valve hemodynamics. This unique mechanism aims to enhance the aortic valve area without the need for implants, offering a less invasive alternative to traditional valve replacement surgeries. Pi-Cardia primarily serves the cardiovascular healthcare market, targeting patients with aortic stenosis, a condition characterized by the narrowing of the aortic valve opening due to calcification. The business model revolves around the development, clinical testing, and eventual commercialization of its proprietary technology. Revenue is generated through the sale of the Leaflex Performer device to hospitals and healthcare providers. The company operates in a highly specialized segment of the medical device industry, focusing on innovative solutions that reduce procedure time, hospitalization duration, and overall healthcare costs.

Source: Dealroom company data

At a glance

Status
Operational
Founded
2009
Headquarters
Rehovot, Israel
Employees
90
Open positions
19
Dealroom signal
90.6/100
Industry
Health
Sub-industry
Medical Devices
Sector
Health Tech & Medtech, Surgery, Cardiology and cardiovascular, Catheters, Valves, Soft Tissues, Surgical Equipment, Tech for Hospitals and Clinics, Hard Tech, DT and LS
Technology
Deep Tech
Business model
Manufacturing
Client focus
b2b

Funding history

6 recorded events

Company financing events and reported valuations.

Deal typeDateAmountValuationInvestorsSource
LATE VC✓Equity / VC Sep 2026 $80M $320M Sofinnova Partners · SPRIG Equity · Jacques R. Seguin · Medtronic ↗
DEBTDebt Jan 2021 $21M — Undisclosed ↗
Showing the latest 2 of 6 recorded eventsBook a demo for the full funding history →

Growth signals

Pi-Cardia website traffic

Latest recorded traffic for Pi-Cardia is 3K monthly website visits, up 257.1% over the last three months. Pi-Cardia's team grew 32.4% over the past year.

Latest monthly visits3K 3-month web change+257.1% 1-year team growth+32.4%
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Similar companies

Closest operating peers by Dealroom taxonomy

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Showing 8 of the closest matchesCompare every metric →

Investments and acquisitions

Capital deployed

Recent portfolio relationships for companies that also act as investors or acquirers.

Investors

11 investors on the cap table

From Dealroom's funding and investor records, grouped by the round each investor first entered.

Seed2 investors entered at this stage

  • Anges Quebec
  • Innogest Capital

Series B and later6 investors entered at this stage

  • Atlante Ventures
  • Clal Biotechnology Industries
  • Sofinnova Partners
  • Medtronic
  • SPRIG Equity
  • Jacques R. Seguin

Other known investors3 additional known investors

  • Claudio Rumazza
  • Indaco Venture Partners
  • JVC Investment Partners
Team profiled 11 named & role-tagged
Founders Hidden — book a demo/100 quality score
Key operators 5 quality Hidden — book a demo/100
Potential founders Hidden — book a demo likely future founders
Startup mafia Hidden — book a demo alumni-founded startups
Talent movements Hidden — book a demo in · Hidden — book a demo out past 12 months

Source: Dealroom Talent Intelligence.

Global footprint

Workforce and web traffic by country
Workforce by country
6 countries with
team presence
🇮🇱 Israel49.3%
🇺🇸 United States16%
🇩🇪 Germany2.7%
🇪🇸 Spain1.3%
🇨🇦 Canada1.3%
Top 5 of 6 shown

Market sentiment

Posts on X, past 7 days

An AI-synthesised read of the highest-engagement posts about Pi-Cardia on X, ranked by likes and reposts, corporate channels excluded.

Reading the room on X — pulling top posts and synthesizing themes…

Source: X recent search ranked by engagement (likes + retweets) · Synthesis by Claude · Cached for 1 hour

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