Perfusio(formerly RFPi)

About Perfusio(formerly RFPi)

Perfusio, formerly known as RFPi, operates in the medical imaging sector, providing advanced tools for real-time assessment of blood flow and tissue perfusion. The company was founded in May 2014, originating from technology developed at East Carolina University by a cross-disciplinary team of surgeons, physicists, and engineers. In 2021, the company rebranded from RFPi to Perfusio. A significant milestone was achieved in December 2018 when its device, Certes™ (previously iCertainty), received Class II 510(k) clearance from the U.S. Food and Drug Administration (FDA), permitting its use in open surgical procedures.

The company's core business revolves around its proprietary AI-powered perfusion imaging system. This technology addresses a critical gap in surgical and wound care, where the misdiagnosis of burn severity can be as high as 50%. The platform provides clinicians with a non-invasive, contact-free method to visualize blood flow and tissue viability instantly, without the need for injections, dyes, or radiation. Its system uses patented Multi-Spectral Laser Imaging (MSLI) to map tissue health, helping surgeons make more informed decisions about treatments, such as surgical timing and debridement planning. This capability is designed to reduce procedural complications, limit unnecessary surgeries, and lower overall healthcare costs.

Perfusio serves a diverse client base that includes burn specialists, trauma and emergency teams, pediatric care providers, and military medics. The technology is designed for a range of environments, from hospital operating rooms and burn units to field care in combat zones. The business model appears to focus on co-development and strategic partnerships with research institutions, medical device manufacturers (OEMs), and military organizations to advance and commercialize its platform. The company has received over $20 million in funding from sources like the NIH and the Department of Defense to support its research and development. In 2020, Monte B. Tucker joined as CEO, and the company established manufacturing and engineering partnerships to scale its operations.