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Orna Therapeutics

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Orna Therapeutics - Ahead of the Curve

Cambridge, United StatesFounded 2019Biotech & Life Sciences
Valuation $1–2.5B Last recorded · 2026
Revenue $100–500M Latest reported FY
Headcount 100–500 Current team size
Total funding $100–500M Disclosed equity funding
Unlock exact values This page shows ranges. Dealroom has the exact numbers for Orna Therapeutics and the history behind them.

About Orna Therapeutics

Ornatx is a pioneering biotech startup that is revolutionizing the field of RNA therapeutics. The company's innovative approach involves shifting from linear to circular RNA, a move that opens up a plethora of possibilities in disease treatment. Ornatx's engineered circular RNA (oRNA™) offers significant advantages over traditional linear forms, making it a promising tool in the fight against various diseases.

The company's technology has wide-ranging applications, spanning multiple disease areas such as cancer, regenerative medicine, protein replacement, infectious diseases, and autoimmunity. Its flagship program is an in situ CAR therapy that uses oRNA™ molecules and proprietary lipid nanoparticles (LNPs) to deliver chimeric antigen receptors (CARs) directly to a patient's immune cells within the body. This innovative therapy could represent a significant advancement over traditional cell engineering therapies.

Ornatx operates in the biotech market, serving clients in the healthcare and medical research sectors. The company's business model revolves around the development and commercialization of its groundbreaking oRNA™ therapeutics. It generates revenue through partnerships with healthcare providers and research institutions, as well as through the potential sale of its therapies once they receive regulatory approval.

The company is led by a team of seasoned scientists, molecular engineers, and industry veterans, including Tom, a veteran entrepreneur with over 20 years of experience in turning scientific visions into successful businesses.

Source: Dealroom company data

At a glance

Founded
2019
Headquarters
Cambridge, United States
Sector
Biotech & Life Sciences
Power Law
Unicorn$1–10B valuation tier

Investors

14 investors on the cap table

From Dealroom's funding and investor records, grouped by the round each investor first entered.

Series A11 investors entered at this stage

  • F2 Ventures
  • Taiho Ventures
  • MPM BioImpact
  • Bristol-Myers Squibb
  • Taiho Pharma
  • Kite Pharma
  • Astellas Venture
  • Novartis Institutes
  • PAG
  • Merck & Co.
  • BioImpact Capital

Series B and later3 investors entered at this stage

  • Massachusetts Institute of Technology
  • BioImpact Capital
  • Merck & Co.
Employees mapped 118 incl. 1 AI specialist
Founders Hidden — book a demo/100 quality score
Key operators 7 quality Hidden — book a demo/100
Potential founders Hidden — book a demo likely future founders
Startup mafia Hidden — book a demo alumni-founded startups
Talent movements Hidden — book a demo in · Hidden — book a demo out past 12 months

Source: Dealroom Talent Intelligence.

Global footprint

Workforce and web traffic by country
Workforce by country
4 countries with
team presence
🇺🇸 United States97.8%
🇪🇸 Spain0.7%
🇪🇹 Ethiopia0.7%
🇦🇺 Australia0.7%
4 countries shown
Web traffic by country
10K monthly visits
across markets
🇺🇸 United States54%
🏳️ Korea19%
🏳️ Republic of13%
🇬🇧 United Kingdom8%
🇮🇳 India5%
Top 5 markets shown

Patents

Estimated portfolio value
$5M

17 active patent families included in this estimate.

A patent family groups patent filings for the same invention. Source: Dealroom · PatSnap.

Explore the patent portfolioPatent records, technology areas and peer comparisonsBook a demo

Market sentiment

Posts on X, past 7 days

An AI-synthesised read of the highest-engagement posts about Orna Therapeutics on X, ranked by likes and reposts, corporate channels excluded.

Reading the room on X — pulling top posts and synthesizing themes…

Source: X recent search ranked by engagement (likes + retweets) · Synthesis by Claude · Cached for 1 hour

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