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Opus Genetics

Biotech & Life Sciences · Raleigh, United States · Founded 2021

A gene therapy company for ultra-rare blinding conditions. Acquired by Opus Genetics | Ocuphire Pharma MoreLess

Opus Genetics is a pioneering biotech startup focused on developing gene therapies for rare inherited retinal diseases (IRDs). These are genetic disorders that cause vision loss and blindness. The company is dedicated to creating advanced treatments that target specific genetic mutations responsible for these conditions.

Opus Genetics primarily serves patients suffering from rare eye diseases, a niche but critical segment of the healthcare market. The company operates in the biotechnology and gene therapy sector, which is a rapidly growing field aimed at treating genetic disorders at their root cause by altering or replacing defective genes.

The business model of Opus Genetics revolves around research and development (R&D) of gene therapies. They are backed by the Retinal Degeneration Fund, the venture arm of the Foundation Fighting Blindness. This backing provides them with both financial support and invaluable insights into patient needs. By focusing on wholly owned programs, Opus Genetics maintains control over their research and development processes, ensuring that their therapies are tailored specifically to the needs of patients with rare retinal diseases.

Opus Genetics makes money through a combination of funding from venture capital, grants, and potentially future revenue from the commercialization of their gene therapies. As their treatments progress through clinical trials and receive regulatory approval, they can be marketed and sold to healthcare providers and directly to patients, generating revenue.

In summary, Opus Genetics is at the forefront of developing groundbreaking gene therapies for rare inherited retinal diseases, leveraging strong financial backing and a patient-centric approach to create innovative treatments.

Keywords: gene therapy, inherited retinal diseases, biotechnology, rare eye diseases, genetic disorders, R&D, venture-backed, patient-centric, clinical trials, AAV-based therapies.

Company overview

Opus Genetics company information

The essential company record, classifications and operating signals in one place.

Status
Acquired
Founded
2021
Headquarters
Raleigh, United States
Employees
5
Open positions
None listed
Dealroom signal
56.2
sub industryBioTechnologyindustryHealthsectorBiotechnologysectorGenetics and genomicssectorSpinoutsectorBiotech and PharmasectorDT and LSsectorscience-based

Valuation & funding

Opus Genetics funding history

Company financing events and reported valuations.

Deal typeDateAmountValuationInvestorsSource
ACQUISITIONExit Oct 2024 $0 Opus Genetics | Ocuphire Pharma
GRANTOther financing Jun 2024 $1.7M Foundation Fighting Blindness
SEEDEquity / VC Jun 2023 $4.5M $95M North Carolina Biotechnology Center
SEEDEquity / VC Sep 2021 $19M $76M Bios Partners · Retinal Degeneration Fund · Manning Family Foundation
SPINOUTOther financing Jan 2021 $0 Harvard Medical School · University of Pennsylvania · Massachusetts Eye and Ear
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Financials

Workforce over time

Available workforce history. Financial fields without reported data are omitted.

YearEmployees
2026 5
2025 5
2024 5
2023 11
2022 21
2021 6
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Growth signals

Opus Genetics website traffic

Latest recorded traffic for Opus Genetics is 6.4K monthly website visits, down 5.9% over the last three months. Opus Genetics's team grew 0% over the past year.

Latest monthly visits6.4K 3-month web change-5.9% 1-year team growth0%
Monthly website visits35 observations · Oct 2022–Jan 2026
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Comparisons

Opus Genetics compared with similar companies

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Talent graph

Opus Genetics's talent

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Team profiled 9 named & role-tagged
Founders Hidden — book a demo/100 quality score
Key operators 5 quality Hidden — book a demo/100
Potential founders Hidden — book a demo likely future founders
Startup mafia Hidden — book a demo alumni-founded startups
Talent movements Hidden — book a demo in · Hidden — book a demo out past 12 months

Source: Dealroom Talent Intelligence.

Investors

9 investors on Opus Genetics's cap table

Sourced from Dealroom's funding and investor records.

Seed 5 investors entered at this stage
Retinal Degeneration Fund
Bios Partners
Manning Family Foundation
North Carolina Biotechnology Center
Foundation Fighting Blindness
Other known 4 additional known investors
Harvard Medical School
Massachusetts Eye and Ear
Opus Genetics | Ocuphire Pharma
University of Pennsylvania

Global footprint

Where Opus Genetics has talent and traffic

Workforce by country
1 countries with
team presence
🇺🇸 United States100%
1 country shown

In the news

Latest news about Opus Genetics

Recent press, funding announcements, and product moves mentioning Opus Genetics — open to read from the original sources.

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Market sentiment

What the market is saying about Opus Genetics

An AI-synthesized read of the highest-engagement posts about Opus Genetics on X over the past 7 days. We rank by likes & retweets, ignore corporate channels, and surface the themes that broke out from real people.

Reading the room on X — pulling top posts and synthesizing themes…

Source: X recent search ranked by engagement (likes + retweets) · Synthesis by Claude · Cached for 1 hour

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