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Matchpoint

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Designing a new era of precision covalent medicines informed by breakthroughs in ultradeep chemoproteomics and machine learning

Watertown, United StatesFounded 2021Biotech & Life Sciences
Valuation $250–500M Last recorded · 2022
Headcount <100 Current team size
Total funding $100–500M Disclosed equity funding
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About Matchpoint

Matchpoint Therapeutics is a startup that operates in the biotechnology sector, specifically focusing on the development of precision covalent medicines for immune diseases. Covalent medicines are drugs that form an irreversible bond with their protein target, which allows for more precise targeting of disease-causing proteins. This approach has the potential to greatly expand the number of proteins that can be therapeutically targeted, and offers improved potency over non-covalent approaches.

Matchpoint's business model revolves around the discovery and development of these precision small molecule medicines. They use advanced techniques such as chemoproteomics screening, which allows them to detect binding pockets that would be missed with traditional screening methods. This results in a more durable target engagement, which in turn leads to more effective treatments.

The company also leverages machine learning to extract insights from extensive data sets, including their proprietary chemoproteomics screens, publicly available data, and predictors of protein conformation and protein-protein interaction. This helps them design algorithms that can further refine their drug discovery process.

Matchpoint Therapeutics serves a market that includes patients suffering from various immune diseases. They generate revenue through the development and commercialization of their covalent medicines. The company recently launched with a funding of $100 million, indicating strong investor confidence in their innovative approach to drug discovery and development.

Source: Dealroom company data

At a glance

Status
Operational
Founded
2021
Headquarters
Watertown, United States
Employees
32
Open positions
None listed
Dealroom signal
41.3/100
Industry
Health
Sub-industry
Pharmaceutical, BioTechnology
Sector
Biotech & Life Sciences, Biotechnology, Drug Development, Spinout, Biotech and Pharma, proteomics, DT and LS, science-based
Business model
Manufacturing
Client focus
b2b

Funding history

3 recorded events

Company financing events and reported valuations.

Deal typeDateAmountValuationInvestorsSource
SERIES AOther financing Oct 2022 $70M $280M Alexandria Venture Investments · Digitalis Ventures · Vertex Ventures HC · Access Biotechnology ↗
SEEDOther financing Nov 2021 $30M $120M Atlas Venture · Access Biotechnology ↗
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Growth signals

Matchpoint website traffic

Latest recorded traffic for Matchpoint is 100 monthly website visits, down 94.1% over the last three months. Matchpoint's team grew 14.3% over the past year.

Latest monthly visits100 3-month web change-94.1% 1-year team growth+14.3%
Summary metrics are public; monthly history is available with a demoCompare with peers →

Similar companies

Closest operating peers by Dealroom taxonomy

Company identity and context are open; selected comparison metrics preview what is available on the platform.

CompanyHeadquartersStatusEmployeesTotal fundingValuation
CatenaBioCatena biosciences's mission is to create new therapies for cancer, vaccines, and to retrain the immune system to cure autoimmune disorders Berkeley, United States Operational 18 $4.8M $9.4M
BSIM TherapeuticsSmall Molecule Therapeutics against Transthyretin-Mediated Amyloidoses Coimbra, Portugal Operational
Juvena TherapeuticsA biopharmaceutical platform which is discovering novel protein-based therapeutics Palo Alto, United States Operational
1910 GeneticsA biotechnology company integrating AI, computation, and biological automation to accelerate the design of small molecule and protein therapeutics Boston, United States Operational
Myris TherapeuticsA transformational platform company that develops next-generation nanoarmored protein-polymer conjugates Pittsburgh, United States Operational
Sibylla BiotechFacing the complexity of drug discovery with the power of an innovative approach for meeting unmet medical needs Bresso, Italy Operational
Menten AILeverages synthetic biology, machine learning and quantum computing to create new proteins not found in nature for diverse applications in the pharmaceutical and chemical industries San Francisco, United States Operational
Protein FoundryProtein Foundry produces bacterial and virus vaccines, toxoids, and analogous products Milwaukee, United States Operational
Showing 8 of the closest matchesCompare every metric →

Investments and acquisitions

Capital deployed

Recent portfolio relationships for companies that also act as investors or acquirers.

Investors

7 investors on the cap table

From Dealroom's funding and investor records, grouped by the round each investor first entered.

Seed2 investors entered at this stage

Series A4 investors entered at this stage

  • Sanofi Ventures
  • Alexandria Venture Investments
  • Digitalis Ventures
  • Vertex Ventures HC

Other known investors1 additional known investor

  • University of Florida
Team profiled 4 named & role-tagged
Founders Hidden — book a demo/100 quality score
Key operators Hidden — book a demo quality score
Potential founders Hidden — book a demo likely future founders
Startup mafia Hidden — book a demo alumni-founded startups
Talent movements Hidden — book a demo in · Hidden — book a demo out past 12 months

Source: Dealroom Talent Intelligence.

Global footprint

Workforce and web traffic by country
Workforce by country
1 countries with
team presence
🇺🇸 United States100%
1 country shown

Market sentiment

Posts on X, past 7 days

An AI-synthesised read of the highest-engagement posts about Matchpoint on X, ranked by likes and reposts, corporate channels excluded.

Reading the room on X — pulling top posts and synthesizing themes…

Source: X recent search ranked by engagement (likes + retweets) · Synthesis by Claude · Cached for 1 hour

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