COMPANY PROFILE

I-Mab Biopharma

I-Mab is a dynamic, global biotech company exclusively focused on discovery, development and soon commercialization of novel or highly differentiated biologics in the therapeutic areas of…

Huangpu, ChinaFounded 2016Biotech & Life Sciences

Valuation $186M Market cap · 2026

Revenue $3.9M Latest reported FY

Total funding $500M–1B Disclosed equity funding

About I-Mab Biopharma

I-Mab Biopharma is a clinical-stage biopharmaceutical company established in 2016 by Dr. Jingwu Zang, an immunologist and entrepreneur. Initially founded in Shanghai, China, the company has transitioned to a U.S.-based global biotech with operations in Rockville, Maryland, and San Diego, California. This strategic shift involved the divestiture of its China-based operations in April 2024, a move designed to streamline the organization and focus on ex-China markets. The company's business model centers on the discovery, development, and commercialization of biologics, particularly in immuno-oncology. Revenue generation is primarily driven by licensing agreements, co-development collaborations with global pharmaceutical companies, and royalties from commercialized products. Since its inception, I-Mab has secured significant funding, including a $150 million Series B in 2017, a $220 million Series C in 2018, and a successful IPO on the Nasdaq in 2020 which raised approximately $104 million.

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The company's pipeline is focused on differentiated immunotherapies for cancer. Key assets include Givastomig, a bispecific antibody targeting CLDN18.2 and 4-1BB for gastric and esophageal cancers, which is being developed in collaboration with ABL Bio. Another significant candidate is Uliledlimab, an antibody targeting CD73 to counteract immunosuppression in the tumor microenvironment, being studied for non-small cell lung cancer. Ragistomig, a bispecific antibody targeting PD-L1 and 4-1BB, is under development for solid tumors that are resistant to checkpoint inhibitors. I-Mab's strategy involves forming strategic global partnerships to advance its drug candidates, such as its clinical collaboration and supply agreement with Bristol Myers Squibb to evaluate givastomig in combination with nivolumab.

Financially, I-Mab maintains a solid cash position to fund its operations and clinical trials. As of June 30, 2024, the company reported cash, cash equivalents, and short-term investments of $207.5 million, with a projected cash runway into 2027. The company has been actively managing its expenses, with a reported net loss from continuing operations of $17.8 million for the first six months of 2024, a decrease from $37.9 million for the same period in 2023. The leadership team, which has undergone restructuring to support its U.S.-based model, includes experienced professionals from the pharmaceutical industry. The company is publicly traded on the Nasdaq under the ticker IMAB.

Source: Dealroom company data