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HistoSonics

Health Tech & Medtech · Minneapolis, United States · Founded 2009

Non-invasive tumor destruction using focused ultrasound MoreLess

HistoSonics is pioneering a non-invasive, robotically assisted platform that utilizes focused sound energy to mechanically destroy diseased tissue at a sub-cellular level. The company operates in the medical technology sector, primarily serving healthcare providers and patients. HistoSonics' core technology, known as histotripsy, offers a non-ionizing and non-thermal treatment option, making it a safer alternative to traditional methods. The business model revolves around the development and commercialization of its proprietary platform, Edison™, which provides real-time treatment monitoring and procedural control. Revenue is generated through the sale of the Edison™ platform and associated services, including clinical trials and ongoing support. HistoSonics is currently conducting clinical trials in the United States and Europe under the HOPE4LIVER initiative, aiming to bring this innovative treatment to a broader market.

Keywords: histotripsy, non-invasive, robotically assisted, focused sound energy, sub-cellular, medical technology, Edison™, clinical trials, HOPE4LIVER, real-time monitoring.

Valuation $2.5–5B
Revenue $100–500M
Headcount 100–500
Total funding $500M–1B
Unlock exact values This page shows ranges. Dealroom has the exact numbers for HistoSonics and the history behind them.

Talent graph

HistoSonics's talent

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Employees mapped 429 incl. 1 AI specialist
Founders Hidden — book a demo/100 quality score
Key operators 8 quality Hidden — book a demo/100
Potential founders Hidden — book a demo likely future founders
Startup mafia Hidden — book a demo alumni-founded startups
Talent movements Hidden — book a demo in · Hidden — book a demo out past 12 months

Source: Dealroom Talent Intelligence.

Investors

26 investors on HistoSonics's cap table

Sourced from Dealroom's funding history. Investor profile links are shown where available.

Series A 7 investors entered at this stage
Venture Investors Health Fund
Fletcher Spaght, Inc.
Hatteras Venture Partners
TGap Ventures
Fletcher Spaght Ventures
Early Stage Partners
UM-MINTS
Series B+ 19 investors entered at this stage
Grand Rapids Business Journal
Grand Angels
Capital Community Angel Investors
HistoSonics
Varian Medical Systems
Johnson & Johnson Innovation
Lumira Ventures
State of Wisconsin Investment Board
Yonjin Venture
Signature Bank
Alpha Wave Global
HealthQuest Capital
Amzak Health
Wellington Management
Thiel Bio
K5 Global
Bezos Expeditions
Yosemite
Reed Jobs

Global footprint

Where HistoSonics has talent and traffic

Workforce by country
8 countries with
team presence
🇺🇸 United States95.6%
🇷🇸 Serbia1.9%
🇪🇸 Spain0.6%
🇸🇬 Singapore0.6%
🇦🇪 United Arab Emirates0.3%
Top 5 of 8 shown
Web traffic by country
13K monthly visits
across markets
🇺🇸 United States53.1%
🇨🇦 Canada21.5%
🇬🇧 United Kingdom13.8%
🇮🇳 India4.6%
🇭🇰 Hong Kong3.8%
Top 5 markets shown

Patent intelligence

$19M patent portfolio · 36 active families

Estimated portfolio value
$19M
0.50% of valuation · 2.6× larger than top peer Eight Sleep ($7M)
36 active patent families
Where HistoSonics innovates AcousticsBiomedical engineeringHistotripsyMedical physicsMinimal invasiv

Where HistoSonics concentrates vs peers

Each axis is a top-10 topic across HistoSonics and its closest peers. #1 = 100, #10 = 10, absent = 0.

Compare against

Source: Dealroom Patent Intelligence · Patsnap. Request a demo for the full per-sub-category breakdown, individual records, and quality-score history.

Market sentiment

What the market is saying about HistoSonics

An AI-synthesized read of the highest-engagement posts about HistoSonics on X over the past 7 days. We rank by likes & retweets, ignore corporate channels, and surface the themes that broke out from real people.

Reading the room on X — pulling top posts and synthesizing themes…

Source: X recent search ranked by engagement (likes + retweets) · Synthesis by Claude · Cached for 1 hour

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