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EnPlusOne Biosciences

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On a mission to bring RNA and RNA solutions to the world

Watertown, United StatesFounded 2022Biotech & Life Sciences
Valuation $50–100M Last recorded · 2025
Headcount <100 Current team size
Total funding $10–50M Disclosed equity funding
Unlock exact values This page shows ranges. Dealroom has the exact numbers for EnPlusOne Biosciences and the history behind them.

About EnPlusOne Biosciences

EnPlusOne Biosciences is a cutting-edge startup operating in the biotechnology sector. The company specializes in the development and commercialization of advanced RNA synthesis technologies. Specifically, EnPlusOne Bio has secured a worldwide, exclusive licensing agreement to commercialize a novel, controlled enzymatic RNA oligonucleotide synthesis technology developed at the Wyss Institute for Biologically Inspired Engineering at Harvard University. This technology allows for more precise and efficient production of RNA molecules, which are crucial for various applications in research, diagnostics, and therapeutics.

The primary clients of EnPlusOne Bio include pharmaceutical companies, research institutions, and biotechnology firms. These clients utilize RNA molecules for drug development, genetic research, and diagnostic tests. By providing a more efficient and controlled method of RNA synthesis, EnPlusOne Bio aims to enhance the capabilities of these organizations, enabling them to achieve more accurate results and faster development times.

EnPlusOne Bio operates within the broader life sciences market, which encompasses sectors such as molecular diagnostics, synthetic biology, and environmental sciences. The company’s business model is based on licensing its proprietary RNA synthesis technology to other firms and institutions. Additionally, EnPlusOne Bio may offer custom RNA synthesis services, providing tailored solutions to meet the specific needs of its clients.

Revenue generation for EnPlusOne Bio primarily comes from licensing fees and service contracts. By offering a unique and highly specialized technology, the company positions itself as a valuable partner for organizations looking to advance their RNA-related research and development efforts.

In summary, EnPlusOne Biosciences is a biotech startup focused on revolutionizing RNA synthesis. It serves pharmaceutical companies, research institutions, and biotech firms, operating in the life sciences market. The company makes money through licensing its technology and offering custom synthesis services.

Source: Dealroom company data

At a glance

Status
Operational
Founded
2022
Headquarters
Watertown, United States
Employees
26
Open positions
None listed
Dealroom signal
69.2/100
Industry
Health
Sub-industry
BioTechnology
Sector
Biotech & Life Sciences, Biotechnology, Spinout, Biotech and Pharma, DT and LS, science-based
Business model
Manufacturing
Client focus
b2b

Funding history

3 recorded events

Company financing events and reported valuations.

Deal typeDateAmountValuationInvestorsSource
EARLY VC✓Equity / VC Feb 2025 $10M $60M Breakout Ventures · Northpond Ventures ↗
SEED✓Equity / VC Sep 2022 $12M $48M Coatue Management · Breakout Ventures · Northpond Ventures ↗
Showing the latest 2 of 3 recorded eventsBook a demo for the full funding history →

Growth signals

EnPlusOne Biosciences website traffic

Latest recorded traffic for EnPlusOne Biosciences is 1.7K monthly website visits, up 21.4% over the last three months. EnPlusOne Biosciences's team declined 10.3% over the past year.

Latest monthly visits1.7K 3-month web change+21.4% 1-year team growth-10.3%
Summary metrics are public; monthly history is available with a demoCompare with peers →

Similar companies

Closest operating peers by Dealroom taxonomy

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Showing 8 of the closest matchesCompare every metric →

Investments and acquisitions

Capital deployed

Recent portfolio relationships for companies that also act as investors or acquirers.

Investors

5 investors on the cap table

From Dealroom's funding and investor records, grouped by the round each investor first entered.

Seed3 investors entered at this stage

Other known investors2 additional known investors

  • Harvard University
  • Julia (Thies) Moore
Team profiled 4 named & role-tagged
Founders Hidden — book a demo/100 quality score
Key operators 2 quality Hidden — book a demo/100
Potential founders Hidden — book a demo likely future founders
Startup mafia Hidden — book a demo alumni-founded startups
Talent movements Hidden — book a demo in · Hidden — book a demo out past 12 months

Source: Dealroom Talent Intelligence.

Global footprint

Workforce and web traffic by country
Workforce by country
1 countries with
team presence
🇺🇸 United States100%
1 country shown

Market sentiment

Posts on X, past 7 days

An AI-synthesised read of the highest-engagement posts about EnPlusOne Biosciences on X, ranked by likes and reposts, corporate channels excluded.

Reading the room on X — pulling top posts and synthesizing themes…

Source: X recent search ranked by engagement (likes + retweets) · Synthesis by Claude · Cached for 1 hour

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