C
Cytospire Therapeutics
Harnessing the immune system to create next-generation cancer treatments
About Cytospire Therapeutics
Cytospire Therapeutics is a London biotechnology company founded in 2023 by Dr Natalie Mount (formerly Adaptate Biotherapeutics / GammaDelta Therapeutics and Pfizer) developing pan-gamma delta (γδ) T cell engager immunotherapies for solid tumours. Its multispecific antibody platform bridges γδ T cells to tumour antigens, aiming for potent anti-tumour activity with lower toxicity than conventional CD3 T-cell engagers; lead program CYT X300 targets EGFR-positive cancers such as colorectal, head-and-neck and NSCLC. In May 2026 Cytospire closed an oversubscribed £61 million ($83 million) Series A led by 4BIO Capital, with Servier Ventures, the British Business Bank, Abingworth, LifeArc Ventures, Sound Bioventures, Criteria Bio and others, to advance CYT X300 through IND-enabling studies into first-in-human trials. Sources: GlobeNewswire / 4BIO Capital 5 May 2026; company announcement.
Source: Dealroom company dataAt a glance
- Status
- Operational
- Founded
- 2023
- Headquarters
- London, United Kingdom
- Employees
- 21
- Open positions
- None listed
- Dealroom signal
- 57.7/100
- Industry
- Health
- Sub-industry
- BioTechnology
- Sector
- Biotech & Life Sciences, Biotechnology, Biotech and Pharma, DT and LS
- Business model
- Manufacturing
- Client focus
- b2b
Knowledge graph
More headlines
Funding history
Company financing events and reported valuations.
| Deal type | Date | Amount | Valuation | Investors | Source |
|---|---|---|---|---|---|
| SERIES AOther financing | May 2026 | $81M | $322M | Abingworth · British Business Bank · Sound Bioventures · Modi Venture Partners | ↗ |
Growth signals
Latest recorded traffic for Cytospire Therapeutics is 1.3K monthly website visits, up 56.6% over the last three months. Cytospire Therapeutics's team grew 75% over the past year.
Similar companies
Company identity and context are open; selected comparison metrics preview what is available on the platform.
| Company | Headquarters | Status | Employees | Total funding | Valuation |
|---|---|---|---|---|---|
ScancellClinical-stage immunotherapies for difficult-to-treat cancers |
Oxford, United Kingdom | Operational | 58 | $5.9M | $145M |
KymabHuman monoclonal antibody discovery and development platform |
Babraham, United Kingdom | Acquired | |||
Amphista TherapeuticsNext-generation therapeutics for targeted protein degradation |
Great Abington, United Kingdom | Operational | |||
TC BiopharmAllogeneic gamma-delta T-cell therapies for cancer |
Holytown, United Kingdom | Operational | |||
| China | Operational | ||||
Mestag TherapeuticsDeveloping antibody therapeutics targeting fibroblast-immune interactions |
Little Chesterford, United Kingdom | Operational | |||
Leucid BioNext-generation CAR-T cell therapies for refractory cancers |
London, United Kingdom | Operational | |||
IstessoDeveloping adaptive tissue-repair drugs for chronic diseases |
London, United Kingdom | Operational |
Investments and acquisitions
Recent portfolio relationships for companies that also act as investors or acquirers.
Investors
From Dealroom's funding and investor records, grouped by the round each investor first entered.
Series A10 investors entered at this stage
4BIO Capital
Abingworth
British Business Bank
Sound Bioventures
Modi Venture Partners
LifeArc Ventures
Criteria Bio Ventures
Servier
Medical Incubator Japan
Pathway Bioventures
Source: Dealroom Talent Intelligence.
Global footprint
team presence
Market sentiment
An AI-synthesised read of the highest-engagement posts about Cytospire Therapeutics on X, ranked by likes and reposts, corporate channels excluded.
Reading the room on X — pulling top posts and synthesizing themes…
Source: X recent search ranked by engagement (likes + retweets) · Synthesis by Claude · Cached for 1 hour
See Cytospire Therapeutics’s full profile on Dealroom
Request a free trial to see the complete deal history, financials, people graph and growth signals.
Takes under a minute. Already use Dealroom? Log in.






