CoreValve

CoreValve is a medical device company that was acquired by Medtronic in 2009 for $700 million. The company specializes in transcatheter aortic valve replacement (TAVR) systems, which are minimally invasive procedures to replace a diseased aortic valve.

The CoreValve system is designed for patients with severe aortic stenosis who are at high risk for open-heart surgery. The system is delivered through a catheter, which is inserted into an artery in the leg or chest and guided to the heart. The new valve is then deployed, pushing the old valve out of the way and taking over the function of regulating blood flow.

The company's flagship product is the CoreValve Evolut PRO+ system, which is the latest generation of the CoreValve platform. The Evolut PRO+ system features a self-expanding nitinol frame and a porcine pericardial tissue valve. The system is designed to provide excellent hemodynamics, low rates of paravalvular leak, and a low risk of pacemaker implantation.

CoreValve's products are sold to hospitals and other healthcare facilities around the world. The company's primary customers are interventional cardiologists and cardiac surgeons.

Keywords: medical devices, transcatheter aortic valve replacement, TAVR, aortic stenosis, minimally invasive surgery, cardiac surgery, interventional cardiology, nitinol frame, porcine pericardial tissue valve, Medtronic