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Constructive Bio

Biotech & Life Sciences · Cambridge, United Kingdom · Founded 2021

Realising the potential of genome rewriting to drive the next generation of bioprocesses and biopharmaceuticals MoreLess

Constructive Bio is a UK-based biotechnology company focused on re-engineering biology by creating synthetic genomes from scratch.

The company's core technology involves rewriting and reprogramming the genetic code of bacterial strains. By hijacking the cell's protein translation machinery, they can synthesize novel biopolymers and programmable biomolecules with high fidelity and scalability.

This capability allows for the creation of new classes of enzymes, pharmaceuticals, and biomaterials, targeting the drug discovery and biomanufacturing sectors.

The company operates on a B2B model, providing its technology for various commercial applications. Constructive Bio has secured significant venture funding, including a $15 million seed round and a $58 million Series A financing, to advance its genome synthesis platform.

Keywords: synthetic biology, genome synthesis, genetic code reprogramming, biomolecules, biopolymers, drug discovery, biomanufacturing, protein translation, enzymes, pharmaceuticals

Company overview

Constructive Bio company information

The essential company record, classifications and operating signals in one place.

Status
Operational
Founded
2021
Headquarters
Cambridge, United Kingdom
Employees
69
Open positions
6
Dealroom signal
92.8
client focusb2btechnologyHardwaretechnologyDeep Techsub industryBioTechnologybusiness modelManufacturingindustryHealthsectorBiotechnologysectorSynthetic BiologysectorSpinoutsectorIndustrial TechnologysectorAdvanced MaterialssectorBioeconomysectorBIA Techbio UKsectorTechbio

Valuation & funding

Constructive Bio funding history

Company financing events and reported valuations.

Deal typeDateAmountValuationInvestorsSource
EARLY VCOther financing Mar 2026 $20M $284M Undisclosed
EARLY VCOther financing Apr 2025 $0 LongeVC
GRANTOther financing Feb 2025 $749K UK Research and Innovation
SERIES AOther financing Sep 2024 $58M $232M Jonathan Milner · Ahren Innovation Capital · OMX Ventures · +ND Capital
SEEDOther financing Aug 2022 $17M $66M General Inception · Ahren Innovation Capital · Amadeus Capital Partners · OMX Ventures
SPINOUTOther financing Nov 2021 MRC Laboratory of Molecular Biology · University of Cambridge
Showing 6 recorded eventsUnlock the complete deal history →

Growth signals

Constructive Bio website traffic

Latest recorded traffic for Constructive Bio is 7K monthly website visits, up 52.2% over the last three months. Constructive Bio's team grew 16.9% over the past year.

Latest monthly visits7K 3-month web change+52.2% 1-year team growth+16.9%
Monthly website visits41 observations · Jan 2023–Jul 2026
Hover or focus a point to see its exact monthly valueCompare with peers →

Comparisons

Constructive Bio compared with similar companies

Dealroom’s weighted taxonomy model identifies the closest operating peers. Company identity and context stay open; selected comparison metrics preview what is available in the platform.

CompanyHeadquartersStatusEmployeesTotal fundingValuation
SynthaceEngineering biology for health, food, energy and manufacturing. London, United Kingdom Operational 35 $82M $172M
BactobioLondon-based biotechnology company using breakthrough technologies in synthetic biology London, United Kingdom Operational
Touchlight GeneticsDevelops a DNA production platform designed for the development of DNA vaccines for oncology and infectious diseases London, United Kingdom Operational
LabGeniusCombining human and machine intelligence to accelerate the discovery of advanced medicines London, United Kingdom Operational
IntellegensHelping clients accelerate innovation by using our unique deep learning solutions to extract valuable information from existing processes and data Cambridge, United Kingdom Operational
Epoch BiodesignDesigning and scaling the first enzymes capable of transforming plastics into low-carbon, circular chemicals London, United Kingdom Operational
EvonetixUr desktop DNA synthesis platform will provide the ability to synthesise DNA at unprecedented accuracy, scale and speed, accelerating scientists'​ ability to use synthetic biology on a scale not currently possible Cambridge, United Kingdom Operational
CardiaTecApplying artificial intelligence on large-scale human multiomic data to develop the next generation of cardiovascular disease targets Cambridge, United Kingdom Operational
Showing 8 of the closest matchesCompare every metric →

Talent graph

Constructive Bio's talent

Book a demo to see the people
Team profiled 6 named & role-tagged
Founders Hidden — book a demo/100 quality score
Key operators 2 quality Hidden — book a demo/100
Potential founders Hidden — book a demo likely future founders
Startup mafia Hidden — book a demo alumni-founded startups
Talent movements Hidden — book a demo in · Hidden — book a demo out past 12 months

Source: Dealroom Talent Intelligence.

Investors

12 investors on Constructive Bio's cap table

Sourced from Dealroom's funding and investor records. Investor profile links are shown where available.

Seed 5 investors entered at this stage
Ahren Innovation Capital
General Inception
Amadeus Capital Partners
OMX Ventures
UK Research and Innovation
Series A 5 investors entered at this stage
Paladin Capital Group
Jonathan Milner
+ND Capital
Fine Structure Ventures
LongeVC
Other known 2 additional known investors
MRC Laboratory of Molecular Biology
University of Cambridge

Global footprint

Where Constructive Bio has talent and traffic

Workforce by country
4 countries with
team presence
🇬🇧 United Kingdom90%
🇨🇭 Switzerland4%
🇺🇸 United States4%
🇨🇿 Czech Republic2%
4 countries shown

In the news

Latest news about Constructive Bio

Recent press, funding announcements, and product moves mentioning Constructive Bio — open to read from the original sources.

See all news

Market sentiment

What the market is saying about Constructive Bio

An AI-synthesized read of the highest-engagement posts about Constructive Bio on X over the past 7 days. We rank by likes & retweets, ignore corporate channels, and surface the themes that broke out from real people.

Reading the room on X — pulling top posts and synthesizing themes…

Source: X recent search ranked by engagement (likes + retweets) · Synthesis by Claude · Cached for 1 hour

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