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Confo Therapeutics

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Drug discovery platform targeting previously inaccessible GPCRs

Ghent, BelgiumFounded 2015Biotech & Life Sciences
Valuation $250–500M Last recorded · 2024
Revenue $50–100M Latest reported FY
Headcount <100 Current team size
Total funding $100–500M Disclosed equity funding
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About Confo Therapeutics

Confo Therapeutics is a clinical-stage biopharmaceutical company that specializes in the discovery of medicines targeting G-protein coupled receptors (GPCRs). The company was spun out in 2015 from Vrije Universiteit Brussel (VUB) and the Flanders Institute for Biotechnology (VIB). Its foundation is based on the proprietary ConfoBody™ technology developed in the lab of Professor Jan Steyaert, a scientific founder of the company. This technology utilizes single-domain antibodies, or "ConfoBodies™," derived from camelids to stabilize GPCRs in specific, functionally relevant conformations that are otherwise inherently unstable. This stabilization allows for the identification of novel drug candidates against GPCR targets that were previously considered undruggable.

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The company's CEO is Dr. Cedric Ververken, who joined in 2016 from Ablynx, bringing experience in both R&D and business development. Confo Therapeutics focuses its internal pipeline on developing treatments for metabolic and endocrine diseases, including rare diseases and obesity. One of its lead candidates, CFTX-1554, is a non-opioid treatment for neuropathic pain that targets the angiotensin II type 2 receptor (AT2R). The business model involves advancing its own pipeline of drug candidates while also engaging in strategic collaborations with major pharmaceutical companies like Roche and Lundbeck. Revenue is generated through these partnerships and the potential future commercialization of its in-house developed therapeutics.

Confo Therapeutics has secured significant funding from an international consortium of life science investors. After initial seed funding, the company raised €30 million in a Series A round in 2019 and more recently, €60 million in a Series B financing in July 2024. This funding is aimed at advancing its lead programs through clinical trials and expanding its discovery platform to include small molecules and agonistic antibodies.

Source: Dealroom company data

At a glance

Founded
2015
Headquarters
Ghent, Belgium
Sector
Biotech & Life Sciences
Power Law
Colt$25–100M revenue

Investors

25 investors on the cap table

From Dealroom's funding and investor records, grouped by the round each investor first entered.

Seed4 investors entered at this stage

  • Capricorn Partners
  • Qbic Fund
  • VLAIO- Team Bedrijfstrajecten Crossroads France-Wallonie-Vlaanderen
  • Flemish Department for Innovation and Entrepreneurship

Series A13 investors entered at this stage

  • The Institute for the Promotion of Innovation by Science and Technology in Flanders
  • Wellington Partners
  • BioGeneration Ventures
  • PMV
  • V-Bio Ventures
  • Perceptive Advisors
  • Ackermans & van Haaren
  • BioGenerator
  • FundPlus
  • University of Michigan
  • Quest for Growth
  • Flanders Institute for Biotechnology
  • Driehaus Capital Management

Series B and later8 investors entered at this stage

  • Ackermans & van Haaren
  • BioGenerator
  • Flanders Institute for Biotechnology
  • Quest for Growth
  • Driehaus Capital Management
  • Vrije Universiteit Brussel
  • FundPlus
  • University of Michigan
Team profiled 17 named & role-tagged
Founders Hidden — book a demo/100 quality score
Key operators 5 quality Hidden — book a demo/100
Potential founders Hidden — book a demo likely future founders
Startup mafia Hidden — book a demo alumni-founded startups
Talent movements Hidden — book a demo in · Hidden — book a demo out past 12 months

Source: Dealroom Talent Intelligence.

Global footprint

Workforce and web traffic by country
Workforce by country
6 countries with
team presence
🇧🇪 Belgium88.7%
🇬🇧 United Kingdom4.8%
🇺🇸 United States1.6%
🇩🇪 Germany1.6%
🇫🇷 France1.6%
Top 5 of 6 shown
Web traffic by country
4.3K monthly visits
across markets
🇧🇪 Belgium55.8%
🇺🇸 United States25.6%
🇮🇳 India18.6%
Top 3 markets shown

Market sentiment

Posts on X, past 7 days

An AI-synthesised read of the highest-engagement posts about Confo Therapeutics on X, ranked by likes and reposts, corporate channels excluded.

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Source: X recent search ranked by engagement (likes + retweets) · Synthesis by Claude · Cached for 1 hour

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