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Circle Pharma

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Early stage biotechnology company applying proprietary

South San Francisco, United StatesFounded 2012Biotech & Life Sciences
Valuation $250–500M Last recorded · 2024
Headcount <100 Current team size
Total funding $100–500M Disclosed equity funding
Unlock exact values This page shows ranges. Dealroom has the exact numbers for Circle Pharma and the history behind them.

About Circle Pharma

Circle Pharma is a biotechnology company focused on developing innovative macrocyclic peptide therapeutics to address challenging intracellular targets, particularly in oncology. The company operates in the pharmaceutical and biotechnology market, serving clients such as pharmaceutical companies and research institutions. Circle Pharma's business model revolves around its proprietary discovery engine, which combines computational structure-based design with automated synthetic chemistry to create cell-permeable macrocycles. These macrocycles are designed to target protein-protein interactions that are critical in cancer but have been difficult to address with traditional small molecule drugs. The company generates revenue through collaborations, partnerships, and licensing agreements with major pharmaceutical companies. Circle Pharma's approach leverages advanced computational techniques to screen large virtual libraries of macrocycles, ensuring high target affinity and cell permeability. This innovative method allows the company to develop therapeutics with significant clinical and commercial potential. Keywords: macrocyclic peptides, oncology, intracellular targets, computational design, synthetic chemistry, protein-protein interactions, biotechnology, pharmaceutical, cell permeability, drug discovery.

Source: Dealroom company data

At a glance

Status
Operational
Founded
2012
Headquarters
South San Francisco, United States
Employees
68
Open positions
None listed
Dealroom signal
65.5/100
Industry
Health
Sub-industry
BioTechnology
Sector
Biotech & Life Sciences, Biotechnology, Oncology, Spinout, Biotech and Pharma, proteomics, DT and LS, science-based
Client focus
b2c

Latest news

Press, funding announcements and product moves mentioning Circle Pharma.

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Funding history

7 recorded events

Company financing events and reported valuations.

Deal typeDateAmountValuationInvestorsSource
SERIES DOther financing Sep 2024 $90M $360M Nextech Invest · Euclidean Capital · The Column Group
SERIES COther financing Jun 2021 $66M $264M Pavillion Capital · Euclidean Capital · Eli Lilly · Pandect Bioventures
Showing the latest 2 of 7 recorded eventsBook a demo for the full funding history →

Growth signals

Circle Pharma website traffic

Latest recorded traffic for Circle Pharma is 3.7K monthly website visits, up 76.2% over the last three months. Circle Pharma's team declined 6.8% over the past year.

Latest monthly visits3.7K 3-month web change+76.2% 1-year team growth-6.8%
Summary metrics are public; monthly history is available with a demoCompare with peers →

Similar companies

Closest operating peers by Dealroom taxonomy

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Showing 8 of the closest matchesCompare every metric →

Investors

14 investors on the cap table

From Dealroom's funding and investor records, grouped by the round each investor first entered.

Seed2 investors entered at this stage

  • Mission Bay Capital
  • Pfizer

Series A6 investors entered at this stage

  • ShangPharma
  • WI Harper Group
  • Element Partners
  • Lifeforce Capital
  • The Column Group
  • Nextech Invest

Series B and later5 investors entered at this stage

  • Pavillion Capital
  • Euclidean Capital
  • Eli Lilly
  • Pandect Bioventures
  • Hartford HealthCare Endowment

Other known investors1 additional known investor

  • University of California, San Francisco
Team profiled 8 named & role-tagged
Founders Hidden — book a demo/100 quality score
Key operators 3 quality Hidden — book a demo/100
Potential founders Hidden — book a demo likely future founders
Startup mafia Hidden — book a demo alumni-founded startups
Talent movements Hidden — book a demo in · Hidden — book a demo out past 12 months

Source: Dealroom Talent Intelligence.

Global footprint

Workforce and web traffic by country
Workforce by country
2 countries with
team presence
🇺🇸 United States98.3%
🇨🇭 Switzerland1.8%
2 countries shown

Market sentiment

Posts on X, past 7 days

An AI-synthesised read of the highest-engagement posts about Circle Pharma on X, ranked by likes and reposts, corporate channels excluded.

Reading the room on X — pulling top posts and synthesizing themes…

Source: X recent search ranked by engagement (likes + retweets) · Synthesis by Claude · Cached for 1 hour

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