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Callio Therapeutics

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Biotechnology firm advancing multi-payload ADCs for targeted cancer therapy with innovative HER2 solutions

Seattle, United StatesFounded 2025Biotech & Life Sciences
Valuation $500M–1B Last recorded · 2025
Headcount <100 Current team size
Total funding $100–500M Disclosed equity funding
Unlock exact values This page shows ranges. Dealroom has the exact numbers for Callio Therapeutics and the history behind them.

About Callio Therapeutics

Callio Therapeutics is a biotechnology company headquartered in Seattle and Singapore, dedicated to advancing cancer therapy through the development of next-generation, multi-payload antibody drug conjugates (ADCs). The company focuses on creating ADCs with differentiated payload and linker technologies, enabling the targeted delivery of drug combinations directly to tumor cells. This approach aims to maximize therapeutic benefits for cancer patients. Callio's lead program involves a dual payload HER2 targeted ADC, with plans to achieve clinical proof of concept using funds from a $187 million Series A financing round. The company serves the oncology market, targeting healthcare providers and institutions involved in cancer treatment. Callio's business model revolves around developing and commercializing its ADC platform, generating revenue through partnerships, licensing agreements, and potential acquisitions. The company is led by Adam Simpson, an experienced executive with a background in life sciences and company creation. Keywords: biotechnology, antibody drug conjugates, cancer therapy, HER2, oncology, targeted delivery, tumor cells, clinical proof, financing, Seattle

Source: Dealroom company data

At a glance

Status
Operational
Founded
2025
Headquarters
Seattle, United States
Employees
19
Open positions
None listed
Dealroom signal
93.7/100
Industry
Health
Sub-industry
Pharmaceutical, BioTechnology
Sector
Biotech & Life Sciences, Biotechnology, Oncology, Drug Development, Rumoured $1B, Biotech and Pharma, DT and LS, science-based
Business model
Manufacturing
Client focus
b2b

Funding history

1 recorded event

Company financing events and reported valuations.

Deal typeDateAmountValuationInvestorsSource
SERIES AOther financing Mar 2025 $187M $748M Norwest Venture Partners · Omega Funds · Seeds Capital · Platanus Ventures ↗
Showing the latest 1 of 1 recorded eventsBook a demo for the full funding history →

Growth signals

Callio Therapeutics website traffic

Latest recorded traffic for Callio Therapeutics is 3K monthly website visits, up 11.1% over the last three months. Callio Therapeutics's team grew 18.8% over the past year.

Latest monthly visits3K 3-month web change+11.1% 1-year team growth+18.8%
Summary metrics are public; monthly history is available with a demoCompare with peers →

Similar companies

Closest operating peers by Dealroom taxonomy

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Showing 8 of the closest matchesCompare every metric →

Investments and acquisitions

Capital deployed

Recent portfolio relationships for companies that also act as investors or acquirers.

Investors

10 investors on the cap table

From Dealroom's funding and investor records, grouped by the round each investor first entered.

Series A10 investors entered at this stage

  • Frazier Life Sciences
  • Norwest Venture Partners
  • Omega Funds
  • Seeds Capital
  • Platanus Ventures
  • ClavystBio
  • EDBI
  • Novo Holdings
  • Pureos Bioventures
  • Jeito Capital
Team profiled 3 named & role-tagged
Founders Hidden — book a demo/100 quality score
Key operators 3 quality Hidden — book a demo/100
Potential founders Hidden — book a demo likely future founders
Startup mafia Hidden — book a demo alumni-founded startups
Talent movements Hidden — book a demo in · Hidden — book a demo out past 12 months

Source: Dealroom Talent Intelligence.

Global footprint

Workforce and web traffic by country
Workforce by country
2 countries with
team presence
🇺🇸 United States80%
🇸🇬 Singapore20%
2 countries shown

Market sentiment

Posts on X, past 7 days

An AI-synthesised read of the highest-engagement posts about Callio Therapeutics on X, ranked by likes and reposts, corporate channels excluded.

Reading the room on X — pulling top posts and synthesizing themes…

Source: X recent search ranked by engagement (likes + retweets) · Synthesis by Claude · Cached for 1 hour

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