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BillionToOne

Biotech & Life Sciences · Menlo Park, United States · Founded 2016 · IPO 2025

The only genetic testing platform that accurately and efficiently detects and measures disease at the molecular level MoreLess

BillionToOne is a biotechnology startup that operates in the healthcare sector, specifically in the field of molecular diagnostics. The company's proprietary technology, known as QCT, has the ability to detect and quantify disease at a single base-pair resolution. This means it can identify the tiniest variations in our DNA, which consists of three billion letters or nucleotides.

The company's primary focus is on prenatal screening and oncology testing. Their products, Northstar Select™ and Northstar Response™, are commercially available. Northstar Select™ is used to determine the most suitable first line therapy for patients, while Northstar Response™ monitors the effectiveness of the therapy.

BillionToOne's business model revolves around providing these diagnostic services to healthcare providers. They generate revenue by selling their testing services to these providers, who then use the results to guide their treatment plans.

The company's mission is to make molecular testing more accurate, efficient, and accessible to all. They are driven by a culture of growth, equality, and teamwork, with a strong focus on making a positive impact in healthcare.

The company was founded by Oguzhan Atay, Ph.D., and David Tsao, Ph.D., and is comprised of a team of engineers, scientists, and industry experts who are passionate about improving healthcare through their innovative technology.

Keywords: Biotechnology, Healthcare, Molecular Diagnostics, Prenatal Screening, Oncology Testing, QCT Technology, Northstar Select™, Northstar Response™, DNA Variations, Commercial Diagnostic Services.

Valuation $5–10B
Revenue $100–500M
EBITDA $86M
Headcount 500–1k
Total funding $100–500M

Talent graph

BillionToOne's talent

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Employees mapped 834 incl. 7 AI specialists
Founders Hidden — book a demo/100 quality score
Key operators 8 quality Hidden — book a demo/100
Potential founders Hidden — book a demo likely future founders
Startup mafia Hidden — book a demo alumni-founded startups
Talent movements Hidden — book a demo in · Hidden — book a demo out past 12 months

Source: Dealroom Talent Intelligence.

Investors

21 investors on BillionToOne's cap table

Sourced from Dealroom's funding history. Investor profile links are shown where available.

Seed 6 investors entered at this stage
Y Combinator
Fifty Years
Sanabil Accelerator by 500 Global
Pacific 8 Ventures
Wei Guo
NewDo Venture
Series A 9 investors entered at this stage
Hummingbird Ventures
Neotribe
500 Global
Civilization Ventures
e2vc
HOF Capital
Libertus Capital
Four Rivers Group
Norwest Venture Partners
Series B+ 6 investors entered at this stage
Adams Street Partners
Baillie Gifford
Time BioVentures
Bridge Bank
Premji Invest
Neuberger Berman

Global footprint

Where BillionToOne has talent and traffic

Workforce by country
5 countries with
team presence
🇺🇸 United States97.6%
🇵🇭 Philippines1.5%
🇦🇺 Australia0.3%
🇨🇦 Canada0.3%
🇬🇧 United Kingdom0.2%
5 countries shown
Web traffic by country
26K monthly visits
across markets
🇺🇸 United States78.1%
🇳🇬 Nigeria6.9%
🇬🇧 United Kingdom6.2%
🇯🇵 Japan3.1%
🇹🇷 Turkey2.3%
Top 5 markets shown

Patent intelligence

$26M patent portfolio · 17 active families

Estimated portfolio value
$26M
0.43% of market cap · 4.1× smaller than top peer NanoString Technologies ($106M)
17 active patent families
Where BillionToOne innovates AssayBioinformaticsBiological organismBiological targetCirculating tumor DNA

Where BillionToOne concentrates vs peers

Each axis is a top-10 topic across BillionToOne and its closest peers. #1 = 100, #10 = 10, absent = 0.

Compare against

Source: Dealroom Patent Intelligence · Patsnap. Request a demo for the full per-sub-category breakdown, individual records, and quality-score history.

Market sentiment

What the market is saying about BillionToOne

An AI-synthesized read of the highest-engagement posts about BillionToOne on X over the past 7 days. We rank by likes & retweets, ignore corporate channels, and surface the themes that broke out from real people.

Reading the room on X — pulling top posts and synthesizing themes…

Source: X recent search ranked by engagement (likes + retweets) · Synthesis by Claude · Cached for 1 hour

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